Doctor insights on:
Elevated Bilirubin Liver Disease
This organ plays a major role in metabolism and has a number of functions in the body, including glycogen storage, decomposition of red blood cells, plasma protein synthesis, hormone production, and detoxification. It lies below the diaphragm in the abdominal-pelvic region of the abdomen. It produces bile, an alkaline compound which aids in digestion via the emulsification of ...Read more
Total bilirubin 2.5 (Elevated), Direct bilirubin 0.5 (Elevated), Indirect bilirubin 2.0 (Elevated) All other liver enzymes normal. What causes this?
Rerun test: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, you need to re do the tests in non-fasting state. With the exception of elevated direct bilirubin, the findings are consistent with Gilbert syndrome, which is not a disease. See this site for more info: http://www.mayoclinic.org/diseases-conditions/gilberts-syndrome/basics/definition/con-20024904 ...Read more
Mirtazapine-elevated liver enzymes. Does drug induced elevated liver enzymes mean permanent liver damage?
Depends: Elevated liver enzymes can be due to a number of causes. Without knowing more information, it is difficult to answer. However, depending on the degree of elevation and the type of "liver enzymes" that are elevated, it can be due to fatty liver disease (very common now a days) or inflammation from other causes. Discuss with your pcp or a liver specialist what the next steps are. ...Read moreSee 2 more doctor answers
Kidney trouble: It is well known that diabetes can lead to significant complications in the organs where there are very small blood vessels, i.e. Your eyes, your kidneys, and your feet and hands. If you are not getting good blood sugars on your treatment regimen this will only get worse. I would wish for you a good relationship with your diabetes doctor and good treatment to control your blood sugars. ...Read more
Ttl. Bilirubin 4.5. Direct 0.9 and yellowing of eyes! liver functioning normal. Neg for hepatitis. Gallbladder ultrasound norm. Gilbert's disease?
Yes: Your description is classic for diagnosing gilbert's. Given how many repeated questions you have written questioning this diagnosis, you could spend $400 to get the gene responsible for gilbert's sequenced to verify the diagnosis. See: http://dnatesting.Uchicago.Edu/tests/65. ...Read more
Calprotectin 95, ALT & AST chronically fluctuating elevated,sigmoidoscopy normal,MRCP normal, could it be IBD causing elevated liver enzyme ?
IBD complication AIH: The calprotectin level (I'm assuming it's a stool test) is rather high 4 ur age (normal is less than 51 ug/g stool), which seems confirm IBD but unfortunately didn't spare u a sigmoidoscopy. Caveat: proton pump inhibitors like Prilosec falsely elevate calprotectin. Nonetheless, a common complication of IBD is autoimmune hepatitis (AIH) which can cause fluctuating liver enzymes & damage. TTY GI do ...Read more
AST elevated (65), ALT elevated (50) and total bilirubin elevated (3.0). All other enzymes are normal. Is this significant??
Bilirubin is the potentially toxic product of heme metabolism. It is formed by breakdown of heme present in hemoglobin, myoglobin, cytochromes, catalase, peroxidase and tryptophan pyrrolase. Eighty percent of the daily bilirubin production comes from hemoglobin. It requires conversion to a water-soluble form before elimination from the body by ...Read more
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