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Doctor insights on: Elevated B12 And Folate Levels

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What would cause elevated B12 and folate (folic acid) levels?

What would cause elevated B12 and folate (folic acid) levels?

Stop worrying: We see these from time to time. They are no cause for concern. Reference ranges are set for the vast majority of people. Just be happy. Elevated B12 has some arcane significance in hematology but it does not apply to healthy people. Just be glad. ...Read more

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Folic Acid (Definition)

Folic acid, AKA folate (folic acid) (vit B9), is recommended for all women wanting to get pregnant -- 0.4mg (400mcg) daily, which is important for preventing birth defects like spina bifida. Women w/ a hx these disorders should take 10x that amt daily -- 4mg (4000mcg) through the 3rd month of pregnancy. It won't affect fertility, chances of conception/twins, or periods. ...Read more


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What causes high vitamin B12 levels?

Intake + Absorption: Vitamin b12, aka cyanocobalamin, is common in a huge variety of foods; low intake rare. However, none of us absorb B12 directly. Instead, the cells of the upper ? of the stomach which secrete hydrochloric, hcl, acid also produce & secrete a protein, called intrinsic-factor, which binds b12. The small intestines absorb intrinsic-factor with whatever B12 is bound, & the B12 is thereby also absorbed. ...Read more

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Are low iron levels and high bilirubin levels connected?

Are low iron levels and high bilirubin levels connected?

May be, may be not: Further evaluation is obviously needed. I can't say whether it is related or not without getting more information. In many cases- probably those two are not related. However in a case of colon cancer with metastatic disease to the liver- it can cause both increase of bilirubin level as well as low iron. Go to see your md and discuss further your condition. ...Read more

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What blood disorders/disorders can cause elevated B12 levels and low iron?

What blood disorders/disorders can cause elevated B12 levels and low iron?

Polycythema vera: Some times polycytemia vera can cause, but rare, this needs further work up, especially low. Iron that is most of the time due to bleeding. ...Read more

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What would cause a slightly elevated B12 and folate (folic acid) level on complete blood count?

What would cause a slightly elevated B12 and folate (folic acid) level on complete blood count?

Dietary supplents: The most likely cause of elevated B12 and folate (folic acid) is dietary or parenteral supplements. Other sources of B12 and folate (folic acid) are the diet itself. Consult your doctor for more information. ...Read more

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Low hemoglobin (11.6),low mch, high rdw, low alkaline phosphates, all other values normal including rbc and b12. Possible cause? Iron deficiency?

Low hemoglobin (11.6),low mch, high rdw, low alkaline phosphates, all other values normal including rbc and b12. Possible cause? Iron deficiency?

May be: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, iron deficiency is not uncommon in women in their reproductive years. It would be safe to take oral iron and multivitamin supplements and recheck hemoglobin at your next visit to your doctor. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex, if you have sex. ...Read more

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Previous ida. Now high B12 and folate (folic acid) levels. Ferritin result is not back. Significant hair loss and sob? Could high folate (folic acid) mask B12 deficiency? Thx

Previous ida. Now high B12 and folate (folic acid) levels. Ferritin result is not back. Significant hair loss and sob? Could high folate (folic acid) mask B12 deficiency? Thx

Masks anemia only: High folate (folic acid) can mask megaloblastic anemia caused by B12 deficiency but does not affect B12 levels. The high B12 levels you have are proof that you don't have B12 deficiency. I don't know what ida is. Hair loss ; sob can have many causes. It sounds like you are being evaluated for possible causes. ...Read more

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If hemoglobin and hematocrit levels are low, will platelet level also be low?

If hemoglobin and hematocrit levels are low, will platelet level also be low?

Not always: But if low hb, low hct are associated with low platelet , the it needs to be more evalauted as the conditions could be contributed by us such as alcohol use , or conditions of the bonemarrow from defective synthesis of precursor cells -called myelodysplastic syndrome, a bm failure blood has 2 types of cellular elements-red blood, white blood and platelets and their precursors come from bone marrow. ...Read more

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Are hemoglobin A1c levels related to glucose levels?

Are hemoglobin A1c levels related to glucose levels?

Diabetic measure.: The HgbA1C is a measure reflective of your degree of diabetic control in the long term. It essentially represents a three month average of your fingersticks, as if you took a fingerstick every minute, night and day, eating and fasting, for three months straight and then averaged them all. Technically, it's the percentage of red blood cells that have glucose attached to them. ...Read more

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High levels of copper and high levels of CPK enzyme?

