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Doctor insights on: Elevated Bun In Lithium Toxicity

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What are symptoms of lithium toxicity?

What are symptoms of lithium toxicity?

Lithium toxicity: Lithium can cause nausea, vomiting, diarrhea, dizziness, muscle weakness, and fatigue. Also there can be a fine tremor of the hands or legs, muscle twitches, difficulty walking, slurred speech, nystagmus, and seizures. Management is to reduce dose or temporarily stop the drug. Lithium levels need to be monitored regularly, and kept in therapeutic range (maintenance. 6 - 1 mmol/l). ...Read more

Lithium (Definition)

Chemically, lithium is a light, soft, alkali metal. It's very highly reactive, so that in nature it's only found in compound form. It's useful in batteries. As a medication, Lithium Carbonate and citrate can be used to stabilize mood in people with bipolar disorder. In these people it can help with both mania and depression. Blood level monitoring is ...Read more


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My 14 yo daughter may have some symptoms of lithium toxicity. How can I be sure?

My 14 yo daughter may have some symptoms of lithium toxicity. How can I be sure?

Need a blood test: I assume she is taking lithium? If so, then she needs a blood test asap. Lithium toxicity can be very serious, even life threatening. I would call your doctor/psychiatrist immediately or go to the ER. Also, make sure she is well hydrated in the meantime. ...Read more

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Take lithium 300mgs. Recently started Toviaz (fesoterodine) for bladder problem. Can taking Toviaz (fesoterodine) affect the lithium level. Had trouble with lithium toxicity before?

Take lithium 300mgs. Recently started Toviaz (fesoterodine) for bladder problem. Can taking Toviaz (fesoterodine) affect the lithium level. Had trouble with lithium toxicity before?

Should be safe: No significant interaction between these 2 meds has been found to exist. Always check with your doc if you develop any new symptoms ...Read more

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I may have slight lithium toxicity. Is this worth a visit to the er?

I may have slight lithium toxicity. Is this worth a visit to the er?

Depends: What do you mean by this? If you are having symptoms that are consistent with lithium toxicity then it is very important to do 2 things: hydrate well (i.e. Drink plenty of water) and go to either an er or urgent care center. If you just think you took too many pills by accident but have not symptoms of toxicity, you should be ok but need to check your levels soon and talk to your doctor soon too. ...Read more

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Discontinued 900mgs of lithium abruptly on dr's advice because was toxic. Now, about a month later, am experiencing depressive symptoms, already?

Discontinued 900mgs of lithium abruptly on dr's advice because was toxic. Now, about a month later, am experiencing depressive symptoms, already?

Follow up appt?: When is your follow up appt for a lithium level? It may then be safe to take 300-600mg a day if your level has decreased adequately. Some patients benefit from subtheraputic levels on less lithium, which is safer. Make sure your thyroid function tests and kidney function tests are also checked regularly while on lithium. ...Read more

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Post chronic lithium toxicity and withdrawal left me with terrible crawling sensations all over my body. Is it temporary and is there a treatment?

Unfortunately: I can't be terribly encouraging about this. Typically with chronic lithium poisoning there is a large body burden of lithium that is difficult to treat. Often this discovered with time or a new medication that alters kidney function or causes dehydration, causing the lithium level to rise. The symptoms you describe are not unusual. Treatment is symptomatic as for other peripheral neuropathies. ...Read more

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I'm confused, people say they start u out at almost toxic level of lithium. How come there saying im on a low dose? 300 x2 day. What's high dose then

I'm confused, people say they start u out at almost toxic level of lithium. How come there saying im on a low dose? 300 x2 day. What's high dose then

Lower dose - good: High doses can be toxic, so I believe it makes sense to start with a smaller dose and work one's way up to a therapeutic dose based on blood level and how someone is doing clinically! A high dose would be any dose that is too high for you, based on that! No need to be confused - you would not want toxic side effects! ...Read more

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I took Lithium for 2 days and had to quit cold turkey due to toxicity. 2 other psychs say I've been misdiagnosed. Increase in anxiety, will it go away?

I took Lithium for 2 days and had to quit cold turkey due to toxicity. 2 other psychs say I've been misdiagnosed. Increase in anxiety, will it go away?

This is not the kind: Of question that can be answered with any degree of medical certainty in this forum. I would recommend you address your question to a psychiatrist in person during an office visit. Best of luck. ...Read more

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Can loud ringing in the ear caused by severe lithium toxicity be cured?

Can loud ringing in the ear caused by severe lithium toxicity be cured?

