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Doctor insights on: Efudex Longterm Side Effects

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What side effects are associated with Adrucil (fluorouracil)?

Adrucil (fluorouracil): See: http://www. Drugs. Com/sfx/adrucil-side-effects. Html

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Dr. Isaac Francis
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Fluorouracil (Definition)

Fluorouracil is a topical cancer agent which is a ...Read more


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I'm treating a basal cell carcinoma on the side of forehead w/Efudex cream& since then it's been bleeding. Normal? When can I expect bleeding to stop?

I'm treating a basal cell carcinoma on the side of forehead w/Efudex cream& since then it's been bleeding. Normal? When can I expect bleeding to stop?

Need more info: It is not unusual for bleeding to occur maybe from trauma e.g. rubbing to hard on the lesion but may also portent sometime more serious. You must return to the physician who prescribed the Efudex and have him/her re-evaluate the lesion.

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What is the recovery time post efudex cream use on one's face? My husband has used it for 18 days, twice a day. His last application was this morning.

What is the recovery time post efudex cream use on one's face? My husband has used it for 18 days, twice a day. His last application was this morning.

1-2 weeks: Efudix should be use twice a day to the face for approx. 3 weeks or until scabbing occurs on the spots affected on the face. Once done with treatment, it usually takes 1-2 weeks to heal.
A product like Eucerin Aquaphor balm can be used to help speed up healing and helps the scabs fall off quicker.

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Does efudex (fluorouracil) cause cancer?

Does efudex (fluorouracil) cause cancer?

Not likely: Efudex (fluorouracil) is the brand name for topical (cream) 5-fu chemo. It is used to treat certain types of skin cancer. There is no evidence that topical 5-fu such as Efudex (fluorouracil) causes cancer.

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Can efudex (fluorouracil) cause more cancer?

Can efudex (fluorouracil) cause more cancer?

Unlikely: It is a topical agent used to treat pre cancer and superficial cancers that are not melanoma. Risk of any other type of cancer is next to none.

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What's the difference between efudex (fluorouracil) and carac creams?

What's the difference between efudex (fluorouracil) and carac creams?

Same: Both are commercial or trade names for the medication Fluorouracil it is also called adrucil, (fluorouracil) fluorplex. All are the same fomulation.

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What is the definition or description of: Efudex (fluorouracil) allergy?

What is the definition or description of: Efudex (fluorouracil) allergy?

Non existent: Efudex cream is an excellent agent for treating superficial malignant lesions of the skin. When applied q evening it results in a marked erythema around the skin, basal cell or squamous cell Ca. This is not an allergy but effector cells moving to the tumor site after Efudex has eliminated the cutaneous suppressor cells. After 10 applications A&D ointment used for an additional 10 applications

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How can I get rid of efudex (fluorouracil) scars?

How can I get rid of efudex (fluorouracil) scars?

No one answer.: Scars of any kind need to be carefully evaluated by a board certified plastic surgeon skilled in multiple techniques and treatment options for scar revision. Regardless of the original cause of the scar, a scar may be visible due to one or more of the following reasons: color, texture, or shadows created by mismatched edges. Treatment recommendations will depend on the nature of your scars.

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Will efudex (fluorouracil) have any affect at all on a melanoma or just basal?

Will efudex (fluorouracil) have any affect at all on a melanoma or just basal?

Minimal: You should not use effudex (5-fu chemo cream) on a melanoma lesion. The only curative treatment is surgical resection of skin melanoma in early stage. If you have advanced disease, you should talk wth your oncologist regarding treatment options such as interleukin-2, ipilimumab, vemurafenib or a clinical trial.

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I am starting to use efudex (fluorouracil) precancer cream. Is my whole face going to be a mess?

I am starting to use efudex (fluorouracil) precancer cream. Is my whole face going to be a mess?

Efudex (fluorouracil): Skin irritation, burning, redness, dryness, pain, swelling, tenderness, or changes in skin color may occur at the site of application. Eye irritation (e.g., stinging, watering), trouble sleeping, irritability, temporary hair loss, or abnormal taste in the mouth may also occur. Consult your doctor with any of these side effects.

