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Doctor insights on: Elevated Sed Rate And Crp And High Rdw

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Sedimentation Rate (Definition)

Is the rate at which red blood cells sediment in a period of 1 hour. It is non-specific measure of inflammation. It is performed by placing anticoagulated blood sample in an upright tube (westergren tube) then measuring the rate at which red blood cells fall (in mm per hour). It is useful in diagnosis of some diseases, such as autoimmune diseases, for assessment of severity of ...Read more


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Crp was elevated now normal and sed rate is a little high. What is the difference?

Crp was elevated now normal and sed rate is a little high. What is the difference?

Inflammation: Both ESR and CRP reflect an inflammatory state. They need to be interpreted in the context of the clinical picture. At any rate, without knowing too much about you, I can say that it is a very good sign that your ESR normalized. A slight elevation of the sedimentation rate is nonspecific and may be meaningless. ...Read more

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Is it normal for CRP and sed rate to be slightly elevated when having a cold?

Is it normal for CRP and sed rate to be slightly elevated when having a cold?

Yes if: Yes if slightly elevated as they are just markers for inflammation. If they are markedly elevated they need an explanation but aren't indicative of any specific disease. ...Read more

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Is it possible to have a normal RA Quantitative result in patient with RA? Sed Rate an CRP still elevated

Is it possible to have a normal RA Quantitative result in patient with RA? Sed Rate an CRP still elevated

Rheumatoid factor: Only 80% of patients with rheumatoid arthritis have a positive rheumatoid factor. Other tests we use include anti-CCP and 14-3-3 eta. I would recommend seeing a rheumatologist. It may be possible to still have rheumatoid arthritis if the test is negative. ...Read more

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Crp was high now normal. Sed rate elevated. Ana+w/speck pattern. Thyroid ok. Metabilic and CBC and urine ok. Little low vitamin d... Any idea?

Crp was high now normal. Sed rate elevated. Ana+w/speck pattern. Thyroid ok. Metabilic and CBC and urine ok. Little low vitamin d... Any idea?

Labs mean little: CRP and sed rate vary greatly for no obvious reason frmo day to day. A majority of americans run a low vitamin d due to our diets & habits. My one concern is if the ANA is at a high-titer, which warns of lupus or a variety of other possibilities, but labs mean nothing apart from the history and physical exam. ...Read more

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Have had mri/ CT scan nothing suspicious. High CRP elevated sed rate. Ana + w/speckled pattern. Could this be cancer? Do have middle back pain.

Have had mri/ CT scan nothing suspicious. High CRP elevated sed rate. Ana + w/speckled pattern. Could this be cancer? Do have middle back pain.

Need further eval: You will need more evaluation. A complete autoimmune panel should be done at least. I don't know your symptoms, but from your limited information, you do have some inflammation process going on in your body and there is a possibility that this may be an autoimmune process. Discuss further with your doctor. ...Read more

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What could cause a CRP of 250 and sed rate of 50? Patient sev chest abd pain. Fever of only 100. Elevated d dimer.

What could cause a CRP of 250 and sed rate of 50? Patient sev chest abd pain. Fever of only 100. Elevated d dimer.

Amy illness: The inflammatory rakers you mentioned are high and indicate illness. Follow up with your md. ...Read more

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Symptoms fatigue / headaches/ malaise. Work up 2008 negative except elevated CRP now elevated CRP 2.73, sed rate 22, ANA positive speck 1:40, ch50>60?

Symptoms fatigue / headaches/ malaise. Work up 2008 negative except elevated CRP now elevated CRP 2.73, sed rate 22, ANA positive speck 1:40, ch50>60?

That's good: I would urge you to draw no conclusion from any sed rate reading that's not extremely high unless there's specific symptoms and signs. Millions of healthy young adults have positive ANA at a titer of 1:40 speckled. I'd urge you to get into a fitness-focused lifestyle, hang out with quality friends and do meaningful things. Best wishes. ...Read more

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Chronic minor petechiae only symptom. CBC, INR/PT, comp. Metabolic, d-dimer, CRP &SED rate normal. APTT elevated 2 seconds. Doc thinks ok. 2nd opinion?

I agree: I would not be concerned. Factor problems measured by PTT do not present this way. If bleeding time and tourniquet test are also near normal, give thanks for good health and forget it. ...Read more

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Elevated total WBC count (11, 000) with elevated total neutrophils, lymphocytes and eosinophils. But CRP & SED rate are NORMAL. What causes this?

