Doctor insights on:
Elevated D Dimer Cancer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Not really: D dimer is a marker of clotting. Blood clots in the legs and lungs are associated with elevation. It will also go up with injuries and surgery. Blood pressure may go up as a complication of a blood clot in the lungs or because of the injury or surgery, but elevated BP should not cause increase in d dimer, or vice versa. ...Read more
Total ck, sed rate, ana, ip ace, serum protein panel normal but gamma globulin (.6) cortisol am (30.8)
Hx of low vit d and K.
What could this mean?
Not much-: An important thing to remember is that lab results are not useful unless there is a clinical context. Advice is based on focusing on the patient, not the numbers. Though you mention a history of low vit D and K, did symptoms exist when the labs were drawn? Why were they drawn in the first place? Otherwise, it is best to ask your ordering doctor what the results mean. ...Read more
What causes elevated calcitriol (108.5 pg/mL) with elevated serum Ca, normal PTH. No granuloma disease.
Measure 25(OH)D: Calcitriol, 25(OH)2D, is usually elevated in granulomatous diseases such as sarcoidosis, in lymphomas or in primary hyperparathyroidism, as you suggest. Calcitriol is quite influenced by intestinal absorption of calcium; 25(OH)D is the vitamin D metabolite usually measured (not DI-hydroxy/2D). Add a 25(OH)D measurement & work with your doctor to pursue the other causes of hypercalcemia. Good luck! ...Read more
Possible: Please note that cea is just another tool we have and as such it is not perfect. Many patients have elevated cea and have no cancer and many others have clinical and x-ray evidence of active cancer and yet their cea is normal. Such tumors just don't produce cea and in those cases, the test is useless. No test is infallible. ...Read moreSee 1 more doctor answer
Seek cause: Vitamin d deficiency is very common today & may explain the high alk phos in an adult; it's usually due to misguided "healthy" lifestyles avoiding sunlight and vitamin-d enriched dairy products. Anemia is more worrisome and always requires a real medical workup; nutritional iron deficiency is rampant in our world but other causes must be sought as well. Good luck & stay proactive. ...Read more
CA-19-9, hs, CRP, ESR and CEA levels. Are these typically elevated in pancreatic or gastric cancer??
Tests CA pancreas: 21 M LA US asks CA-19-9, hs, CRP, ESR and CEA levels. Are these typically elevated in pancreatic or gastric cancer?? ANS: if by typically you mean more than 50% of the time then No. I would discuss each with your Dr who ordered these and see how the numbers should be interpreted in your specific situation. ...Read more
What could cause a persistently elevated serum calcium (10.4), vitamin d deficiency (19.7), but low pth (12)?
Vitamin D: Of 19.7 is a disaster since it should be between 60 and 80. I suspect that is the bottom line cause. ...Read more
Smoke/alco free 15 months. New labs show high ldh + lipase; borderline low amylase + globulin. Already ruled out ibd, celiac, mono, hep, hiv, tb, lupus, ra. July ct=normal liver/kidneys/panc. Cancer?
MRCP: Looks like you have pancreatitis, but if you have not had alcohol, need mrcp to see if there any pancreatic duct abnormalities. Need more info, were you drinking before and did you have multiple pancreatits before? Mrcp followed by eus would help. Ercp may be needed once acute episode is resolved, or if you find any stricture in the duct. ...Read moreSee 1 more doctor answer
What is implication homogeneous ANA 1:320, compliment 4 high 44, sed rate and c-reactive protein often elevated and vitamin d low?
Replace vitamin d: Vitamin d deficiency is very common. You need vitamin d to absorb calcium from the intestines. When you don't have enough vitamin d, in order to keep your blood calcium levels normal, your make more PTH to pull calcium from the bones and that raises the alkaline phosphatase. Replacing vitamin d should normalize all the tests. ...Read more
Showing elevated d dimer.1-.57, 2, one month later 0.98. No pe present after ct. Wide RDW and elevated neutrophils, w/ norm wbc. Any clue?
Docs overlooking lymphoma? Months w/ab pain, rectal blood (cscope ok), lymph pain, non-healing acne, episodic fuo. Neg mono test. Latest labs = high ldh, high lipase, low globulin, pos for atyp wbcs
.: I'm not exactly sure what you mean by lymph pain. But if you are having episodes of fevers and chills, unexplained abdominal pain for months, high ldh, this could warrant a ct scan with contrast (if kidneys okay) to look for a cause. Could be lymphoma but most probably not as lymphoma is not that common. Talk to your doctor. ...Read moreSee 1 more doctor answer
Would Waldenstrom macroglob/mult myeloma definitely show abnormal total protein or abnormal a/g ratio? Protein 7.7, alb 4.7, alb 3.0,a/g ratio 1.5
Not necessarily: About 20% of Multiple myelomas only produce light chains and may not alter serum proteins measurably. There are specific tests for myeloma and Waldenstrom. See this site for more info: http://www.mayoclinic.org/diseases-conditions/multiple-myeloma/basics/definition/con-20026607?mc_id=google&campaign=294429041&geo=9011165&kw=%2Bmyeloma%20%2Bmultiple&ad=90615336761&network=s&sitetarget=&adgroup=21734771441&extension=&target=kwd-30051974370&matchtype=b&device=c&account=1733789621&placementsite=enterprise&gclid=CLec4sjU5swCFYIlgQodY8QHAQ ...Read moreSee 1 more doctor answer
Chronic osteomylitis, bone marrow biopsy normal, jak-2 mutation negative, erythropoitin level normal, s.Ferritin level 5 but hb.17.8.What is its reason ?
Many possibilities: Your question is why your hemoglobin is at the top-of-normal (or maybe a tiny bit above) for a person of your age and gender. I'm much, much more concerned about your chronic osteomyelitis. I'd consider a right-to-left cardiac shunt, osler-weber-rendu lung shunt, sleep apnea, high-affinity hemoglobin, an obscure mutation. It's not dangerous in itself & could "just be you.". ...Read more
Testing for AL amyloid. SPEP shows no M-spike but mildly elevated total protein & A/G ratio (2.7) due to high albumin. Globulins well within normal range. Worrisome? Serum/urine IFE &marrow biopsy ok, but elevated free K/L ratio due to low lambda.
D-diner is a breakdown product from blood clots. It can be found elevated in certain conditions like pulmonary embolus (blood clot which travels to the lung) deep venous thrombosis (blood clot in deep vein of legs usually) and disseminated intravascular coagulation (diffuse clot formation from severe infection which ...Read more
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