Doctor insights on:
Elevated Bilirubin Levels
Bilirubin is the potentially toxic product of heme metabolism. It is formed by breakdown of heme present in hemoglobin, myoglobin, cytochromes, catalase, peroxidase and tryptophan pyrrolase. Eighty percent of the daily bilirubin production comes from hemoglobin. It requires conversion to a water-soluble form before elimination from the body by ...Read more
Hemolysis: Very strenuous exercise that involves pavement-pounding can destroy enough red blood cells that the bilirubin and reticulocyte counts go up. As a pathologist, i'm always reminding folks to look at the person, not the numbers. If your bilirubin's up and it's not jogger's hemolysis or gilbert's, try to find the cause with your physician's help. ...Read moreSee 1 more doctor answer
Is it possible for elevated bilirubin levels and being vitamin d deficiency to have anything to do with each other?
Doubtful: I highly doubt any relationship between elevated bilirubin and vitamin D deficiency in adults. Given the epidemic of vitamin D deficiency, physicians would see thousands more patients with elevated bilirubin if there was a relationship between the two. That being said, a 2013 study from Asia suggests low vitamin D may be associated with elevated bilirubin in neonates. ...Read more
I have elevated CRP and C4 levels. C3 is normal. Last two blood work-ups also revealed slightly elevated bilirubin levels. What could this indicate?
Non-specific: Interpreting blood work can be a very tricky proposition. Each lab values needs to be interpreted within clinical context and in association with other blood tests. Elevated CRP can sometimes be normal, other times it is a marker of inflammation. Elevated bilirubin may also be normal but sometimes can be indicative of blood or gallbladder dysfunction. ...Read more
To the extent that: P vera would be associated with increased rbc turnover, a modest increase in bili is possible. However, the disease is one of proliferation more than destruction, so if the bili is quite high we need to evaluate. ...Read more
Can poor periphery circulation and capillary refill cause elevated bilirubin and liver enzyme levels?
Depends on the cause: Depends on the cause of elevated bilirubin.Bilirubin can be elevated due to many causes 1infectious hepatitis 2toxic hepatitis due to toxins and drugs 3gall stones and cholecystitis 4alcoholic hepatitis and cirrohsis 5liver cancer and metastatic cancer in liver 5gilberts syndrome so the prognosis and treatment depends on the cause of elevated bilirubin. ...Read more
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