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Doctor insights on: Elevated Free Testosterone In Women With Ovarian Tumor

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Relationship between high testosterone levels in a male and possible adrenal tumor? Other symptoms of adrenal tumor aside from testosterone levels?

Relationship between high testosterone levels in a male and possible adrenal tumor? Other symptoms of adrenal tumor aside from testosterone levels?

Doubt any: High testosterone levels in a normally-functioning young man probably mean nothing, perhaps a personal variant in the amount of the binding protein. I am most concerned about your pituitary adenoma, which as a prolactin-producer is likely to affect your libido independent of your testosterone levels. Adrenal tumors can produce other androgens but seldom testosterone. ...Read more

Neoplasms (Definition)

"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more


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Can POCS causes both high androgen and estrogen levels if not overweight? Can eating pyhytoestrogens increase breast cancer in women with POCS?

Can POCS causes both high androgen and estrogen levels if not overweight? Can eating pyhytoestrogens increase breast cancer in women with POCS?

PCOS: PCOS can increase androgens in patients regardless of their weight. The effects on Estrogen are less clear as these levels fluctuate and typically would not be tested in PCOS. The LH and FSH levels are checked but not Estrogen. The effects of Phytoestrogens such as soy on the risk of breast cancer are debatable. There is not specific recommendation for PCOS patients to avoid them ...Read more

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Can high Prolactin, high TSH, high FSH and normal T4 levels be associated with an empty sella or a cystic legion in the pituitary fossa?

Can high Prolactin, high TSH, high FSH and normal T4 levels be associated with an empty sella or a cystic legion in the pituitary fossa?

Something odd here: Usually when you have high TSH it is because your thyroid hormone levels are low and yet you report your T4 levels are normal. I would go see an endocrinologist and sit down with him and review with him what's up doc. And that's not a wacky suggestion. ...Read more

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Is moderately elevated androstenedione sign of an adrenal tumour? Testosterone only slightly elevated. Or is it pcos? Polycistic ovaries seen on US

Is moderately elevated androstenedione sign of an adrenal tumour? Testosterone only slightly elevated. 
Or is it pcos?
Polycistic ovaries seen on US

Don't know what a: "moderate" elevation or a "slight" elevation is, but PCOS is the most likely. Discuss potential use of metformin with your doctor, and even adding in spironolactone to lower testosterone. ...Read more

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Do high estrogen levels cause breast cancer in men?

Do high estrogen levels cause breast cancer in men?

IT'S A RISK FACTOR: Prolonged exposure to estrogen is a risk factor for breast cancer in men. Obesity, liver cirrhosis and high alcohol intake can lead to a high estrogen state. ...Read more

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A 40 yr old male with testosterone & cortisol deficiences oestradiol level is 665 (Ref: 10-40 pg/ml) Could pituitary adenoma increase male oestrogen?

A 40 yr old male with testosterone & cortisol deficiences oestradiol level is 665 (Ref: 10-40 pg/ml) Could pituitary adenoma increase male oestrogen?

Perhaps: You have real issues with the estrogen level that you are walking around with, you are at very high risk of stroke and heart attack. Yes, a pituitary tumors, such as a prolactinoma is a very strong possiblity. If you have not already done so, you need to see endocrinologist and you need an MRI of your brain to check your pituitary gland. ...Read more

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Has anyone seen a patient with adrenal insufficiency, intermittent ovarian failure, intermittent glucose intolerance, and thyroid values in normal range? Perhaps also with a pituitary tumor?

Pituitary tumors: You need an endocrinologist to sort this out. A big pituitary tumor (>10 mm) can wipe out other hormones; you could lose some (eg reproductive) but not others. Typically the last to go from a pituitary insult is TSH and acth (thyroid and adrenal), but odd things can occur. A micro tumor does not usually damage the rest of the pituitary, but may produce excess hormone (eg. Prolactin, acth). ...Read more

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23 yrsmri pelvis showed lots of follicles in ovaries. Excessive hair growth. Elevated serum prolactin. Slightly high dhea. Very painful period. Pcod?

23 yrsmri pelvis showed lots of follicles in ovaries. Excessive hair growth. Elevated serum prolactin. Slightly high dhea. Very painful period. Pcod?

