Doctor insights on:
Effectiveness Megace Endometrial Cancer
Yes: Hormonal therapy (including megace (megestrol), (megestrol) tamoxifen) can be used in the treatment of certain endometrial cancers which have recurred or spread to other sites. Patients with tumors positive for the Progesterone receptor especially may respond to megace (megestrol). ...Read moreSee 2 more doctor answers
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Why would an endometrial ablation and megace (megestrol) be better than hysterectomy in someone with endometrial cancer?
Yes: Typically, endometrial cancer develops through a series of precancer stages. And, typically these early stages are signaled by abnormal bleeding. If you are over the age of 35, see your doctor, and have a biopsy of the lining of the uterus...This is the best way of of finding precancer before it turns into cancer. ...Read moreSee 2 more doctor answers
Many factors: The risk of endometrial cancer is increased by obesity, diabetes, and persistently high estrogen levels, such as may occur with a condition like polycystic ovaries. Genetics also plays a role, especially with lynch syndrome which increases colon, endometrial, and ovarian cancers. Use of oral contraceptives or the Mirena (levonorgestrel) iud can decrease the risk of endometrial cancer. ...Read moreSee 3 more doctor answers
Several: Common endometrial carcinoma has been related to unopposed estrogen, as in obesity, the presence of an estrogen-producing ovarian or other tumor, also to early menarche, never having been a mother, older age, and a hereditary mutation (hnpcc) that also produces colon cancers without polyps. Even if you are not at extra risk, any abnormal bleeding needs a physician's attention. ...Read more