Elevated total WBC count (11, 000) with elevated total neutrophils, lymphocytes and eosinophils. But CRP & SED rate are NORMAL. What causes this?

Any symptoms?: Why was the test done? Do you have any symptoms? All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your WBC is at the high end of normal, but it may be your normal.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more

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Ana+w/speck pat. 1:640. Sed rate elevated CRP ok. Cbc and metabolic and urine ok. Up back pain. Fatigue. Right flank pain. Lupus panel negatiive.?

Ana+w/speck pat. 1:640. Sed rate elevated CRP ok. Cbc and metabolic and urine ok. Up back pain. Fatigue. Right flank pain. Lupus panel negatiive.?

Not related to SLE: I'm certain that this ANA is related to your symptoms. You have an elevated sedimentation rate, but there's two things you need to realize. At age 73 you can have a positive ama due to autoimmunity of aging. As we get older our normal level for the sedimentation rate also increases. A simple formula is half your age and for a woman +10. Thus for you your normal sedimentation rate could be 45. Your physician needs to evaluate these issues also. ...Read more

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What is implication homogeneous ANA 1:320, compliment 4 high 44, sed rate and c-reactive protein often elevated and vitamin d low?

What is implication homogeneous ANA 1:320, compliment 4 high 44, sed rate and c-reactive protein often elevated and vitamin d low?

Several causes: The vitamin d is probably a seperate problem and should be treated by a supplement. The other lab you reported can be a sign of an autoimmune disease as well as many other diseases. You should discuss the cause with your doctor. ...Read more

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What is a the implication is chronically elevated Complement 3 and 4 and elevated IGE? Plaquenil has lowered SED rate and C reactive protein.

What is a the implication is chronically elevated Complement 3 and 4 and elevated IGE? Plaquenil has lowered SED rate and C reactive protein.

Infection?: If you are being treated for lupus, a normal C3 is a good thing. However when it is elevated, infection may be the cause. If the IgE is only mildly elevated, it may be from something else such as allergies. But it is highly elevated, one will need to rule out other medical conditions. We really need more details re. Your symptoms. ...Read more

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Can untreated hypothyroidism cause excruciating joint pain, especially in the ankles. Can it cause sed rate and CRP to be high.

Can untreated hypothyroidism cause excruciating joint pain, especially in the ankles. Can it cause sed rate and CRP to be high.

No: It will not elevate the sed rate and crp. The joint pain of severe hypothyroidism is low grade and not excruciating. There is another cause and it isn't thyroid. See a rheumatologist. The one exception is an increased risk of pseudogout which can cause major pain but is unlikely to involve the ankles. ...Read more

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Why is my SED rate normal but my CRP is high?

Why is my SED rate normal but my CRP is high?

There's no knowing: CRP is a single protein; often we do not figure out why it is elevated, and this is never more than a single piece of information in a complex clinical context. Even as an alleged coronary risk factor, it's not something to act on by itself. The sed rate is difficult to do right, and is only ordered on the off-chance it may be useful in spotting uncommon generalized inflammatory illness. Relax. ...Read more

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Dx with fibromyalgia at age 29. SED rate very high - 50's and CRP 4-5x normal range entire time. Still fibro? If not, any ideas?

Dx with fibromyalgia at age 29. SED rate very high - 50's and CRP 4-5x normal range entire time. Still fibro? If not, any ideas?

You need to see: A rheumatologist or a family physician with good knowledge in autoimmune and connective tissue diseases. These results do not confirm anything, and they are at best nonspecific. However, given an apparent lack of diagnosed infection, they are markers of inflammation often correlated with autoimmune disorders as well as infection. Thanks for trusting in HealthTap. ...Read more

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I'm 23 male my ra factor is 100 positive my ccp is 16 negative, sed rate 12 negative, and crp. 13 negative can high blood fats cause + ra factor?

I'm 23 male my ra factor is 100 positive my ccp is 16 negative, sed rate 12 negative, and crp. 13 negative can high blood fats cause + ra factor?

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, rheumatoid factor is not a specific marker for rheumatoid arthritis. It can be positive in many situations, including recovery from infection. High blood fat per se is not a cause of +RA factor. ...Read more

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I have high CRP 90 and sed rate 100 and iron in the blood 1 6 I have pain in all of my body test in reuma and gastro negative what is wrong with me?

I have high CRP 90 and sed rate 100 and iron in the blood 1 6 I have pain in all of my body test in reuma and gastro negative what is wrong with me?