Possibly: Pcos does not cause prolactin to be elevated. Talk to your doctor about the meaning of your lab results who can also factor in your medical history and physical exam. The rest of your presentation does seem like pcos. ...Read more

Dr. Alvin Lin Dr. Lin
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Do very low free testosterone levels (below 100) usually go along with infertility in a male?

Dr. Alvin Lin Dr. Lin
1 doctor agreed:
Do very low free testosterone levels (below 100) usually go along with infertility in a male?

Depends . . .: It's possible to have issues w/enough lh or leydig cells such that testosterone is low yet fsh ; sertoli cells are fine so no fertility issues. However, taking testosterone in any shape or form will essentially render you infertile as it will shut down your fsh and thus sperm production. If you need to boost your t and maintain fertility, consider off-label hcg, Clomiphene or tamoxifen. Good luck! ...Read more

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In PCOS patients can high bioavailable testosterone cause high LH, or does the high LH cause bio test to increase? Insulin, total testosterone normal.

In PCOS patients can high bioavailable testosterone cause high LH, or does the high LH cause bio test to increase? Insulin, total testosterone normal.

Testosterone: testosterone production in females in mostly from the theca cells of the ovarian cortex, stimulated by LH from the pituitary. High testosterone may feedback to suppress LH, but not the other way around. The amount of available (free) vs. bound is not directly influenced by LH. ...Read more

Dr. James Lin Dr. Lin
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Low Testostorone, low free T, low SBGH, normal LH, FSH, and TSH. Had increase in T with clomid (clomiphene). Does this rule out pituitary / hypothalamus problem?

Dr. James Lin Dr. Lin
1 doctor agreed:

Here are some ...: Congratulate for improving T with Clomid, (clomiphene) but need to correlate T-level with clinical low-T-related Sx. This indicates HPT(hypothalamus-pituitary-testicular) axis still functions but suggests some dysfunction in hypothalamus, which has been observed in those having taken CNS-effecting drugs such as opiates for a long duration. Nonetheless, you're in best possible care and continue its use. Best .. ...Read more

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I have severe hypogonadotropic hypogonadism with very low testosterone levels caused by pituitary adenoma (prolactin). Is fertility still a possibility or not?

I have severe hypogonadotropic hypogonadism with very low testosterone levels caused by pituitary adenoma (prolactin). Is fertility still a possibility or not?

Yes.: Medication, surgery, or even radiation. Medication sometimes fails and surgery can lead to other issues and even affect vision. Some of these tumors are not resectable fully with out causing issue(s). Once the lesion is controlled, the key is having the situation reviewed by your endocrinologist to see what needs to be done to allow normal fertility. ...Read more

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LH and FSH normal at 2 range (2-9). Prolactin 18 high end of normal. Low T , low sperm count. That could be secondary hypogonadism or pituitary tumor?

LH and FSH normal at 2 range (2-9). Prolactin 18 high end of normal. Low T , low sperm count. That could be secondary hypogonadism or pituitary tumor?

Endocrinologist: If ur T is truly low, then FSH and LH should be towards the upper limit of normal (near 9); the fact that it is not could mean secondary hypogonadism, which has many causes (including a tumor). However, a brain tumor should cause some symptom eventually - headaches, vision trouble. U may need to just repeat the blood test to put ur mind at ease. Talk to an Endocrinologist w/ ur symptoms & lab resu ...Read more

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Low testosterone in a 25 year old female (pellets suggested). Random lactating but prolactin levels normal. Other symptoms suggest cushings.

Low testosterone in a 25 year old female (pellets suggested). Random lactating but prolactin levels normal. Other symptoms suggest cushings.

