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Doctor insights on: Elevated Alp

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Will elevated calcium cause elevated alp?

Will elevated calcium cause elevated alp?

Elevated alp?: Do you mean alkaline phosphatase? If you have an elevated bone specific alkaline phosphatase and elevated calcium, you likely have osteopenia and hyperparathyroidism. ...Read more

Dr. Andrew Seibert
666 Doctors shared insights

Alkaline Phosphatase (Definition)

The normal range is 20 to 140 iu/l.[12] high levels can indicate active bone formation occurring as alp is a byproduct of osteoblast activity (such as the case in paget's disease of bone). Levels are also elevated in people with untreated celiac ...Read more


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+ Antimitochondrial M2 antibodies w/ 4previous elevated ALP's. Most recent ALP normal. Still suggestive for PBC?

+ Antimitochondrial M2 antibodies w/ 4previous elevated ALP's. Most recent ALP normal. Still suggestive for PBC?

No: The diagnosis of PBC is made through liver biopsy. The other best tool is the biliruben. Taken together they give a diagnosis and prognosis for survival. As you know PBC is though to be an auto immune disease. ...Read more

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Cronic yellow acidic stool, occ RUQ pain, slightly elevated ALP. Previous gall US and Cck hida neg. Then BM explosive BROWN then norm brown finally after months of pain. Could a stone have cleared?

Cronic yellow acidic stool, occ RUQ pain, slightly elevated ALP. Previous gall US and Cck hida neg. Then BM explosive BROWN then norm brown finally after months of pain. Could a stone have cleared?

Gallstone unlikely: Gallstones don't usually cause changes in stooling. Mild all phos elevations are common and nonspecific. You more likely have a bowel issue. I would shift focus away from gallbladder and talk to your doctor about other possible causes of your symptoms. ...Read more

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What types of things can cause elevated ALT and ALP at the same time?

What types of things can cause elevated ALT and ALP at the same time?

Lots of things: Everything in the hepatitis family (the viral ones, medication, Wilson's, antitrypsin deficiency, non-alcoholic steatohepatitis) can do this by damaging both liver cells and bile drainage. Around 5% of older adults have high alk phos from subclinical Paget's of bone, so you need to look at all causes of elevated ALT. ...Read more

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My son (20) is 15mo post BMT for AML. He had aGvHD/liver. He has portal hypertension. ALP elevated for last 3 mo, up to 160. AST/ALT controlled. Norm?

My son (20) is 15mo post BMT for AML. He had aGvHD/liver. He has portal hypertension. ALP elevated for last 3 mo, up to 160. AST/ALT controlled. Norm?

Leukemia?: Does AML mean myelogenous leukemia? If so, the alk phos can stay up for many months. Remember, ALP is both a liver and bone enzyme-it can be elevated also during growth and bone marrow recovery. ...Read more

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Why would 16 yr old son have elevated AST 55, alp 199, bilirubin 3.7, low vit d, fatigue and irritable bowel symptoms. No tylenol (acetaminophen) use, also no mono.

Why would 16 yr old son have elevated AST 55, alp 199, bilirubin 3.7, low vit d, fatigue and irritable bowel symptoms. No tylenol (acetaminophen) use, also no mono.

More info is needed: Many viruses can cause mono-like symptom--cytomegalovirus, ebv, hiv--also many different types of hepatitis--a, b, c can certainly be associated with stated symptoms. Auto-immune hepatitis is also in the list. Careful hygiene and a careful examination are needed.
Feel better. ...Read more

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Hi, I am a 36 year old female status post 8 month delivery. My aLP is elevated to 276, AST 35, & ALT 62. What could be the causing the elevation?

Hi, I am a 36 year old female status post 8 month delivery. My aLP is elevated to 276, AST 35, & ALT 62. What could be the causing the elevation?

Several causes: There are several causes of elevated liver enzymes. Your doctor will need to check blood tests for lipids and hepatitis and then may need do a liver ultrasound to determine the cause. Common causes are alcohol, fatty liver and viral hepatitis. ...Read more

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Sternum and tailbone pain and elevated AST and ALT and an alp level of 129, what could it be?

Sternum and tailbone pain and elevated AST and ALT and an alp level of 129, what could it be?

Liver enymes: It is time for a full comprehensive medical exam with bloodwork and liver monitoring. I think your sternum and coccyx pain are not related; however must be examined too. Do not ignore these issues. ...Read more

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I have an eleveated ALP@246; GGT@161 and pending results for AMA. Hep Panel was negative. Normal RUQ U/S. What could cause this?

I have an eleveated ALP@246; GGT@161 and pending results for AMA. Hep Panel was negative. Normal RUQ U/S. What could cause this?