Have a SPEP done: This is impossible to answer without more info. I would tell you to have a serum protein electrophoresis (spep) done to look for the presence of a monoclonal spike. As you saw a rheumatologist already, I will assume that pmr has been ruled out. ...Read more

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WBC, Platelets, Sed Rate, CRP all remain high and have since 2000. What could be causing this? What should the Drs be checking for?

WBC, Platelets, Sed Rate, CRP all remain high and have since 2000. What could be causing this? What should the Drs be checking for?

Abnormal Blood Study: Without knowing the numbers, it is hard to say. A 16 year history of leuko-- and thrombocytosis, combined with evidence of chronic inflammation, suggests SLE or some other autoimmune disorder. Platelets are usually low in SLE, though. This is a puzzler without further details. Suggest a thorough work up by a specialist in Hematology. ...Read more

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Positive ANA 1.80 spreckled, ALT 7 Low High CRP & sed rate Extreme fatigue, rashes, joint pain, hair loss, mouth sores, migratory arthritis, anemia, etc. MRI Consistent with Proliferative Synovitis (i.e. rheumatoid or psoriatic) Is this lupus or?

Positive ANA 1.80 spreckled, ALT 7 Low High CRP & sed rate Extreme fatigue, rashes, joint pain, hair loss, mouth sores, migratory arthritis, anemia, etc. MRI Consistent with Proliferative Synovitis (i.e. rheumatoid or psoriatic) Is this lupus or?

I suspect so: The low ALT means nothing at all. Get a Coombs' test to see if your anemia is autoimmune, and of course the essential lupus labs -- anti dsDNA, anti-Sm, anti U1RNP, anti-Ro, anti-La. These labs are prone to technical errors. The real question is, "Do we TREAT you? If so, how? " That's why there are rheumatologists and regardless, you need a relationship with a trustworthy specialist. ...Read more

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I have high CRP 90 and sed rate 100 and iron in the blood 1, 6 I have pain in all of my body tests in rheuma and gastro ok what is wrong with me?

I have high CRP 90 and sed rate 100 and iron in the blood 1, 6 I have pain in all of my body tests in rheuma and gastro ok what is wrong with me?

Inflammation!: A CRP of 90, must be mg/liter, which is very high. More important than fibrinogen elevation, the cause for high sed rates, or esr. This is the test that should be followed. Ferritin is moot, since it to is an acute phase reactant. You have serous inflammation. At your age arthritis, or autoimmune disease is likely. Polymyalgia rheumatica would be first. See someone in rheumatology. ...Read more

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SLE pt. SED rate >140 but CRP normal. Dr says I have pleuritis but SED has never been this high. Trying to understand.?

SLE pt. SED rate >140 but CRP normal. Dr says I have pleuritis but SED has never been this high. Trying to understand.?

Unusual: A normal CRP suggests that there is no significant inflammation going on. The SED rate can be elevated when there is anemia or estrogen treatment even without inflammation. In general, I prefer CRP. As for pleuritis, it is a clinical diagnosis and not diagnosed by a lab test. There may be other explanations for this discrepancy but the above is what I can think of. ...Read more

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High sed rate high WBC high crp...low vitd...high micro albumin and high creatnine? . and pain in right upper and right lower quads

High sed rate high WBC high crp...low vitd...high micro albumin and high creatnine? . and pain in right upper and right lower quads

See a doctor!: Hi. I don't know how "high" your values are, but my advice is see the doc who ordered the tests about the results. If you're not satisfied with his/her explanation, get a second opinion. I can think of many bad things this could be, speculating without more information. The internet is no place for your case! Good luck. ...Read more

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Crp was high now normal. Sed rate at 30 suppose to b under 20. Ana + w/spec pattern. Mid bk pain since may. Cbc and metabolic and urine good. Thy ok.?

Nonspecific findings: All these are soft findings that, in and of themselves, mean nothing specially with normal ua, cbc, and met panel. Speckled pattern of ANA unless a hight value is not of significance. Mild back pain may or may not be of consequence. If overlies the kidneys, may need an ultrasound to rule out kidney stone. Musculoskeletal? Watch the way you sit or lie down watching tv or standing at kitchen sink? ...Read more

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Sle patient. Diangosis with pleurisy and pericarditis. Very high CRP and sed rate but is now normal. If inflammation is norm why am I still having symptoms?

Recovery time: The CRP and ESR are just general markers for inflammation and may not reflect local inflammation. In addition, even if the inflammation has stopped, the damaged tissue needs time to heal. ...Read more