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Doctor insights on: Elevated Bun And Creatinine Levels

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Which pharmacokinetic process would be affected by elevated creatinine and bun levels?

Which pharmacokinetic process would be affected by elevated creatinine and bun levels?

Depends on drug: Many drugs are excreted by the kidneys and doses of those drugs need to be adjusted in people with elevated BUN/Cr. ...Read more

Dr. Madhu Kandarpa
2,169 doctors shared insights

Creatinine (Definition)

It is a byproduct of creatine phosphate which is present in muscles. Levels are increased ...Read more


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What results in an elevated bun level with a normal serum creatinine?

What results in an elevated bun level with a normal serum creatinine?

See below: An elevated BUN with normal creatinine occurs most commonly in dehydrated individuals and is not a sign of kidney damage.It may also occur in in certain other conditions like bleeding in the intestines, artificial nutrition intravenously of Amino Acids and use of steroids. ...Read more

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Which etiology results in an elevated bun level with a normal serum creatinine level?

Which etiology results in an elevated bun level with a normal serum creatinine level?

Multiple causes: BUN is a breakdown of ingested protein, but becomes elevated compared to creatine, in cases of increased catabolism (breakdown). Such things as a high protein diet, use of some steroids, some infections, or volume depletion may commonly raise BUN levels. In a hospital setting, tube feeding, tpn, GI bleeding, infections, decreased flow to the kidneys, and use of steroids are frequent contributors. ...Read more

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Low creatinine and elevated bun/creatinine ratioplease interpret?

Low creatinine and elevated bun/creatinine ratioplease interpret?

Stop worrying: Low creatinine is never a health concern. Reference ranges are set so that a few percent of healthies fall outside on either end. The ratio can be up if you're a little thirsty or ate a protein-rich meal lately. ...Read more

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I have a high bun/ creatinine level (28) and a low creatinine level (0.5) . Should I be concerned or do something?

BUN/Creat Ratio: I personally would not worry about it since the high ratio is due to a slightly elevated BUN. This might be due to a diet high in non-essential amino acids (nothing to truly be concerned about) or a mild lack of water intake. If you are still concerned, please see your primary doctor and go over all of that with her/him. ...Read more

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What does it mean if both bun & creatinine levels are good, but the ratio is high?

What does it mean if both bun & creatinine levels are good, but the ratio is high?

Actual values: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, if both creatinine and BUN are normal you do not need to worry about the ratio. ...Read more

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What does it mean if both bun & creatinine levels are good, but the ratio is high?

Need numbers: It would help to have the actual numbers. The doctor who ordered these tests would be in a better position to advise as s/he knows your health status. ...Read more

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What means an elevated BUN to creatinine ratio of 24 if both BUN and Creatinine are individually normal? BUN: 17.7, Creat: 0,75. Take many fluids.Txs

What means an elevated BUN to creatinine ratio of 24 if both BUN and Creatinine are individually normal? BUN: 17.7, Creat: 0,75. Take many fluids.Txs

Elevated ratio: Hi Oskcar. You lab levels are normal and your ratio is high due to your low creatinine level. If you had a high BUN-creatinine ratio that was abnormal due to dehydration, your serum sodium and chloride would be high. You did not mention those values in your test results. Were they elevated? If not, you need not worry, if they were, ingest more fluids to reduce them and lower your ratio. ...Read more

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How can I lower my creatinine and bun levels?

Only if due to : Dehydration. If the elevation is due to dehydration you may lower it by drinking water. However, in almost all instances elevated BUN and especially creatinine. Warrant seeing your doctor asap. ...Read more