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Doctor insights on: Effexor Vs Wellbutrin Side Effects

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I had intolerable side effects on effexor (venlafaxine). Now that I am taking a mood stabilizer, will I be able to tolerate wellbutrin?

I had intolerable side effects on effexor (venlafaxine). Now that I am taking a mood stabilizer, will I be able to tolerate wellbutrin?

Possibly: The two meds are different classes. Each person is different in how each med can affect. As long as your doctor has provided the prescription and you stay in contact/ open communication and feedback, it is worth a try. Good luck. ...Read more

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Dr. Alan Ali
781 doctors shared insights

Bupropion (Definition)

Also called wellbutrin (bupropion) or zyban or aplenzin, is an atypical antidepressant & smoking cessation aid, which has mild psychostimulant action. It is a norepinephrine/dopamine reuptake inhibitor. It can lower seizure threshold at high doses, ...Read more


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On Effexor (venlafaxine) XR 75mg, Can my doctor add Wellbutrin to help with depression and also the sexual side effects of Effexor (venlafaxine)? Dosage?

On Effexor (venlafaxine) XR 75mg, Can my doctor add Wellbutrin to help with depression and also the sexual side effects of Effexor (venlafaxine)? Dosage?

They can: but a plan is needed and pills don't fix all problems. Remember that ! See if you can find what your issues are and find a good talk therapist. ...Read more

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Why aren't I getting better on my antidepressant? i've taken bupropion olanzapine venlafaxine reboxetine. no better, just side effects.

Why aren't I getting better on my antidepressant? i've taken bupropion olanzapine venlafaxine reboxetine. no better, just side effects.

Hang in.: Each antidepressant requires a full dose for a length of time -- a few weeks. (it is common to give up on too low a dose.) Also, as you suggest, some people will need additional medicines. Then again, verify that you don't have a medical cause that needs treatment; and that you are not taking drugs that interfere. And consider psychotherapy. ...Read more

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Can you please compare/contrast Effexor (venlafaxine) XR vs. Wellbutrin xl?

Can you please compare/contrast Effexor (venlafaxine) XR vs. Wellbutrin xl?

Very different meds: Effexor (venlafaxine) xr works on serotonin and ne reuptake; wellbutrin xl works on ne and dopamine. Both are long-acting, and both work for depression. Effexor (venlafaxine) can help anxiety + depression; wellbutrin does nothing for anxiety. With wellbutrin the main dangerous side effect can be seizures; with Effexor (venlafaxine) it's possible hypertension. Sexual side effects with effexor; not so with wellbutrin. This isn't all! ...Read more

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Which would be less likely to result in discontinuation syndrome: Wellbutrin + an SSRI or Effexor (venlafaxine) XR?

Which would be less likely to result in discontinuation syndrome:  Wellbutrin + an SSRI or Effexor (venlafaxine) XR?

If you're asking : about potential withdrawal symptoms, you need to call your PCP first. Otherwise you may not be feeling well if you do this cold turkey. Any of the SSRIs or antidepressants have this issue, if you've been taking it chronically for a long time. If you just started, this may not be as big of a problem. So call your doctor first. ...Read more

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CAN I TAKE EFFEXOR (venlafaxine) 150MG WITH WELLBUTRIN OR LADOSE ?

Do not self medicate: It is not a good idea to take these two medications together without active supervision by a doctor. This is not a good issue for self medication. Please consult your doctor. ...Read more

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I'm changing my medication from Effexor (venlafaxine) 300mgs to wellbutrin 150mgs. How long before i notice a change in my mood?

I'm changing my medication from Effexor (venlafaxine) 300mgs to wellbutrin 150mgs. How long before i notice a change in my mood?

Many Variables: When switching from one antidepressant to another it is difficult to predict how quickly the new medication will take effect. Generally one expects an antidepressant to begin to work after two weeks with the maximum benefit at six weeks. One should taper slowly off Effexor (venlafaxine) due to discontinuation symptoms. These would include anxiety and flu-like aches and pains. Work closely with your md. ...Read more

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Can effexor/wellbutrin cause an increase in addiction or addictive symptoms?

Not that I know of: Effexor (venlafaxine) if taken for a period of five or six weeks and stopped suddenly can have significant withdrawal. Wellbutrin is used to help people who are addicted to cigarettes stop smoking but doesn't block withdrawal symptoms. That's as close to" addiction or addiction symptoms" as i can get regarding those two medications. ...Read more

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Can wellbutrin and effexor (venlafaxine) cause seizures?

