Doctor insights on:
Eeg In Cjd
In creutzfeldt jacob disease (cjd) and/or new variant cjd, is the classical/alternate complement pathway negatively affected in any way?
No: There's no inflammatory response to the prions. Given that everything affects everything else in a petri dish (which is why everything supposedly causes and prevents cancer), i must advise you that this line of inquiry isn't going to lead to anything helpful. I'm glad you have an inquiring mind, thanks for asking. ...Read more
Seizures: There is no difference in the appearance of these seizures. Most are all Tonic/clonic type seizures. THe cause and treatments of the two types differs. Hope this helps ...Read more
When cjd is such a rare disease, why would a doctor declare a cjd diagnosis without a biopsy? Father had seizures, false positive prion test, dementia
What is a diagnosis: There is a difference between a confirmed diagnosis and a clinical diagnosis. Sometimes a clinical diagnosis is made, without confirmation. For many illnesses, there is no confirmatory test. Most people determine CJD with spinal fluid testing, a biopsy, or autopsy. ...Read moreSee 2 more doctor answers
Hypnagogic hallucination related to epilepsy? Had regular micro- or macropsia, other visual distortions before sleep, ended up diagnosis with t.L.E at 20.
Other consdierations: Micropsia and macropsia can be a symptom of epilepsy or of migraine. Symptoms of seizures are usually stereotyped, if there are a variety of visual distortions less likely to be epilepsy. Speak to your neurologist. Consider a 24 hour ambulatory eeg that might capture the symptoms on the recording to make a specific diagnosis. ...Read more
Possibly, not surely: One small study has shown that bipolar patients -- even when not in a mood episode -- have decreased Alpha activity in their eeg's. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3253163/ they were also free of medications for at least 2 weeks for the study. The authors feel this may differentiate bipolar from schizophrenia eeg's. It doesn't seem diagnostically definitive on its own, though. ...Read moreSee 1 more doctor answer
Got13small inactive demyelinations in the brain.Neurologists said not ms-demyelinations disposed different.Is pet scan enough to confirm or infirm ms?
My son has cerebral palsy, autism, catatonic schizophrenia, seizures, mental retardation, lower left lobe of brain is missing, strabismus and was born?
Could be: One small [18 patient] study has shown that bipolar patients -- even when not in a mood episode -- have decreased Alpha activity in their eeg's. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3253163/ they were also free of medications for at least 2 weeks for the study. The authors feel it may differentiate bipolar from schizophrenia eeg's, but it's not diagnostically definitive on its own. ...Read moreSee 1 more doctor answer
Had polysomnography. Please explain: increase in phasic motor activity w/o stereotypical behaviors seen during REM sleep. ?
Which brain tests are done in awake part of awake brain surgery? Speech test, tests of extremities movement , memory tests or which?
Depends : On what part of the brain is being operated on. Mostly speech and movement testing. Squeezing object. Counting, repeating phrases. Things like that. ...Read more
My child has:decreased REM sleep & frequent wakings, migrational abnormality in brain that causes seizures, & behavioral probs.Is all of this connected?
Yes, an underlying: Neurological impairment likely causes all symptoms. Seek evaluation by a developmental/behavioral pediatrician to search for a genetic or other medical cause. There are known syndromes with lack of rem sleep, the most common of which is down syndrome. Comparative genomic hybridization & a dna probe for fragile x are genetic tests used when there are no physical findings of a specific syndrome. ...Read moreSee 1 more doctor answer
History 35 F. Headache,lft eye floaters
MRI findings:Multiple 20white matter lessons in the supratentorial brain, likely demyelinatingdisease. Worried?
2 tonic-clonics in under a year (normal EEG and MRI), depression, tremors in left hand, sleep apnea, mouth ulcers, freq. infection. What's wrong?
More info needed: Thanks for your question. I understand that this can be very scary, especially when you don't have a clear cut diagnosis. I would recommend getting a second opinion, preferably from a large academic center. Definitely something going on and we need to get some answers for you. ...Read more
Fleisher et al (Neurology, 2011) found Depakote accelerated brain atrophy in Alzheimer's. Should those with family history of Alz. avoid Depakote?
My mother's brain MRI shows hyperintense focus in t2w1/flair images in cerebellar vermis.Impression: ischemic focus in the cerebellar vermis.Explain.
Look at entire study: T2 and flair signal can be evidence of an "ischemic focus, " otherwise a stroke. However, other things could be in the mix, such as a tumor or demyelinating process. The radiologist will have looked at the other sequences. Sometimes, however, it can be tough to tell. ...Read more