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Doctor insights on: Eds In Elderly

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What's transmission of eds?

What's transmission of eds?

Genetic: The only common form of eds is type iii. This is because afflicted individuals rarely reach childhood; and, certainly not adulthood. Eds iii is an autosomally dominant gene which means that 50% of children of the affected person will have the disease; or each child has a 50% risk of developing the disease. ...Read more

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What is inheritance and pentrance of eds?

What is inheritance and pentrance of eds?

Depends: Ehlers danlos is a family of disorders, which has 6 major and several minor types. Given the multiple genes involved, it can be inherited in both autosomal dominant and autosomal recessive patterns, and can even spring from a de novo mutation. Penetrance depends on the type of mutation, and can therefore not be reliably calculated without more information. ...Read more

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Difference between eds and marfans?

Difference between eds and marfans?

Complications: There are several forms of both. Ehlers-danlos syndrome is often associated with skin hypersensitivity and aortic dissection, dependent on type. Marfans is more associated with joint hyperextensibility, cataracts and sometime aortic dissection. ...Read more

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My husband has eds hypermobility can he get disabled?

My husband has eds hypermobility can he get disabled?

Not necessarily: Good teaching in joint protection will prevent disability. Fibromyalgia frequently accompanies people with hypermobility without apparent arthritis. I encourage your husband to take care of himself so that he does not become disabled. Living off of disability is a meager existence. ...Read more

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Are there any problem with hearing that occurs with eds?

Ehlers-Danlos?: I am assuming by "eds" you mean ehlers–danlos syndrome. If so, then no. There are no hearing problems that are associated with eds. Poor balance (which s an inner ear problem) is common. ...Read more

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Is it possible for people with eds type 4 (vascular) to live normal lives?

Is it possible for people with eds type 4 (vascular) to live normal lives?

Very difficult: True Ehler-Danlos type 4 is characterized by facial changes, translucent skin through which vessels can be seen, easy bruising, and uterine and cardiac problems related to medium and large artery damage. Each event is treatable to some degree, pregnancy is advised against, and some problems require emergency treatment. It is autosomal dominant. With good care one may live long but not normally. ...Read more

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Are there any base-line protocols for testing that are recommended for all types of eds?

Are there any base-line protocols for testing that are recommended for all types of eds?

Yes.: Both clinical exam and genetic testing needed. A good pediatrician or geneticist are most likely to diagnose this, since presentation is early. I personally would see a geneticist if this diagnosis is in question. The hypermobility of joints leads to accelerated arthritis, ie. Osteoarthritis, and sprains. ...Read more

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Why do some with clinical eds diagnoses test negative for veds, but have vascular events?

Why do some with clinical eds diagnoses test negative for veds, but have vascular events?

Older testing: If a comprehensive evaluation is done the people with vascular risk can be determined. The incidence of vascular complications reflects available testing about 15 years ago. With improved testing techniques unanticipated vascular complications are rare without additional risk factors to include smoking. ...Read more

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Can any doctors or people who've been treated for eds please tell me how to get diagnosis?

Can any doctors or people who've been treated for eds please tell me how to get diagnosis?

Clinical criteria: It is usually a clinical diagnosis made using a set of clinical criteria; however, there are some genetic tests that can look for some variants of eds. ...Read more

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Do 10-25% of those with classical eds who tested negative for vascular eds have vascular issues?

Do 10-25% of those with classical eds who tested negative for vascular eds have vascular issues?

Depends: Would not focus so much on percentages, but instead would present your symptoms to your rheumatologist. Would try to seek out eds centers who understand the condition more than most and have seen a larger volume of eds patients (usually at university hospitals). ...Read more

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I've found it impossible to find a dr. That is knowledgeable enough about eds III to help me properly manage it. How can find a dr. That is able to?

Difficult: In reality, there are very few doctors that deal with ehlers danlos. Geneticists are usually the experts in diagnosing this but there is no true treatment. Non-narcotic pain rx and physical therapy to try to strengthen joints are used. Other than that, learning coping skills to live with this bothersome but non-fatal condition is key. Good luck. ...Read more

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How do you get eds?

How do you get eds?

Genetic!: You are born with it. It (several variants) are genetically acquired and in the patient's dna. It not acquired! Treatments are symptomatic. There are no cures. ...Read more

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What are the types of eds?