Can wellbutrin and effexor (venlafaxine) cause seizures?

Wellbutrin, (bupropion) possible: Wellbutrin (bupropion) can cause seizures over a certain dosage. Your doctor is aware of this, so follow his/ her instructions and do not take more medication than prescribed. ...Read more

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How do you know if you need an snri or dnri? (seeking info on symptom determination) was on Effexor (venlafaxine) yrs ago, considering wellbutrin now.

Stop smoking: It is a little known fact that 65% of smokers get depression. I would recommend a trial on wellbutrin under your doctor's supervision. Fewer side effects than effexor, (venlafaxine) no withdrawal, and knocks out smoking cravings quite well. Why not kill two birds with one stone? ...Read more

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Does wellbutrin make you angry? Tried 10+ yrs ago - it did. Effexor (venlafaxine) worked well then but is too strong now. Need to try something (+ quit smoking)

Does wellbutrin make you angry? Tried 10+ yrs ago - it did. Effexor (venlafaxine) worked well then but is too strong now. Need to try something (+ quit smoking)

EXPLORE: Sounds like you may need meds and help regulating them. Bring issue to psychiatrist who will be most familiar with the meds you mention. ...Read more

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I take Zoloft a.M.Plus wellbutrin 150 in the morning and at night. I travel a lot and cannot always obtain wellbutrin. Friends have advised effexor (venlafaxine). ?

I take Zoloft a.M.Plus wellbutrin 150 in the morning and at night.  I travel a lot and cannot always obtain wellbutrin. Friends have advised effexor (venlafaxine). ?

Do not listen : To friends. Effexxor and wellbutrin work on different parts of the brain. You can not substitue one for the other. If you miss a dose of wellbutrin you will not have ill effects of withdrawal. If you missed medications on several days of either zoloft or Effexor (venlafaxine) you would. You should stick with the wellbutrin especially if it is working with you. There is a vacation override to get enough for trav. ...Read more

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Can lutera be the cause of severe fatigue/moodswings when combined with Effexor (venlafaxine) and wellbutrin?

Not likely : Birth control is not likely to cause that. Usually people are prescribed Effexor (venlafaxine) and wellbutrin for those exact symptoms. The underlying problem making you need those medications seems like a more likely cause. ...Read more

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I take Effexor (venlafaxine) and wellbutrin for panic disorder. What other treatments are best besides medications?

Talk therapy: Even with medication, i think it is a very goo idea to do some cbt talk therapy. That can help you feel more skilled (less helpless) in moderating or avoiding attacks. You may not need the meds if you are successful. Also meditation and certain exercise programs can be a good support for correcting this disorder. I'm impressed by your interest in self-management. I bet you'll do well. ...Read more

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I've been taking Effexor (venlafaxine) for almost two years i suddenly stop to use wellbutrin to quit smoking as well I'm very emotional and just not feeling mysel?

I've been taking Effexor (venlafaxine) for almost two years i suddenly stop to use wellbutrin to quit smoking as well I'm very emotional and just not feeling  mysel?

Stopping smoking: Even with the help of Wellbutrin, stopping smoking can be difficult in terms of feeling emotional and irritable. Put that together with a sudden discontinuation of Effexor (venlafaxine) and you have double the emotional stress. Antidepressants, especially Effexor (venlafaxine), should not be stopped suddenly. Speak with your doctor about weaning off while starting Wellbutrin. ...Read more

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Can wellbutrin and effexor (venlafaxine) go together to help GAD, OCD, and depression?

Can wellbutrin and effexor (venlafaxine) go together to help GAD, OCD, and depression?

Sure: This is a fairly standard cocktail for depressive and anxiety disorders. While I prefer the newer version called Pristiq (desvenlafaxine) (because you don't need to titrate the dose like Effexor XR) ... That's more a matter of physician preference, hope that helps! ...Read more

Dr. Krishna Kumar
537 doctors shared insights

Venlafaxine (Definition)

It belong to classification of snri antidepressant also help anxiety start slow go slow its approved for depression and anxiety disorder there are some common side effects important never stop suddenly always taper slowly if you ever ...Read more


Effexor (Definition)

Venlafaxine is a non-tricyclic which is a kind of serotonin-norepinephrine reuptake inhibiting drug (atypical anti-psychotic ...Read more