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How can you tell if efudex (fluorouracil) has cured your skin cancer?

How can you tell if efudex (fluorouracil) has cured your skin cancer?

Biopsy: Efudex (fluorouracil) is a topical chemotherapy (5-fu). The only way to ascertain that Efudex (fluorouracil) (or any other treatment) has cured your skin cancer is by biopsy of the area to see if there is viable cancer cells remained.

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How effective is fluorouracil (Efudex) for treating basal cell cancer?

How effective is fluorouracil (Efudex) for treating basal cell cancer?

Very: The majority of small and even intermediate basal cell cancers can be cured by applying EFUDEX (fluorouracil). The resulting erythema is secondary to destruction of local suppressor cells in the tumor field and influx of effector cells to destroy the tumor. The EFUDEX (fluorouracil) is applied locally for 10 days followed by 10 days of A&D ointment May repeat if needed.

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Why do I still have an extremely itchy, red rash when I used efudex (fluorouracil) months ago?

Why do I still have an extremely itchy, red rash when I used efudex (fluorouracil) months ago?

? how used: Efudex (fluorouracil) or 5FU cream is applied to certain superficial skin malignancies. If eliminates suppressor cells and allows effector cells to enter and destroy tumor such as basal cell tumors. It should be used daily for 10 days followed by Vit A&D ointment for 10 days to eliminate red rash. Latter may be repeated.

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Just diagnosed with precancerous squamish cell cancer. On efudex (fluorouracil). What else should I do? I am male, balding, 64, live in ottawa, canada.

Just diagnosed with precancerous squamish cell cancer. On efudex (fluorouracil). What else should I do? I am male, balding, 64, live in ottawa, canada.

Easy to handle: Squamous precancers are called actinic keratoses and often (but not always) result from sun exposure. Efudex (fluorouracil) is hugely effective in changing their environment so they usually just go away without danger to you. They'll kill only if badly neglected. Here in the states, balding guys like to wear ball caps. Have somebody keep an eye on your head and other sun-exposed places as you'll likely get more.

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Efudex (fluorouracil) script for face and forehead, twice per day for two or three weeks. When do I know to stop applying? Can I use aquafor during application?

Efudex (fluorouracil) script for face and forehead, twice per day for two or three weeks. When do I know to stop applying? Can I use aquafor during application?

Try 3! Stop w/pain.: Efudex (fluorouracil) targets pre-cancerous skin lesions for destruction. It is common to experience redness, irritation and erosions with use, particularly at the pre-cancerous sites. Generally speaking, 3 weeks is the recommended course unless the pain from use is severe. Moisturizers are helpful but aquafor has lanolin which may cause an allergic reaction itself. Try vaseline if you experience this.

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I am 3 days post efudex (fluorouracil) treatment on forhead, temples and bridge of nose and have significant swelling, is this normal?

I am 3 days post efudex (fluorouracil) treatment on forhead, temples and bridge of nose and have significant swelling, is this normal?

Depends: Without an exam, I can only give general information, general swelling everwhere wouldn't be usual. Swelling/irritation at the area of treatment is pretty common but can require modification of treatment. Cannot say in your particular case, dermatologic conditions are hard to discuss without seeing them.

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Using Efudex 5% for Genital Warts (penis shaft) once every 10 days for 10wks. I put Efudex on then apply small piece of plastic over area w/ bandaid overnight. Bad or good idea? DR., what is your opinion on proper application & use of Efudex for HPV.

Using Efudex 5% for Genital Warts (penis shaft) once every 10 days for 10wks. I put Efudex on then apply small piece of plastic over area w/ bandaid overnight. Bad or good idea? DR., what is your opinion on proper application & use of Efudex for HPV.

Genital wart Rx: Efudex (fluorouracil) is not a normally recommended treatment for genital warts. It often would work, but other treatments often are preferred. Occlusive treatmetn will increase side effects. Whatever treatment is used, if it doesn't work after 3-4 weeks, another should be tried. See a doctor to reconfirm the diagnosis and advice different treatment. Several others are available. Good luck!

Dr. Marvin Ott
33 Doctors shared insights

Efudex (Definition)

Efudex is a topical cancer agent which is a ...Read more