Usually goes: Tinnitus, ringing in the ears, is a known side effect of lithium, usually at toxic levels as you've experienced. Most commonly it abates quickly as the lithium is leered r stopped. Sometimes, it can persist, almost always improving, though. ...Read more

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Went for a long hike, rough terrain. Not in shape. I take lithium. I got overheated, nauseated is this sign of Li toxicity? Had lots of water n shade

Went for a long hike, rough terrain. Not in shape. I take lithium. I got overheated, nauseated is this sign of Li toxicity? Had lots of water n shade

Nausea, dehydration: Nausea can be one of the initial symptoms of lithium toxicity. Getting overheated and dehydrated is often a cause of lithium toxicity. However being on medications like Seroquel (quetiapine) and Lamictal can also make one feel a bit nauseous if dehydrated. It is vital to keep oneself well-hydrated when on meds like these. Glad you are ok now. ...Read more

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Took lithium which helped suicidal thoughts disappear. Lithium toxic and need a different med. Would ziprasidone help? Or latuda (lurasidone)?

Took lithium which helped suicidal thoughts disappear. Lithium toxic and need a different med. Would ziprasidone help? Or latuda (lurasidone)?

Lithium: Lithium can be very helpful if used properly and dangerous if not. Please check this with your doctor. An Endocrinologist would also be helpful as there are many labs that need to be evaluated. ...Read more

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How do you treat persistent severe akathisia like symptoms from Lithium toxicity and withdrawal when benzos and propanolol cause breathing issues?

How do you treat persistent severe akathisia like symptoms from Lithium toxicity and withdrawal when benzos and propanolol cause breathing issues?

More info is needed: Are you in a hospital setting? How bad of a lithium intoxication? . A low dose lorazepam 0, 5mg po q4-6 hours should help. Not sure what breathing problems u refer to, but you'll be monitored. If you are at home and can't take benzos, try a calming, long bath with calming salts, and lavanda oil. Followed by a long walk. ...Read more

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I've only been urinating like twice a day little output I also have pain on right side could there be something wrong with kidney I was toxic w/lithium?

I've only been urinating like twice a day little output I also have pain on right side could there be something wrong with kidney I was toxic w/lithium?

Lithium toxicity?: You do not list any medical conditions associated with lithium use. Assuming your info is correct, acute lithium toxicity usually presents with:
diarrhea
dizziness
nausea
stomach pains
vomiting
weakness
you may also have central nervous system symptoms depending on how much lithium you took:
coma
hand tremors
incoordination
muscle twitches
slurred speech
seizures
please seek medical help asap. ...Read more

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When using lithium is it important to have your bun-creatinine-tsh-and electrolytes checked every 3 months. ..along with the lithium level?

When using lithium is it important to have your bun-creatinine-tsh-and electrolytes checked every 3 months. ..along with the lithium level?

Lithium Monitoring: It is helpful to test BUN, Creatinine, TSH and Electrolytes as Lithium toxicity is closely related to serum Lithium levels, and can occur at doses close to Therapeutic levels.

If Manic Symptoms are in control and functioning in relationships, work and personal life has increased, these Tests can be done every 3 months.

...Read more

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Can chronic Lithium toxicity (6+ months) at levels as high as 2.4 as well as renal impairment cause breathing problems? Why? It is it long lasting?

Can chronic Lithium toxicity (6+ months) at levels as high as 2.4 as well as renal impairment cause breathing problems? Why? It is it long lasting?

Kidneys put water ou: Out. And if it doesn't get out it builds up and eventually accumulates in the lungs causing the sensation of drowning. Bad.
Conditiosn that are not treated often do not get better. ...Read more

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Dehydrated, fever 100.2 lithium inc. To 1200mg 4 days ago. Toxic before on this dose 1.4. RN Retrying therapy. Is fever concerning?

Dehydrated, fever 100.2 lithium inc. To 1200mg 4 days ago. Toxic before on this dose 1.4. RN Retrying therapy. Is fever concerning?

Yes: The problem that fever adds is fluid loss. You become more dehydrated with every breath. The body evaporates water through the lungs to help cool you and that concentrates the Lithium. Drinks losts of cool liquids. I like slussys, but replace the fluids you are losing. Your urine should be about the color of Wylers lemone aid (sorry Wyler) Watch your lithium level closely. ...Read more

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Can a low dose of lithium orotate trigger/cause hypomania in bipolar people? What's the max. Time you can be on it without worrying about toxicity? X

Can a low dose of lithium orotate trigger/cause hypomania in bipolar people? What's the max. Time you can be on it without worrying about toxicity? X

No: From what I can see it may have a dinky dose of lithium and lithium wouldn't trigger hypo mania but the amount in this supplement probably wouldn't prevent an episode either--you can get a blood test and see the amount in your system usual starting dose is around 900mg & therapeutic level is between 0.5-1.5 or 0.6-1.2 depending on the lab above these amounts are toxic levels and below may not be e ...Read more

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I had chronic Lithium toxicity. I still get bad nerve sensations, burning pain, tingling. Every doctor denies permanent damage or withdrawal! Help!

I had chronic Lithium toxicity. I still get bad nerve sensations, burning pain, tingling. Every doctor denies permanent damage or withdrawal! Help!