What are the types of eds?

EDS types: There are 6 major types of eds, they are inherited disorders marked by loose joints, hyper elastic skin that bruises easily, easily enlarged blood vessels. They are called types 1 through 6. A variety of genetic mutations cause problems with collagen, the material that provides strength to soft tissue structures and bone. Collagen typing and gene mutation testing can determine the eds type. ...Read more

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What are the signs of eds?

What are the signs of eds?

Loose-jointedness: There are several variations of eds but they all have loose-jointedness as a primary symptoms. Increased elasticity of the skin may also be present. ...Read more

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What are the manifestations associated with eds?

What are the manifestations associated with eds?

EDS: Excessive daytime sleepiness is exactly that. People typically will be tired during the day, fall asleep easily during activities that they should not falls asleep and may have a hard time staying awake while driving.
It is also the diagnosis we typically use for patients so that they can qualify for a sleep study when we have concerns about sleep apnea. Sleep studies can be $2-4k tests. ...Read more

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Are there any adults with eds who don't know it?

Are there any adults with eds who don't know it?

Yes: Generally, these are wonderful gymnasts, ballerinas and people who easily dislocate their joints to perform some pretty amazing feats, such as escaping from a strait jacket. However, the price is very high for those who use their flexibilty. They have to retire early from the severe form of premature osteoarthritis that they develop. ...Read more

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Does age increase the severity of eds symptoms/problems?

Does age increase the severity of eds symptoms/problems?

Yes: Ed becomes more common with increasing age. However, other factors play a role and are certainly more controllable. Not smoking, and controlling blood sugars and blood pressure will help symptoms of ed. Also, exercising will increase blood flow and decrease symptoms of ed. ...Read more

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How long can someone with eds live after symptoms begin?

How long can someone with eds live after symptoms begin?

It depends: There are several subsets of eds as well as a condition known as benign hyper mobility syndrome. Most individuals with eds have relatively mild disease and can expect a normal life span. ...Read more

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Why did our geneticist say it was not so bad to have eds?

Why did our geneticist say it was not so bad to have eds?

Tends to be "mild": Most cases and types of eds have fragile skin and joint dislocation as the worst consequenses. However the vascular type can be devestating with spontaneously rupturing blood vessels in multiple organs causing bleeding or bowel rupture. Eds can be confirmed by genetic testing and typed by skin biopsy. ...Read more

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I just got diagnosed with eds and wonder if my kids have it?

I just got diagnosed with eds and wonder if my kids have it?

Heck with gentic: Consular, because we have many type of this diseae.
Ehlers-danlos syndromes are a genetically, biochemically, and clinically diverse group of heritable connective tissue disorders. ...Read more

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Can you explain why there are crossovers (overlaps) among the different types of eds?

Can you explain why there are crossovers (overlaps) among the different types of eds?

Complicated: There are a number of types of eds and they are slightly diiferent diseases based on their individual genetic abnormalities. ...Read more

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Can you explain why there are "crossovers" of characteristics among the different types of eds?

Collagen: Eds has many different types. In most of its forms, the defect involves some aspect of collagen. Collagen is one of the basic building blocks of connective tissue which is found in all organs, joints and blood vessels. Depending on the exact type of genetic defect, and becasue collagen is found everywhere, there is cross-over in the types of eds with similar manifestations. ...Read more

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I am pretty sure that I have EDS are there any tests or things I should do to go about getting a diagnosis?

I am pretty sure that I have EDS are there any tests or things I should do to go about getting a diagnosis?

Consult geneticist: Ehlers-Danlos Syndrome is a genetic disorder with hyper elastic connective tissue and can be inherited recessive or dominant. A thorough exam and history and gene analysis or skin biopsy can confirm diagnosis, as there are 13 different types, and other conditions like Marfan's have similar symptoms. See https://ehlers-danlos. Com/what-is-eds/ for detailed information. ...Read more

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What is ehlers-danlos syndrome (eds)?

"Ehlers–Danlos": Ehlers–danlos syndrome (also known as "cutis hyperelastica") is an inherited tissue disorder caused by a defect in the body's synthesis of collagen. Collagen in connective tissue helps tissues to resist deformation. In the skin, muscles, ligaments, blood vessels and organs, collagen plays a very significant role and with increased elasticity or "stretchiness" they may not work right. ...Read more

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Do people with eds have more hernias?