High levels of copper and high levels of CPK enzyme?

See MD immediately: Copper levels in the body are very tightly controlled. Excess levels can occur when elimination is reduced, such as Wilson's disease, or when there is excessive intact (deliberate or by accident). This can lead to neurologic, blood cell, liver, kidney and muscle damage. Elevation of CPK is often a sign of muscle damage. You must see a MD immediately to determine cause and possible treatment. ...Read more

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Folic acid -24.6, serum B12 - 600, high folic acid may mask B12 def, what does that mean? is serum B12 falsly high? what other tests for B12 def?

Folic acid -24.6, serum B12 - 600, high folic acid may mask B12 def, what does that mean? is serum B12 falsly high? what other tests for B12 def?

See below: Folic acid does not affect blood test results for B12, i.e., it will not cause falsely high B12 results. High folic acid may mask hematologic effects of B12 but not all functions of B12. ...Read more

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What causes high vit b12?

What causes high vit b12?

Depends: Chronic myelogeneous leukemia, promyelocytic leukemia, polycythemia vera and also the hypereosinophilic syndrome can result in elevated levels of B12 mostly from increased production of haptocorrin. In addition, because the liver stores b12, liver diseases such as acute hepatitis, cirrhosis, hepatocellular carcinoma and metastatic liver disease can also cause a rise in serum b12. ...Read more

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Is high RBC folate (folic acid) associated with vitamin B12 deficiency?

Is high RBC folate (folic acid) associated with vitamin B12 deficiency?

Not likely: Please consult this site for info in this topic. Folate (folic acid) and B12 are needed for efficient red cell production and other functions, but lack of one does not increase the other. http://www.webmd.com/diet/folic-acid. ...Read more

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Are elevated B12 and folate (folic acid) levels bad? Cause of this? How to bring them down to normal levels?

Are elevated B12 and folate (folic acid) levels bad? Cause of this? How to bring them down to normal levels?

Needs evaluation: High B12 & folate (folic acid) is not dangerous per se (these vits. Have no known toxicity)& may not be serious, but high B12 may paradoxically be a sign of B12 deficiency & may also be caused by acute or chronic liver disease or leukemia, so deserves further evaluation-see http://healthyeating.Sfgate.Com/high-vitamin-b12-serum-levels-6037.Html high folate (folic acid) may be a sign of B12 deficiency or blind loop syndrome. ...Read more

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What happens if you have an abnormally high B12 level and high folate (folic acid) level?

What happens if you have an abnormally high B12 level and high folate (folic acid) level?

High B12 Folate (folic acid): I understand your concern. Researchers in Denmark have found that higher than normal levels of B12 may indicate a person is at risk of developing Lung, Colon and Liver cancer. National Institute Health Research stated-High folate (folic acid) does not appear to increase the risk of anemia among healthy people with low B12 levels See your physician for evaluation tests and treatment ...Read more

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Can liver problems cause low levels of vitamin D and vitamin b12?

Can liver problems cause low levels of vitamin D and vitamin b12?

Yes, but other: causes are more common. You may not taking enough of these vitamins with your diet. Try taking 5000 units of vitamin D3 daily for three months and retest. B12 is more complicated, if you have poor absorption you will need injection of B12. For now try taking about 50 micrograms of B12 daily by mouth and recheck in about 3 months. ...Read more

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Dexpression, lathergic, low level of vitamin b12. And vitamin d deficiency, low level of energy?

Dexpression, lathergic, low level of vitamin b12. And vitamin d deficiency, low level of energy?

And your question?: I'm not sure what you are asking. Yes, vit d deficiency can cause fatigue. It is easy to correct with 5-8000 iu of d3/day. B12 deficiency can be serious too- try 1000 mcg of sublingual b12/day ; if that does not help try injections. See http://bit.Ly/1fnt3ox ; http://bit.Ly/1607tg3 if fatigue persists after correcting then see a good doc to explore the many other possible causes of fatigue. ...Read more

Dr. Randy Baker
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Vitamin B12 (Definition)

Vitamin B12 is a vitamin which is a kind of nutritional agent ...Read more


Dr. Kristi Woods
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Folate (Definition)

Folate is a vitamin which is a kind of nutritional agent ...Read more