Unclear: I'm unclear what information you're looking for, please clarify. I'm guessing you just want to be out of pain. First seek out diagnoses. If you aren't getting the answer and are still in pain, discuss these concerns with your primary care doctor.

Also "Full Catastrophe Living" is a great resource for cases like this. ...Read more

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Passing gas: since apr/13, my volume is up 200-400%. High fiber diet. Lithium toxicity undiagnosed 5 yrs. Dosage lowered to 450mg 6 mo's ago. Related?

Passing gas: since apr/13, my volume is up 200-400%. High fiber diet. Lithium toxicity undiagnosed 5 yrs. Dosage lowered to 450mg 6 mo's ago. Related?

Not from Lithium: Your increase in flatus is more likely due to your high fiber diet, rather than lithium. Lithium can cause diarrhea ; loose stools in 20% of patients. That said, high fiber is healthy for your bowels. As long as it's coming out, the gas will not harm you. You could avoid gas-forming foods like broccoli, beans, onions, fermentable fiber, lactose, etc, for a couple of weeks ; then test 1 by 1. ...Read more

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Bipolar 2, anxiety and avoidant pd. Self harm suicidal ideas. Is there med that can tame these heavy ideas and images. Toxic on lithium. No psychiatrist

Bipolar 2, anxiety and avoidant pd. Self harm suicidal ideas. Is there med that can tame these heavy ideas and images. Toxic on lithium. No psychiatrist

With this combo: Of diagnoses - I would really consider working with a both a psychiatrist and a therapist. Unfortunately, there is no one pill that is a guaranteed cure. However, I would recommend combining non - pharmacological treatments wtih psychotropic medications. Take care. ...Read more

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Lithium toxic at 1.66.effects were extreme dizziness. Blind spot right eye. Vision looked cloudy. Felt floating. Saw bugs on wall. Delirum or hallucination?

Lithium toxic at 1.66.effects were extreme dizziness. Blind spot right eye. Vision looked cloudy. Felt floating. Saw bugs on wall. Delirum or hallucination?

See doctor ASAP!: I hope you are sharing with us the aftermath of taking too much lithium and have been seen by your PCP. Your description of visual hallucinations and not in your body means you still need to be under emergent medical supervision. So you don't injure yourself or others. You should not be driving or doing anything requiring using machinery, and have 24 hour care in a hospital ER, under observation. ...Read more

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I take 900mg of lithium. Just had gallbladder out yesterday, doc gave me norco (hydrocodone and acetaminophen) and 600 ibprofrin so 4x a day 1800mg ibprofrin make lithium toxic??

I take 900mg of lithium. Just had gallbladder out yesterday, doc gave me norco (hydrocodone and acetaminophen) and 600 ibprofrin so 4x a day 1800mg ibprofrin make lithium toxic??

No worries: Norco (hydrocodone and acetaminophen) and ibuprofen should not react with lithium. Take the pain medication only if you need it! If you can tolerate mild discomfort after the operation there is no need to even bother with pain medication. Otherwise, don`t worry about an interaction :) ...Read more

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How is elevated bun related to pneumonia?

How is elevated bun related to pneumonia?

Elevated BUN: Elevated BUN represents a strained kidney most likely secondary to dehydration. Pneumonia is a significant illness that often leads to fever and dehydration. ...Read more

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What is the implication of elevated bun/creatin levels?

See details: Elevated levels of BUN and creatinine signify reduced kidney function. The higher the values, the more compromised the kidney function. ...Read more

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Low creatinine and elevated bun/creatinine ratioplease interpret?

Low creatinine and elevated bun/creatinine ratioplease interpret?

Stop worrying: Low creatinine is never a health concern. Reference ranges are set so that a few percent of healthies fall outside on either end. The ratio can be up if you're a little thirsty or ate a protein-rich meal lately. ...Read more

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Which pharmacokinetic process would be affected by elevated creatinine and bun levels?

Depends on drug: Many drugs are excreted by the kidneys and doses of those drugs need to be adjusted in people with elevated BUN/Cr. ...Read more

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What means an elevated BUN to creatinine ratio of 24 if both BUN and Creatinine are individually normal? BUN: 17.7, Creat: 0, 75. Take many fluids. Txs

What means an elevated BUN to creatinine ratio of 24 if both BUN and Creatinine are individually normal? BUN: 17.7, Creat: 0, 75. Take many fluids. Txs

Elevated ratio: Hi Oskcar. You lab levels are normal and your ratio is high due to your low creatinine level. If you had a high BUN-creatinine ratio that was abnormal due to dehydration, your serum sodium and chloride would be high. You did not mention those values in your test results. Were they elevated? If not, you need not worry, if they were, ingest more fluids to reduce them and lower your ratio. ...Read more

Toxicity (Definition)

Toxicity is the degree to which a drug or a substance can harm ...Read more