Doctor insights on:
Elevated C3 Serum Levels In Lupus Panel
???: I am not sure about a correlation with blood worm and this antibody? Anti-histone antibodies are autoantibodies that are found in 50%-70% of patients with systemic lupus erythematosus (sle), but I am unawre of a correlation with blood worms? Posibly a pathologist may know of a correlation. ...Read more
Inorgan.Phosphate0.77, serum total protein63, serum globulin14, all slightly low. Norm. Calcium &albumin.Tsh9.25, known hypothyroidism. Further tests?
Not paradoxical: The problem is that copper can't get out of certain cells. The reason for ceruloplasmin being low is under study; since it carries copper, this metal also tends to be low. Checking serum copper and serum ceruloplasmin as a screen for wilson's misses up to a quarter of cases, especially if the person is already sick with anything. ...Read more
Juvenile arthritis: More important that tests is how the child is doing treat the patients not the tests. ...Read more
What illness could explain ELEVATED C3 and C4 complement serum levels in the presence of angioedema? ANA and Rheum Arth Factor both negative.
In blood work, does elevated gamma globulin (m-spike) often cause the total serum globulin to be elevated as well?
How high?: It's important to know how high the tests were above the normal range (were they clinically significant?). Cortisol is produced by the adrenal glands which is under control by the pituitary. The problem could be either one. Your doctor who ordered the cortisol should be able to tell you the next step of workup. If the tests were indeed very high, you will need more testings before treatment. ...Read moreSee 1 more doctor answer
What could cause/explain significantly (4.5x norm rang)elevated plasma norepinephrine levels in blood test , but normal urinary norepinephrine levels?
Minor mystery: Copper is low because ceruloplasmin is low; most copper in the blood is carried on the protein. Nobody really knows why ceruloplasmin tends to be low in Wilson's, and I hope that you also know that in about 30% of Wilson's patients it is not low at all, making is a very poor screening test. ...Read moreSee 1 more doctor answer
Lab results as follows: ANA w/titre and pattern 1:320 and thyroid peroxidase ab 484.0....Are the two related? Would hashimoto's cause high ANA level?
Testing for AL amyloid. SPEP shows no M-spike but mildly elevated total protein & A/G ratio (2.7) due to high albumin. Globulins well within normal range. Worrisome? Serum/urine IFE &marrow biopsy ok, but elevated free K/L ratio due to low lambda.
Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.
False positive rate: There is 30% or so false positive rate of kappa/lambda ratio in people without MGUS, myeloma or other disorders. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read moreSee 1 more doctor answer
Have borderline low C3 and C4 complement levels and low 1:80 titre positive ANA speckled. With symptoms relating to sle and sjorgrens - atypical ?
Atypical for what?: Rheumatic disease generally requires a cluster of suggestive symptoms which is supported by lab studies. I do not know your symptoms, but your labs are not particularly suggestive of anything. ...Read more
What condition(s) causes someone to have high total serum protein, high albumin, normal globulin and high total calcium levels?
Dehydration.: There are no diseases that specifically increase albumin. Therefore in order to get an elevated concentration there must be a decrease in the amount of water in the system. This would also account for the normal globulin. Calcium is bound to Albumin so that elevated Albumin will elevate your calcium levels as well. ...Read more
No to both: Spot cortisol levels are of limited usefulness. Nobody really knows what to make of C-reactive protein except in a few special cases anyway. ...Read more
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