Doctor insights on:
Elevated Ca 125 Ovarian Cyst
Hi, I'm 48 yo, have endometriosis, ovarian cysts, uterine fibroids, pre-menopausal. CA 125 was around 200's then 159 the last one was 210 any concerns?
Likely, no: CA 125 is not recommended as a screening tool for ovarian cancer when used in risk-based stratification. Meaning, assuming that your mom or sister didn't get diagnosed with ovarian cancer. Normal for women with endometriosis to have elevated CA-125. It sounds like your doctor has done Ultrasound to evaluate ovaries as well. Your MD knows your history and risk, likely this CA-125 level is normal ...Read moreSee 1 more doctor answer
A cyst is a structure or mass that consists of a cellular lined sac. It is typically filled with fluid but may be filled with solid material. It can be congenital, traumatic, or acquired. They may develop nearly anywhere in the body and usually require complete excision for eradication or they are likely to recur. Fluid filled sacs that are not cellular lined ...Read more
What does it mean when you have mildly elevated ca 125? I have a 15cm ovarian cyst. Does that mean its cancerous?
Nothing out of..: ...Context. Ca.125 is used to follow up response to treatment in patients with cancer of the ovary but a slightly elevated level can come from non malignant causes (and it can be normal even if there is cancer). It is not considered a screening test. Whoever ordered it probably had very valid reasons to do so and i'm sure he/she can explain its implications to you in the proper context. Best 2u. ...Read more
7 CM ovarian cyst, ca-125 levels elevated (48), roma score & all blood tests good. Previously had nasopharyngeal cancer. Recurrence or endometrioma?
Likely endometrioma: At your age, ovarian cancer would be exceedingly rare. Ca-125 levels can be elevated in young women for a variety of reasons that have nothing to do with cancer. Nasopharyngeal cancer and ovarian have no relation to each other. Your doctor should tell you what features or characteristics the ovarian cyst has, this will tell you what kind of cyst it is. Good luck! ...Read more
Ask MD ordering test: If there is a history of ovarian cysts and/or abnormal test, a woman definitely needs to be seek input from a specialist or subspecialist in gynecology. That is important to receive their interpretation and recommendations for now and the future. At some point she might need to be evaluated further. Rarely cancer can occur and can be suggested by imaging, so it might be ordered in some cases. ...Read moreSee 1 more doctor answer
Maybe: Talk it over with your doctor. Things to consider are 1) your age and menopausal status, 2) previous history of endometriosis, 3) size of the mass, 4) ultrasound appearance, 5) duration of the problem., 6) family history of ovarian cancer. Remember that ca-125 may be elevated in many benign conditions, as well as ovarian cancer. ...Read moreSee 1 more doctor answer
Possible?: Either way, you definitely need to see your GYN or GYN oncologist soon. ...Read more
Ca-125 (cancer antigen 125 or carbohydrate antigen 125) is a biomarker/tumor marker for ovarian cancer (etc); however, it is not sensitive or specific enough to use as a screening test. Also, a uk study showed that treating based on ca125 level did not improve outcomes. "125" comes from the 125th attempt to develop a marker. It was introduced by bast ...Read more
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