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Doctor insights on: Elevated Maternal Serum Alpha Fetoprotein

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With cirrhosis what is the relevance of elevated alpha fetoprotein?

With cirrhosis what is the relevance of elevated alpha fetoprotein?

Cancer screen: People with cirrhosis have a higher risk of primary liver cancer. The blood test for alpha-fetoprotein is a marker or screening test for liver cancer. The other method often used is periodic abdominal ultrasound. ...Read more

Serum (Definition)

Serum is the component of blood that does not contain cells or clotting factors. It does contain electrolytes an ...Read more


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What can cause an elevated alpha fetoprotein level?

What can cause an elevated alpha fetoprotein level?

Different diseases: In pregnancy, elevated alpha fetoprotein levels in a woman's serum can indicate fetal abnormalities, like neural tube defects (spina bifida) or ventral wall defects like omphalocele. Outside pregnancy the levels can be elevated in liver cancer or cancer of the germ cells (ovary, testes). ...Read more

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Can dehydration cause slightly elevated alpha fetoprotein?

Can dehydration cause slightly elevated alpha fetoprotein?

Dehydration and labs: Dehydration can raise some blood values. Most notably, sodium, chloride, BUN and creatinine are elevated due to less water in the blood. Likewise, Alpha fetoprotein can also be elevated and you would have to see how how the elevation is and how the severe the patient's dehydration was at the time the blood sample was taken. Ask the physician who ordered the test for her input. ...Read more

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What does an elevated alpha fetoprotein in pregnancy mean?

What does an elevated alpha fetoprotein in pregnancy mean?

Increased tesing: An elevation of the Alpha fetoprotein test should alert your doctor that there may be an increased risk of genetic abnormalities such as down's syndrome in the baby. Pregnant women are offered a more detailed ultrasound test looking for signs of genetic problems & are usually offered an amniocentesis which lets you know the chromosomes of the baby. Down's is also known as trisomy 21. ...Read more

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Testing in pregnancy showed elevated alpha-fetoprotein. What does it mean?

Testing in pregnancy showed elevated alpha-fetoprotein. What does it mean?

Alpha feto protein: An elevation of Alpha feto protein between 15-18 weeks in pregnancy may be asign of a defect in the forming fetal spine( neural tubr defect). It requires a specialized ultrasound imaging to rule out the above possibility. You must speak with your doctor and seek adequate care. ...Read more

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When did alpha fetoprotein testing start?

When did alpha fetoprotein testing start?

1980's: The Alpha fetoprotein test was around when i was a resident physician. The test has progressed through the y ears such that there are four levels measured in the pregnant woman's blood looking for the risk of down's syndrome (trisomy 21), trisomy 18 & neural tube defects like spina bifida. This is called the quadruple screen best measured between 16 & weeks of pregnancy. ...Read more

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What's alpha-fetoprotein (afp) in amniotic fluid?

What's alpha-fetoprotein (afp) in amniotic fluid?

See below: AFP is a protein produced by the yolk sac and liver of a fetus. Since it is in the plasma of the fetus, it can be found in the blood of the mother. ...Read more

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My blood level of alpha fetoprotein is 29. What does this mean?

My blood level of alpha fetoprotein is 29. What does this mean?

AFP=29: Normal range for AFP in 15-18-week-pregnant female is 10-150 ng/ml or mcg/l; normal range in non-pregnant female is 0-40 ng/ml or mcg/l. See chart for interpretation of high or low values (yours is in normal range). ...Read more

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What does a low alpha fetoprotein level mean?

What does a low alpha fetoprotein level mean?

Alphafetoprotein: Very low levels of AFP measured between 16-18 weeks of pregnancy can be associated with chromosomal abnormalities in the fetus, most commonly down's syndrome. Further testing by amniocentesis will rule this out. It may also b a red flag for intrauterine growth restriction and preterm birth. Will need closer observation and testing. ...Read more

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My female friend has an alpha-fetoprotein (afp) number of 20.91 ng/ml . . . What does this mean?

My female friend has an alpha-fetoprotein (afp) number of 20.91 ng/ml . . . What does this mean?

Is she pregnant?: The AFP concentration in maternal serum rises throughout pregnancy and goes to about 220 ng/ml. There should be ...Read more