See and endocrinolog: Testosterone is not normally replaced in women, especially young women as no one knows the best dose to give w/o significant side effects. Cushings could be possible but some symptoms are vague, if concerned, see endocrinologist for testing for cushings and although pellets are available, they are not the most common form of hrt, requires a minor surgery and can be hard to remove. ...Read more

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What does "feminizing" hormones mean? Male with high dhea, e1, e3 , progesterone and low cortisol. Testosterone lower limits

What does "feminizing" hormones mean?  Male with high dhea, e1, e3 , progesterone and low cortisol. Testosterone lower limits

Feminizing hormones: 38 M from PA asks" what does feminizing hormones mean". Have you ever heard of Google? Give this a try. In short they make a man into a woman-but mostly makes boobs get bigger and hurt and Increase risk of blood clots.. Need more information including picture and what you are taking. Happy to consult. ...Read more

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How to treat high LH in pcos? All hormones est, test, prog, dh, sb, and ovary size, insulin normal. Corp leut once saw with many cysts but not always.

How to treat high LH in pcos? All hormones est, test, prog, dh, sb, and ovary size, insulin normal. Corp leut once saw with many cysts but not always.

You don't: Goal of treatment is not to treat high lh. It is to regulate the periods in women not trying to get pregnant, help with fertility in women who are, improve Insulin resistance and treat excess hair growth and hair loss and prevention of diabetes and high chol. High lh is just a marker that pcos may be present but is not used for diagnosis. ...Read more

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Does prolactin level of 18 suggest pituitary tumour? Ive low T but normal FSH and LH. Low sperm count. Is 18 which is the high normal indicate tumour?

No: Folks with pituitary tumors normally have much more abnormal values. I would not be worried about pituitary tumor with the symptoms and lab values you describe. Hope this was helpful. Best of luck. Dr R ...Read more

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50 yr old F, total Testosterone is 51, T Free 12.6, DHEA normal. Doctor is concerned about Ovarian Tumor. Are age and levels indicative of OC?

Testosterone: Testosterone levels usually start dropping around the time of menopause. The DHEA was ordered to help exclude adrenal growths. Your PCOs can cause a mild elevation in both total and free testoterone. ...Read more

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20 year old girl free testosterone level is 2,0 is it normal? ( 2,6-5,5 pg ml written as norma for fertile woman )

Probably normal: Hi. That's probably normal. I'm not sure what you're really trying to find out. Why did some doctor measure your free testosterone? Usually that's to work up hirsutism (male pattern hair growth) and/or irregular/absent periods. If it was for a low libido workup, it may be an issue. Are you cycling normally? Free testosterone will vary with your cycle, and repeating it may be normal. Need more info ...Read more

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I have PCOS my free testosterone came back elevated, total serum test. was normal (25). why is this and how do i treat it?

I have PCOS my free testosterone came back elevated, total serum test. was normal (25). why is this and how do i treat it?

T bound and free: Testosterone comes in two forms "tied up"(bound) and free(liberated). The bound form often sends out more free T which may be coming from the ovaries and not from the blood stream. What is important to you is that the TOTAL value was normal. ...Read more

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How can I increase my low shbg coupled with high free testosterone levels? I'm a young female, lean, active, & suffering from a surge acne severity.

OCPs: Hormonal therapy with an estrogen containing oral contraceptive will do exactly what you are looking for. Ortho tri-cyclin and Yaz (drospirenone and ethinyl estradiol) are fda approved for acne and are good choices. ...Read more

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I have very high levels of 17 ketosteroids, as a woman. my menstruation appears irregular. one month yes, one not. my free testosterone is ok, and the?

I have very high levels of 17 ketosteroids, as a woman. my menstruation appears irregular. one month yes, one not. my free testosterone is ok, and the?

Irreg menses: High ketosteroids may indicate an adrenal malfunction. Such can inhibit regular ovulation, and hence cause irregular menses, since a "true" menstrual flow depends on ovulation to occur approximately 14 days prior to menstrual flow. Ask your healthcare provider to refer you to a reproductive endocrinologist. ...Read more

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20 year old female,had facial laser but hair got thicker.I have also frontal hair thining . my labs : DHEAS 484.1ug/dl,free testosterone 0.021 nmol/L.

20 year old female,had facial laser but hair got thicker.I have also frontal hair thining . my labs : DHEAS 484.1ug/dl,free testosterone 0.021 nmol/L.

Endocrinologist: If you have male pattern hair loss and hair growth, an endocrinologist is best qualified to evaluate and treat you. He/she can interpret your test results and order any other appropriate tests for diagnosis and then treat If needed. ...Read more

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Borderline ovarian tumor. So can we wait to have kids?

