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Doctor insights on: Elevated Ca 125 Levels After A Hysterectomy

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CA 125 level in a 70yr woman who had hysterectomy with removal of ovaries+Fallopian tubes=341U/ml. Possibillity? Waiting for results of pelvic+abd u/s.

CA 125 level in a 70yr woman who had hysterectomy with removal of ovaries+Fallopian tubes=341U/ml. Possibillity? Waiting for results of pelvic+abd u/s.

Waiting is hard: Although it's hard to wait, your doctor is evaluating you for possible abdominal or pelvic cancers which can show up even after removal of the uterus, tubes, and ovaries. They may also recommend a CT (cat scan) or PET scan If the u/s isn't helpful. Best wishes for good results! ...Read more

Dr. Ronald Krauser
128 Doctors shared insights

Ca125 (Definition)

Ca-125 (cancer antigen 125 or carbohydrate antigen 125) is a biomarker/tumor marker for ovarian cancer (etc); however, it is not sensitive or specific enough to use as a screening test. Also, a uk study showed that treating based on ca125 level did not improve outcomes. "125" comes from the 125th attempt to develop a marker. It was introduced by bast ...Read more


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What makes uyou ca125 go up I’ve had a total hysterectomy?

What makes uyou ca125 go up I’ve had a total hysterectomy?

Ovaries: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that, CA 125 is a screening test for ovarian cancer, albeit not a good one. If you still have your ovaries, that may be the cause of elevated CA 125. you may visit this site for more info:
https://www. Mayoclinic. Org/diseases-conditions/ovarian-cancer/expert-answers/ca-125/faq-20058528 ...Read more

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Hi I had a total hysterectomy 7 months ago my doctor checked my ca125 and it is 48 I am 35 y?

What is your Questio: Please ask a question, so we can help clarify your concerns. Ca125 can go up due to many abdominal conditions causing irritation, inflammation or infection. A value like yours is not of much concern to me. You need to ask your doctor why she checked it in the first place? She must have had some reasons to do the test...So she can address it better than I can. ...Read more

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I am 49/post menopausal, I have an 11cm cyst on my right ovary, CA-125 test normal. He wants full hysterectomy, I am unsure. Scared. Thoughts?

I am 49/post menopausal, I have an 11cm cyst on my right ovary, CA-125 test normal. He wants full hysterectomy, I am unsure. Scared. Thoughts?

It depends!: There is some concern that a large cyst in the ovary can be or become cancerous. So removal is often advised. But if you prefer, you can be monitored with serial physical exam and Ultrasound examinations at 6 to 9 month intervals and delay surgery unless the cyst continues to grow or become more complex like showing solid components inside the cyst.. ...Read more

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Complex left pelvic cyst 5cm. Previous hysterectomy ovaries remain. Blood test s oestradiol 2768 pmol/l, ca125 7 iu/l.What are causes, what is treatment

Complex left pelvic cyst 5cm. Previous hysterectomy ovaries remain. Blood test s oestradiol 2768 pmol/l, ca125 7 iu/l.What are causes, what is treatment

More information: Complex cysts in postmenopausal women often need surgical removal. Very specific treatment options in individual cases need to be managed one on one with your and your doctor. There is not enough information to provide a definitive answer. ...Read more

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Complex ovarian cyst, told need complete hysterectomy & need 2 see oncologic gyn. Is this standard or should I worry? Also sent 4 ca-125 & CEA tests

Complex ovarian cyst, told need complete hysterectomy & need 2 see oncologic gyn. Is this standard or should I worry? Also sent 4 ca-125 & CEA tests

Complex Ovarian Cyst: It is not uncommon for a doctor to be cautious and have you seen by a gyn oncologist with a complex ovarian cyst. Most ovarian cysts are benign but some can be cancerous. The size and ultrasound appearance of the cyst as well as the results of the blood tests may raise or lower the suspicion of cancer. It might be best to ask your doctor what they are thinking because they have those details. ...Read more

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70 yr woman who had hysterectomy with removal of ovaries & uterus, diagnosed with congestive heart failure, liver enlarged+abd ascites. CA125= 341.Why?