Yes: I presume you mean ehlers-danlos syndrome, and yes, patients with this connective tissue disorder are more probe to hernia formation. ...Read more

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Can I have eds and lupus at the same time?

Yes.: EDS has 11 types, all hereditary, all with gene mutations causing problems with collagen in skin, bone, blood vessels. Symptoms include stretchy easily bruised skin, double jointedness, back pain, flat feet, early arthritis, etc.
Lupus, an autoimmune disease, requires 4 of 11criteria. MalarorDiscoidrash, Photosensitivity, OralUlcers, Arthritis, Serositis, KidneyDz, Neurologic Sx's, Blood abn, immunologic, ANA. ...Read more

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What does injection treatment for eds involve?

Mitochondrialsupport: Many enzymatic cofactors necessary for mitochondrial energy production, as well as antioxidants to clear up the free radicals which are produced by the working mitochondria which would otherwise injure them. Cofactors commonly injected include L-carntine (Carnitor)_ and vitamin B12, and a mix inositol, choline, and folate (folic acid). ...Read more

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Do gastrointestinal issues/problems occur with eds?

Not common: It depends on the subtype of ehlors-danlos syndrome, but not a common feature except in the most severe subtypes with excessive tissue tears without much trauma. Speak with york physician to see if you have any of those subtypes. ...Read more

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What's the difference between Marfan syndrome and eds?

What's the difference between Marfan syndrome and eds?

Stature and heart: Marfans people are tall, skinny, with valve problems, joint instability, but also have aortic problems. Ehlers danlos has hypermobility, subluxations, but also certain types of eds have tissue fragility, spontaneous pneumothorax, joint subluxation, and has difficulty healing. ...Read more

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Is there a way that heredity affects body weight like eds?

Is there a way that heredity affects body weight like eds?

Yes: Pima indians of the desert southwestern us live where food is scarce. Therefore, a gene that makes food storage into fat very efficient so that they survive the desert. Taken out of the desert, and fed a standard american diet, they will gain weight. Similar genes are certainly present that will soon be described once the human genome is fully known. ...Read more

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Do poor healing wounds often have connection to marphan or eds?

Do poor healing wounds often have connection to marphan or eds?

Yes: These disorders as well as several others can be evaluated by overall clinical picture and genetic testing. ...Read more

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What types of eds are associated with pain and/or chronic pain?

What types of eds are associated with pain and/or chronic pain?

? Ehlers-Danlos Syn.: The most common pain associated with eds comes from the fact that the connective tissue supporting the joints becomes lax and allows chronic joint dislocations. These people frequently notice they are "double-jointed" but later experience the chronic dislocations. A more serious kind involves blood vessels where they can spontaneously rupture. Eds can also be a limited to the skin. ...Read more

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What is the average life span of someone who has eds or marfans?

What is the average life span of someone who has eds or marfans?

Generally, normal: People with eds generally have a normal lifespan. Though, those with the rare vascular type of eds have a high risk of sudden death from organ or vessel rupture.

Heart-related complications can shorten the lifespan of people with Marfan syndrome, though many live into their 60's and 70's (i.e. Normal lifespan) with careful medical management. ...Read more

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What would be the initial and average cost of injection therapy if eds?

$120: A small amount of a chemical is injected directly into the corpora cavernosa. These chemicals are smooth muscle relaxants and thus help increase blood flow into the penis. ...Read more

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Is hypermobility syndrome different from the EDS hypermobility type? Is so, how?

Hyper mobility: Yes there is a large difference as hyper mobile joints is just about flexibility where EDS is a genetic problem of connective tissue so involves several organs. ...Read more

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How come many patients with clinical eds diagnoses do not test positive yet have vascular issues?

How come many patients with clinical eds diagnoses do not test positive yet have vascular issues?

No simple test: Eds in one form (vascular eds) can cause weakness of the blood vessels. If the vessel ruptures seriousl consequences can occur. Eds causes a weakness or loss of elasticity which can lead to stretching, ballooning out and eventual rupture. Probably easiest way to diagnose is with ultrasound or ct with contrast. ...Read more

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