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Doctor insights on: Eds Clinical Trials

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How can you sign up for a clinical trial if you have cancer?

How can you sign up for a clinical trial if you have cancer?

Ask oncologist: Trials have specific criteria to enroll payients. Usually your oncologist can help you figure that out. ...Read more

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Dr. William Singer
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Clinical Trial (Definition)

Science is a method using simplicity, theories and then tests to see if the theory works; always. Clinical trials involve comparing one approach/choice/treatment option with another & checking outcomes. Key methodology is double blind & ideally cross-over design with outcome measures to be used determined in advance. Double blind: neither participants or people near them know ...Read more


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Would a clinical trial test for health before starting drug?

Would a clinical trial test for health before starting drug?

Yes: It is typical for anyone who enters a clinical trial for a new medication to have a full exam and disclosure of complete medical information. It is routine to screen for certain type of patients who qualifies for the trial. ...Read more

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What is the average failure rate for a cancer clinical trial?

What is the average failure rate for a cancer clinical trial?

Hard to answer: There are so many clinical trials conducted in so many locations which make this nearly impossible to answer. Also, there are varying definitions of failure. For example, has a drug failed when it leaves 15% of cancer behind, even if the next best alternative typically leaves 20% behind? What if it kills 100% of the cancer, but then regrows in 2 months? So you understand the difficulties... ...Read more

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What treatment is best for terminal ca or should we try for clinical trial?

It depends: The main goal for treatment of terminal cancer is usually comfort care, to decrease the symptoms associated with disease, so the patient can focus on spending more time with family and friends. There are different phases of clinical trial. One should weigh the risk and benefit before participating it, specially the early phase trial when the toxicity and efficacy of a new therapy is unknown. ...Read more

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Anyone knows what is the cost of entering clinical trial for capsule endoscopy?

Anyone knows what is the cost of entering clinical trial for capsule endoscopy?

O: Most clinical trials provide all testing and treatments at no cost to the participants. Thanks for helping science progress. ...Read more

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Was anyone offered a clinical trial and turned it down and took the standard treatment instead?

Was anyone offered a clinical trial and turned it down and took the standard treatment instead?

Hard to say: A proper clinical trial is a randomized, blinded study. If a patient is enrolled in a clinical trial of a medication or therapy, then he/she and possibly the doctor should not know which therapy they are receiving - the new one being tested or the standard one (control or placebo). Otherwise, there would be a bias introduced that would invalidate the results. ...Read more

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18day clinical trial: potassion cloride, 750mg to 1500mg x 3 daily and 2 days of 6000mg is that too much? Effect on kidneys?

18day clinical trial: potassion cloride, 750mg to 1500mg x 3 daily and 2 days of 6000mg 
is that too much? Effect on kidneys?

Reassurance.: 6000mg kcl (about 80 meq) is not an excessive daily amount for an individual with normal kidney function. Just to put things into perspective, an average baked potato has nearly 1000mg of elemental potassium. Potassium doesn't really have a direct effect on the kidney function per se, but kidney dysfunction can have an effect on eliminating excess potassium from the body. ...Read more

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Would a clinical trial be appropriate for me?

Yes/It depends: Everyone is a potential candidate for clinical trials. Historically inclusion/exclusion (i/e) criteria have selected only the healthiest people. Increasing attention is being made to patients -- elderly, co-morbidities, pregnant, underserved, etc. One resource is clinicaltrials.Gov as well as web sites of major centers -- eg mayo clinic, cleveland clinic, etc. ...Read more

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Is it safe to participate in a clinical trial?

Is it safe to participate in a clinical trial?

Not entirely: The purpose of a clinical trial is to see if a new medication or treatment is safe & effective. Many times the answer is that the new treatment does not help. All medicines have side effects, sometimes quite serious, so trying a new medicine can be very risky- they may learn of a serious side effect from your experience! discuss the potential risks vs. Potential benefits with those conducting it. ...Read more

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Why should I participation in an MS clinical trial?

Why should I participation in an MS clinical trial?

Help others: Advancing our understanding of MS requires the dedication of researchers and also of patients. Clinical trials are the best tools to validate with reproducible evidence that a drug or intervention really has a benefit. Word of mouth or anecdotal evidence often fail to pass these hurdles and amount to pseudoscientific claims, lacking transparency to risk. ...Read more

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Dr. Lois Freisleben-Cook
344 doctors shared insights

Ehlers Danlos Syndrome (Definition)

Ehlers-Danlos Syndrome is a medical condition characterized by hypermobile joints, very elastic or stretchy skin that bruises easily, and other abnormalities. It is caused by defects in collagen, an important structural protein that is responsible for the strength of many different types of tissue including skin, ...Read more