70 yr woman who had hysterectomy with removal of ovaries & uterus, diagnosed with congestive heart failure, liver enlarged+abd ascites. CA125= 341.Why?

No explanation: One reason that CA125 is such a poor cancer screen is that a great many healthy people run relatively high levels for no apparent reason.. IThe key is managing her underlying illness if at all possible. I trust that cause has been found and is not tumor. ...Read more

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Does an elevated ca 125 level always indicate that ovarian cancer is present?

Does an elevated ca 125 level always indicate that ovarian cancer is present?

No: Ca-125 may also be elevated in other cancers (i.e. Endometrial, fallopian tube, lung, breast and gastrointestinal cancers.) it can also be elevated with endometriosis or any inflammatory condition in the abdominal area. ...Read more

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My ca125 levels are slightly elevated and there is a solid mass on my ovary, should I be concerened that it is ovarian cancer?

Depends: Ask your gyn. A solid mass is concerning, but your age, menopausal status, and the ultrasound characteristics are important as well. Elevated ca-125 suggests ovarian cancer, but may be somewhat elevated in many benign conditions, as well, including endometriosis. All of this needs a discussion with your gyn and a possible referral to a gyn oncologist - who are the real experts in this area. ...Read more

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7 CM ovarian cyst, ca-125 levels elevated (48), roma score & all blood tests good. Previously had nasopharyngeal cancer. Recurrence or endometrioma?

Likely endometrioma: At your age, ovarian cancer would be exceedingly rare. Ca-125 levels can be elevated in young women for a variety of reasons that have nothing to do with cancer. Nasopharyngeal cancer and ovarian have no relation to each other. Your doctor should tell you what features or characteristics the ovarian cyst has, this will tell you what kind of cyst it is. Good luck! ...Read more

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Very low LH and FSH levels after partial hysterectomy at 35--why is that?

Normal: If your ovaries were left in place, you are not in menopause, which is confirmed by low FSH and lh. A partial hysterectomy in medical terms means removal of the uterus but not the cervix. Complete hysterectomy means removal of uterus and cervix. Removing the ovaries is separate. ...Read more

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If I have not had a hysterectomy, will soy lecithin granules effect my estrogen levels in a negative way? (1tbsp per day)

If I have not had a hysterectomy, will soy lecithin granules effect my estrogen levels in a negative way? (1tbsp per day)

No: Oral intake of soy products is not likely to effect your overall hormonal balance. Not sure why you would want to take this supplement though? ...Read more

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What should FSH level be if you are on HRT post hysterectomy?

What should FSH level be if you are on HRT post hysterectomy?

Not measured!: If you had a hysterectomy with oophotectomy (which is removal of the ovaries) your FSH will go very high, usually into the 100's. The FSH responds differently in different people to HRT. In some it does not change in others it comes to undetectable. What is important is how you feel not a number! Also, know in situation it is safe and appropriate to be on HRT, see link. ...Read more

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Is it possible for you to still have a hysterectomy with low hemoglobin levels?

Is it possible for you to still have a hysterectomy with low hemoglobin levels?

See details: It depends how low is low. Usually one will be transfused or the anemia otherwise corrected prior to surgery. ...Read more

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Estradio level serum is 50.79 what does it mean I'm 30 years of age I had a partial hysterectomy 4 months ago been having hot and cold sweats?

Estradio level serum is 50.79 what does it mean I'm 30 years of age I had a partial hysterectomy 4 months ago been having hot and cold sweats?

