Doctor insights on:
Elevated Protein C Activity
How low would a patient's protein C activity level has to be before an OB will put her on Lovenox (enoxaparin)? If pt also MTHFR homo C677T, does it change the tx?
Tested for anti cardiolipin IgM is negative (0.7) but IgG is positive (54.8) normal range of lupus anticoagulant, protein S and protein C activity help?
Not sure: I am not sure I understand the question. I suspect you are being evaluated for a blood clotting disorder and you have an elevated anticardiolipin IgG. One test however does not make the diagnosis of anti-phospholipid syndrome. ...Read more
I got test back that said my fibringen activity antithrobin III protein c protein c antigen were high watch would that mean thank u?
See below: These are blood tests that we usually do to screen people who we think have a predisposition to have blood clots. By themselves they don't mean anything as normal people can have elevated levels. If you have a strong family history of blood clots or if u have had a blood clot yourself then this test could have significance. The best thing to do would be to discuss with a hematologist. ...Read more
My protein c levels are elevated to 213%. Also my hexagonal phospholipid neutralization came back positive. I had a massive PE and not sure what's up?
You have a tendency: To form clots, it is an autoimmune phenomenon. Stay on anticuagulation and see rheumatologist regularly, you will be OK ...Read more
No: Minimal elevations mean nothing. Reference ranges are set so that a few percent of healthies fall outside on either end. ...Read more
Hi I recently had testing do to a miscarriage. My protein c level was elevated at a value of 202. Also my anti thrombin 3 was elevated value 126. What if any underlying conditions will cause elevation. I have been told to follow up with a rheumatologist.
Autoimmune disorders: There are numerous autoimmune disorders that can contribute to increased risk of miscarriage. In addition there may be abnormal clotting disorders related to protein C & thrombin. A thorough evaluation with a specialist in autoimmune disorders is recommended to avoid a recurrence. Best of luck. ...Read more
Tests for clotting: People whose blood tends to clot excessively can have deep vein thrombosis (clots in veins in the legs or abdomen) or pulmonary emboli (clots that travel to the lungs). A deficiency of protein c or protein s, among other things, can cause excess clotting. Tests for protein c or s are used to diagnose levels of these proteins in the blood. ...Read more
Blood coagulation: Protein C and S work together in regulating the clotting of blood. These proteins are important in controlling the amount of blood clot formation inside blood vessels. Deficiency of either can lead to venous blood clot formation. Deficiencies of both are not that common. ...Read more
Protein S 107% (60-130) Protein C 67%. (70-140) should I be concerned with low protein C results?
All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the results you provided are not a cause for concern.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex. ...Read more
Yes: Combined protein c and protein s deficiencies can occur in one individual who is unlucky enough to inherit both autosomal dominant traits. This is very rare. Care should be taken as to when to check levels of these two proteins since both of them would be low in patients taking warfarin since both are also vitamin k-dependent in their production in the liver. ...Read more
Is there any time gap before coagulation tests like protein c and s to be done after a young stroke?
Yes: "morning after" or emergency contraceptive pills that contain no estrogen do not increase risks of clotting. Plan b one-step, for example, is available without prescription. Some women with clotting disorders opt to use iud's for contraception. A copper iud can be inserted for emergency contraception in women who wish to continue this method. ...Read more
I recently got my blood report. I have c-reactive protein (c.R.P.) positive with 4.8 mg/dl & erythrocyte sedimentation rate 24 and packed cell volume 33?
Inflammation: You are anemic and have inflammation. Check 25-oh vit d level. Anemia could be due to iron deficiency if having heavy periods. That can make you more toxic to cadmium a pollutant that is activated by stress and increases cr-protein. Improve health with healthy food, supplements to prevent deficiency, a good night sleep, mild exercise through the day, and de-stress. See kelly mcgonigal's book. ...Read more
I just received some test results back that said my protein c is high, protein s is low my pai-1 is high, my chloride is high and my co2 is low?