Borderline ovarian tumor. So can we wait to have kids?

No if malignent: Fundamental concept , malignancy, should be treated first, may be ovum ( egg ) could be harvested from other ovary. ...Read more

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What can I do to distinguish between period and ovarian tumor blood?

What can I do to distinguish between period and ovarian tumor blood?

Is no ovarian blood: menstrual bleeding occurs due to sloughing of lining of uterus secondary to hormonal changes on a monthly basis. Ovarian tumors do not bleed. They can spread to uterus but that is in the metastatic phase of disease when spread has probably involved omental fat pad and is secondarily associated with peritoneal ascites.. ...Read more

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I had a borderline malignant ovarian tumor that was mucinous. Would that mean it was pre-cancerous?

I had a borderline malignant ovarian tumor that was mucinous. Would that mean it was pre-cancerous?

It's cancer but...: On the other hand, it's not very aggressive. I hope it's out. Your gynecologist can tell you the odds of its staying gone for the rest of your life. ...Read more

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What to do after diagnosis of hypermenorrhea and ovarian tumor?

What to do after diagnosis of hypermenorrhea and ovarian tumor?

Bleeding and tumor: You need a complete work up including: history, physical, ultrasound and tumor markers. The size of the mass is key. ...Read more

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My friend has an ovarian tumor and pelvic cancer what should she do to ease up the pain ?

My friend has an ovarian tumor and pelvic cancer what should she do to ease up the pain ?

Resect if possible: If the ovarian lesion is associated with a pelvic mass they are probably related and require biopsy. Once cancer is defined it does require surgical debulking totally or to a minimal lesion less than 1 cm. to allow for the proper response to chemo. Omentectomy always follows with a debulking procedure. ...Read more

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What does ovarian tumor marker score 13 mean?

What does ovarian tumor marker score 13 mean?

CA125: A ca125 value of 13 is normal. The trend of the ovarian tumor marker is more important over the course of few months rather than one absolute value. ...Read more

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What is the definition or description of: Borderline ovarian tumor?

What is the definition or description of: Borderline ovarian tumor?

It is low grade Canc: It is a slow growing(low grade) cancer of the ovary which is diagnosed in a small percent of cases. It does not seem to cause serious problem for many years. It also doe snot respond to any chemotherapy. The key is to ovoid over-treatment once this diagnosis has been established and confirmed. ...Read more

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What is difference bettwen symptoms of benign and malignant ovarian tumor?

What is difference bettwen symptoms of benign and malignant ovarian tumor?

Not much: There usually aren't many symptoms to tumors on the ovary whether benign or malignant. Malignancy is associated with weight loss, night sweats and fatigue. ...Read more

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Borderline ovarian tumor removed. Now pelvic pains. Has anyone surviedd this?

Borderline ovarian tumor removed. Now pelvic pains. Has anyone surviedd this?

Yes: The tumors are what was described; borderline. Almost all will survive with no adjuvant therapy at all. ...Read more

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Is it true that an ovarian tumor have the same effects as an ovarian cyst might?

Possibly: An ovarian tumor is solid and will continue to grow. However an ovarian cyst is from an egg cell that did not rupture. You may have pain, irregular bleeding or other symptoms with both, so you should see your gynecologist this week to rule it out. ...Read more

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I was recently diagnosed with a 5cm borderline malignant ovarian tumor. Is borderline malignant mean it's not cancer?

I was recently diagnosed with a 5cm borderline malignant ovarian tumor. Is borderline malignant mean it's not cancer?

It's cancer: However, it's unlikely to harm you. Different physicians may sugar-coat or say "barely cancer" or "not really cancer" but the bottom line is that I'm glad it's out or there's a fair chance it would have killed you. Read online about the statistics but if you were assured, "no spread", you've got 95%+ of it not killing you. ...Read more

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Can a small, solid, ovarian tumor still rupture or twist? I'm experiencing pelvic pain and am wondering if this is the cause.

Unlikely: It has to be over 5 cm in size before leakage becomes a consideration. You can get yourself rechecked by your gynecologist who can verify it with an ultrasound or mri/ct scan. ...Read more

Dr. Alvin Lin
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Dr. Alvin Lin
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