Follow up visit: For highly specific result interpretation it's best to discuss with the ordering physician who can put it in the proper context. If you still have your ovaries then one expect normal hormone production. Your Estrogen level is normal but a doctor would not test Estrogen levels typically when evaluating hot flashes. They would test an FSH level. Looks like your hot flashes are not from menopause ...Read more

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I had hysterectomy 5weeks ago. Last week I started having pain between tailbone and anus. It hurts to sit. Bm's r normal. No straining. Pain level 7?

I had hysterectomy 5weeks ago. Last week I started having pain between tailbone and anus. It hurts to sit. Bm's r normal. No straining. Pain level 7?

How much pain Rx?: I'm wondering a few things. First, why did you have a hysterectomy? Did you have a posterior repair or other surgical procedures? Second did you suddenly stop taking pain meds? Is there an area that you can press on that worsens pain? Infection is a concern with new onset pain of that intensity at this point post op. Nerves can be damaged during surgery as well. Contact your surgeon right away. ...Read more

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What to do if I'm a woman with naturally high testosterone levels (may or may not be due to pcos) and a hysterectomy?

What to do if I'm a woman with naturally high testosterone levels (may or may not be due to pcos) and a hysterectomy?

Nothing unless. . .: Remember that we treat patients, not just numbers so unless testosterone is causing problems, there's nothing to do about a single high result. In fact, there's no reason to check levels unless one is worried that high (or low) T is causing problems. Besides, it's always better to recheck results before starting therapy. Regarding PCOS, exercise & eat right to lower diabetes & heart disease risk. ...Read more

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My mother had hysterectomy 5 months back, is it possible of bleeding and low haemoglobin level after surgery?

My mother had hysterectomy 5 months back, is it possible of bleeding and low haemoglobin level after surgery?

Many possibilities: While it is possible that the low haemoglobin is related to the hysterectomy, most patients recover to relatively normal levels within a few months of surgery. Late bleeding from a hysterectomy is fairly rare. You did not indicate the reason for the hysterectomy. If it was for non-cancer reasons, your mother's haemoglobin should have resolved by now. I would encourage her to have this evaluated. ...Read more

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Diagnosed with Hashimoto 7 yrs ago and had hysterectomy 7 weeks ago. Can a hysterectomy throw off thyroid levels?

Diagnosed with Hashimoto 7 yrs ago and had hysterectomy 7 weeks ago. Can a hysterectomy throw off thyroid levels?

Thyroid levels: Major surgery can have an impact on your thyroid levels. Please consider getting them checked. ...Read more

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My mom age 47 had hysterectomy 5 months back and removed specimen was diagnosed non cancerous, still have low level of haemoglobin 8g/dl, weightloss?

My mom age 47 had hysterectomy 5 months back and removed specimen was diagnosed non cancerous, still have low level of haemoglobin 8g/dl, weightloss?

More tests: Need to understand why she is anemic. Causes could be diet, blood disorder, occult bleeding from the bowel etc
the weight loss maybe related or possibly due to depression
more tests are needed to decide what is going on here. ...Read more

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I recently had a hysterectomy. On HRT and now thyroid levels are low. Can my hormones cause my thyroid to be mistaken for hyperthyroid?

I recently had a hysterectomy. On HRT and now thyroid levels are low. Can my hormones cause my thyroid to be mistaken for hyperthyroid?

Not really: Hormones can raise your total T4 but not your free T4 which is more accurate. If your total T4 is a bit high but your TSH is normal you are not hyperthyroid. Would help to see actual test resutsl ...Read more

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My estradiol level is 376 &estrogen is 870.Had a partial hysterectomy in march they just removed the uterus. What do these levels mean? Any advice please

My estradiol level is 376 &estrogen is 870.Had a partial hysterectomy in march they just removed the uterus. What do these levels mean? Any advice please

Not menopause: Well, first of all you are not in menopause. Estradiol < 28 means menopause. Beyond that, angelique, it does not mean much else. It seems to be a healthy level of estrogen despite your partial hysterectomy. If you want to get pregnant, at that Estradiol level, it may still be possible. If you had the partial hysterectomy because of a fibroid, you want to keep your Estradiol at a healthy level. ...Read more

