Doctor insights on:
Elevated Anticardiolipin Igm
Antiphospholipids: Autoimmune antibodies can be formed against natural (normal) cell surface proteins. When this happens, adverse effects can occur. Anti-cardiolipin antibodies have been associated with abnormal blood clotting events and recurrent spontaneous miscarrages. See a hematology specialist for advice on this problem. ...Read more
Do you rule out aps if anticardiolipin antibody and beta 2 glycoprotein (both IgG and igm) are often elevated but in borderline and weakly positive range?
See below: There are certain criteria that must be met in order for one to have aps. One of which is that one must have some type of thrombotic event. Antibodies alone do not make the diagnosis. Without knowing full details regarding your case, it is difficult to say whether you do or not. ...Read more
Anticardiolipin Ab: The primary consequence of the antiphospholipid antibody is non-inflammatory thromboembolic (clotting) disease. Virtually all venous and arterial systems have been cited, including large, medium, and small vessels. It could simply mean that the underlying disease process (lupus) is not being treated or controlled. ...Read more
Does anticardiolipin IgM (115ug/l) x 3 have any significance when it is rasied on its own? LA Positive but beta glycoprotein & other antibodies neg
Higher future risk: The cause of an elevated aCL without other diseases is unknown. That said, 50% of people with + lupus anticoagulant have or will have SLE. Presumably, manifestations require the aCL plus another problem - infection, one of a number of drugs, pregnancy, BC pills, etc. The significance is the higher than normal risk in the face of future immunological injury ...Read more
Positive ANA of 1:80 homogenous and Cardiolipin AB IGM of 17mlp. Labs drawn on accident. No symptoms. Should I be concerned? What could it be?
How do you feel?: Most people who have this discovered incidentally never have problems. ...Read more
My anticardiolipins IgM has come back high in the last two years ranging from 113 to 53 recently what does this mean? My ANA & Other antibodies Neg.
My anti-cardiolipin IgM was in nov 133 / 82 in jan & in feb it came down to 9.38. Should I still be referred & do I need it checked again if so when?
Ask first: Ask first why the test is being run. If there is a suspected blood clotting disorder, yes, you should see a specialist such as a hematologist. If there is an autoimmune disease process, you should see a rheumatologist. If neither of these apply, then question why the test is being run. ...Read more
My anti-cardiolipin IgM 133u/ml (nov), 82u/ml (feb). Who do I need to see with regards to this? What speciality.
My anti-cardiolipin IgM was checked to rule out mctd. It was in nov 133 / 82 in jan & in feb it came down to 9.38. Does it need to be tested again?
See details: Anticardiolipins never rule in or rule out mctd. They are used to diagnosis specific clotting disorders that can be associated with connective tissue disorders. The levels of anticardiolipins vary up and down and in your case they should be checked once or twice a year, not every month or two. I would urge taking an 81 mg asa daily as protection if your doctor agrees. ...Read more
My anti-cardiolipin IgM was in nov 133u/ml, 31st jan 82u/ml and on the 4th feb it came down to 9.38 mpl. Can it drop that much in 5 days? Is it error?
Anti-cardiolipin IgM was checked as part of tests for mctd. It was 133 nov / 82 in jan & in feb it was 9.38. Gp says there no needs to refer or treat?
? Referral: To have anti-phospholipid antibody syndrome you need to have 2 positive tests at least 3 months apart. Transient elevations are common and not risky. It's unusual that the first test was so high and it did not persist. If you still have other mctd symptoms you should see a rheumatologist. ...Read more
My anti-cardiolipin IgM was in nov 133u/ml, jan 82u/ml and on the feb it came down to 9.38 mpl. Pt 13.8 ptt 31.2 hypermobility of the joints. Normal?
Maybe: Having an anticardiolipid become positive is always concerning. I am glad it was repeated and came down. With that said an evaluation from a hematologist would be a good next step, as there are many other things to consider that go far beyond the scope of this forum. ...Read more
I have a swollen painful leg. I had a d-dimer 300, globulin 36 & neutrophil 6.44. Recent test anti-cardiolipin IgM was in 82u/ml pt 13.8 is it ok?
In nov my anti-cardiolipin IgM 133u/ml in feb it was 82u/ml. My ANA and celiac screen has come back negative but IgA 4.86g/l CRP 12.86, mchc 310g/l.
See details: Anticardiolipin antibodies tend to rise and fall but both values are significantly elevated. The igg fraction is more likely to be associated with clotting issues. ...Read more
Tested for anti cardiolipin IgM is negative (0.7) but IgG is positive (54.8) normal range of lupus anticoagulant, protein S and protein C activity help?
Not sure: I am not sure I understand the question. I suspect you are being evaluated for a blood clotting disorder and you have an elevated anticardiolipin IgG. One test however does not make the diagnosis of anti-phospholipid syndrome. ...Read more
OskarD071: This means that you have allergic tendencies but it doesn't tell you to what. ...Read more