Clot risk.: A high protein c has no significance, only low. A low protein s, like protein c, is a risk for having abnormal blood clots or pregancy complications. Protein c and s cooperate to dissolve blood clots. Pai-1 blocks the clot dissolving pathway, so a high level also is a risk for abnormal clots. A high chloride and low co2 are part of the salts in the blood that are regulated by the kidneys. ...Read more
Protein c defiency venal ulsur. How do take care of this please. It's been two years of open foot sore.
Check veins: Protein c deficiency makes one more vulnerable to getting blood clots, and it sounds like you have a venous ulcer, which may have resulted from previous deep venous thrombophlebitis. Check with a phlebologist in your area by going to www. Phlebology. Org. Ultrasound of the leg veins will be helpful in evaluating incompetence of superficial leg veins, and fixing this will help you. ...Read more
Is a simple coagulation lab test (PT/PTT INR & Fibrinogen) sufficient to diagnose Protein C, Protein S &/or Factor V leidmen mutation disorders?
Heterozygous for MTHFR, have high Protein C & Fact, VIII. Taking 3mg methylfolate for 3 mo, homocysteine normal. Reason to follow up w. hematologist?
No: Forgive my frankness. Most of us pathologists do not believe in this MTHFR screening being promoted by a lab to physicians worried about liability. A majority of folks test "abnormal" and are then offered questionable vitamin supplements. Reference ranges arbitrarily put several percent of healthies outside; high protein C and factor VIII are not worrisome especially if you feel well. ...Read more
Why are my veins from my arms up through my chest very predominate? I have a protein c deficiency.
What are good protein/vitamin/nutrient rich things to eat before strenuous activity at high altitude?
Wish it was clearer!: Being well hydrated is most important & in a positive calorie state so your body has ready fuel is also critical. Studies examined high protein, high fat, and high carb diets &- while answers vary at very high altitude-a balanced diet is wisest in general. Tiny support perhaps for a 2001 study of daily vitamin c 1000 mg, vitamin e 400 mg, and 600 mg lipoic acid but I opt for Diamox to climb hard. ...Read more
Does a high level of daily physical activity require carbohydrate intake? What about just eating protein?
Must have carbs: Carbohydrates are essential for energy. There are arguments over how many and exactly what type, but generally speaking, a moderate amount of complex carbohydrates should be a part of at least a couple of your meals each day. Those that try to exercise without carbs in their diet often have shortened or poor workouts. ...Read more
Is it okay to go on a low-carb and high protein diet, with 1 hour of physical activity, to lose weight and be healthy?
Won't harm: Low carb, high protein diets are the basis of several diets such as atkin's diet. It is important to note that the key to weight is not losing weight but maintaining as close to ideal weight as possible over time. Significant changes in diet that can not be sustained over the years is likely to lead to a weight loss/weight gain roller coaster that is not conducive to good health. ...Read more
Having protein in urine due to lupus. Does drinking protein shakes (to gain muscle for exercise) affect the protein activity?
Presence of protein in the urine is usually suggestive of underlying kidney disease. When the kidney filters get damaged the protein from blood tends to leak into the urine and causes further damage.
most common causes are diabetes and high blood pressure.
Please make appointment to see a kidney specialist. ...Read more
Need more info: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, An M spike may be a benign monoclonal gammopathy or a marker for a bone cancer. You ought to consult the doctor who ordered the test as more information is needed to assess this finding. ...Read more
Mild hypergammaglobulinemia polyclonal. What causes it and elevated igg. All other proteins are normal.
See details: These results have no clinical significance. Why was the test ordered in the first place? ...Read more
Go for it!: Please submit a clear & specific question about alpha feto proteins. Clarify and re-ask. ...Read more
Can fasting cause an elevated (4.2) globulin level? What about fasting followed by a high protein meal before the test?
I realise that these markers aren't specific but wouldn't most advanced cancers cause elevated Sedimentation rate and C-reactive protein?
No: Nice to be able to help once again, Matt. The sed rate and especially the C-reactive protein result from the liver pumping out extra large amounts of a couple of particular proteins that are stimulated by very particular things that are often produced in inflammation and seldom in pure neoplasia. Forget most (not all) of what you've read about "immune response to cancer" as myth. Best wishes. ...Read more
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