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Per my blood work, my estrogen level is 7. I got a prscriptn for divigel but my mom had breast cancer 3 yrs ago. Pls advs. Currently in great health for 51. Black female, straight, otr, cdl driver. Hysterectomy 4 yrs ago for fibroids. I get a physica

Per my blood work, my estrogen level is 7. I got a prscriptn for divigel but my mom had breast cancer 3 yrs ago. Pls advs. Currently in great health for 51. Black female, straight, otr, cdl driver. Hysterectomy 4 yrs ago for fibroids. I get a physica

I: I share your concerns. I do not know what symptoms you are having that you were prescribed Divigel for, but I assume that you are having menopausal symptoms that you are suffering from. My concern with you would be your family history of breast cancer. In addition, there is increased cardiovascular risks in women over 50 and in women who are overweight. I am very concerned that you could have consequences from taking this medication, so please discuss your risk factors with your doctor. My concern with herbal medications is that they carry the same risk with their estrogen-like substances as regular estrogen, so the herbal medication or bio-identicals have not been proven safe in large peer-reviewed studies either. There are other non-hormonal medications that can help menopausal symptoms, such as neurontin, (gabapentin) but there are several others that you can read about or ask your doctor about as well. ...Read more

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Should I have a hysterectomy? I have had 6 blood transfusions in 7years. I am 33yrs old with one pregnancy/one child. I have symptomatic uterine fibroids and iron defiency anemia. My blood levels normally run between 6.9 and 7.3. The lowest has been 5.8

Should I have a hysterectomy? I have had 6 blood transfusions in 7years. I am 33yrs old with one pregnancy/one child. I have symptomatic uterine fibroids and iron defiency anemia. My blood levels normally run between 6.9 and 7.3. The lowest has been 5.8

Short answer no: Losing your uterus at such a young age will likely have negative consequences which are completely avoidable by undergoing uterine fibroid embolization (ufe) instead. Your uterus is important to you psychologically, sexually, and there is increased osteoporosis and heart disease risks with hysterectomy. I'd find an interventiomal radiologist with particular experience in ufe and keep your parts! ...Read more

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What does ca 125 level 600 mean?

High: It's quite elevated, why was it done? Your doc needs to discuss this results with you in the context in which it was ordered. ...Read more

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Can Lyme disease cause an elevated CA125 reading?

Unknown: At this point in time there is a lot of discussion about this topic and many who feel there may be some association but there has been no known proof of an association of Lyme disease and an elevated CA 125. This is still being researched and nothing that can say a definite cause and affect. Hope this helps. ...Read more

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Should I be concerned about elevated ca-125 of 132 if I have a history of benign cysts?

CA-125: This marker is quite non-specific for cancer, particularly in pre-menopausal women. Any things that irritate the lining of the abdomen (such as cysts, endometriosis, and non-ovarian things as well) can prompt elevations in the range you have noted. Other means of screening for cancer however are also imperfect. If you are at high risk, other follow-up may be needed. ...Read more

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How concerned should I be if my ca125 level was not ordered this year?

How concerned should I be if my ca125 level was not ordered this year?

None to minimal: If the ca-125 was going to be used simply as another blood test for example in a yearly physical, you should not be terribly concerned at all. My answer is different however, if you have a history of a disease such as ovarian cancer and that it should be checked. I also might order it if you have a strong family history of ovarian cancer for example. If not you should not be concerned. ...Read more

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Ca125 level is a marker for which tumor?

Ca125 level is a marker for which tumor?

Ovarian: It is neither sensitive nor specific for screening. However, its recurrence after removal of a tumor that produces it suggests recurrence. ...Read more

Dr. Jeff Livingston
1,882 Doctors shared insights

Hysterectomy (Definition)

The entire uterus (womb), cervix, the part protruding into the vagina, and ...Read more