Alcohol/fatty liver: The two most common causes for elevated liver enzymes without viral hepatitis are alcoholic hepatitis and fatty liver disease. Cancer could also do it. You need a liver ultrasound to rule out a tumor. ...Read more

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My alp was. 25 is this bad? My bili is total 1.3 and direct 0.24 I have fatty liver bili kind of always is elevated mostly it's the total though

My alp was. 25 is this bad? My bili is total 1.3 and direct 0.24 I have fatty liver bili kind of always is elevated mostly it's the total though

No: The numbers you list don't seem high enough to be worrisome. Sometimes minor elevation of bili can be caused by fasting or a hereditary condition called Gilbert's syndrome. I can't tell if the alk phos is high without the normals for your lab. Fatty liver can be caused by overweight, alcohol use, or other causes. See your doctor to discuss the results, causes, and treatments. Good luck! ...Read more

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Though ALP is within normal range, it is elevating, with GGT, AST and ALT elevated to 69 U/L, 69U/L and 113 U/L. WHat could this mean?

Though ALP is within normal range, it is elevating, with GGT, AST and ALT elevated to 69 U/L, 69U/L and 113 U/L. WHat could this mean?

Need work up: Elevated liver enzymes should be repeated off alcohol and any meds that are not essential. If still up, you need to be tested for hepatitis B and C, hemochromatosis, Wilson's, and autoimmune hepatitis. Your liver might actually just be asking you for more exercise. Best wishes. ...Read more

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Dr did blood tests on 2 yo daughter. Her ALT (101), alp (355) and AST (60) were elevated. 2nd draw ldh also high (498) what other tests should we do?

Dr did blood tests on 2 yo daughter. Her ALT (101), alp (355) and AST (60) were elevated. 2nd draw ldh also high (498) what other tests should we do?

Who ordered them?: Why did she have the tests done? Did your doctor order them? Need more information...Hepatitis is one reason to have elevated liver function tests so a hepatitis panel might be helpful. Mononucleosis and CMV (cytomegalovirus) can also cause liver enzyme elevation so those might be helpful too. Then there are more esoteric tests that a specialist might want to order. Discuss with your physician 1st. ...Read more

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On ursodeoxycholic acid, transaminases chronically fluctuating elevated ALT 50-200 AST 40-80.ALP 90-107. MRCP normal, fibroscan normal, what could it be?

On ursodeoxycholic acid, transaminases chronically fluctuating elevated ALT 50-200 AST 40-80.ALP 90-107. MRCP normal, fibroscan normal, what could it be?

Difficult question: Why the ursodiol? If for blood cholesterol, there may be better options (I don't see CF or PBC on your history). Sounds like you're getting a work up for the elevated enzymes. Consider a virtual consult with GI specialist for a thorough review of lab and imaging results. ...Read more

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What causes a high vitamin d level along with high ast, ALT & alp? On pentasa, which can cause elevated ast/alt, but continues to rise & alp now hi.

Find cause: I'm not concerned about the vitamin d. Many people your age have high alk phos without any real problem. If stopping alcohol and unneeded rx's did not return ast/alt to a good level, time to rule out hepatitis b ; c, autoimmune hepatitis, hemochromatosis, wilson's (doubt at your age), autoimmune hepatitis (can be) ; consider if you may have metabolic syndrome / want to exercise more. ...Read more

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Alkaline phosphatase elevated should I be concerned?

Depends: This depends on how elevated the levels are and whether you have any associated conditions (for example, pregnancy) which are known to cause elevated levels. Talk to your doctor for more information. ...Read more

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What are the causes for elevated alkaline phosphatase?

Liver bone & GB: Liver disease, bone disease and gallbladder are most common. However an elevated alk phos does not absolutely mean there is a true disease present. ...Read more

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What does it mean when alkaline phosphatase, MCV, MCH & MCHC are elevated?

Mixed bag: ALP is a liver (or bone) enzyme; MCV; MCH and MCHC refer to size and color of red blood cells as in macrocytic (big red cell) anemia - given your conditions and meds, I would ask your doctor if you may have a B12 or Folic Acid deficiency ...Read more

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What could cause alkaline phosphatase levels to steadily increase over a period of years, now at an elevated level?

What could cause alkaline phosphatase levels to steadily increase over a period of years, now at an elevated level?

Alkaline phosphatase: Causes for elevated Alk phos: biliary obstruction stone, tumor, stricture; autoimmune biliary cirrhosis; liver infiltrates do to granuloma, fatty liver, amyloidosis, sarcoidosis, malignancy; meds like estrogen, chlorpromazine, erythromycin ; viral hepatitis; bone diseases: Paget's, osteomalacia, mets to bone, PTH disease, vitamin d def, fracture ...Read more

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Does elevated alkaline phosphatase cause bone pain?

No: Alkaline phosphatase is known as a "marker" of increased bone (or liver) metabolism. It is contained in bone (and liver) so it will be elevated when bone is being broken down or resorbed as in paget's disease or bone cancer. It doesn't cause bone pain per se, but whatever is causing the bone to break down in the first place (e.g. Paget's disease or bone cancer) is the cause of the pain. ...Read more

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What causes bone pain and elevated alkaline phosphatase in women?

Several conditions: You could have the condition called paget's disease, however they are some other diseases that could produce elevated alkaline phosphatase such as liver cirrhosis of obstruction of the biliary tract, some medications and some type of cancers. Proper testing is necessary for proper diagnosis. ...Read more