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Doctor insights on: Eds Bones

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Do brittle bones from osteogenesis imperfecta hurt?

Do brittle bones from osteogenesis imperfecta hurt?

The broken ones hurt: Osteogenesis imperfecta patients have weakened, brittle bones. The bones break easily and broken bones are painful. A patient appearing in pain should be checked for a new fracture. A person with o.I. Without fractures, probably does not have bone pain, unless he has some areas of small-scale bone damage from over-movement, stress, or pressure. O.I. Specialists can better evaluate such a patient. ...Read more

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Bone (Definition)

Bone is a living growing tissue made mostly of collagen (protein that provides soft framework) & the mineral calcium phosphate that adds strength & hardens the framework. Two types of bone are found in the body; cortical (dense compact outer layer) & trabecular (makes up inner layer, ...Read more


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Hypermobile, poor healing, broken bones from cycle accidents. Need tests for brittle bone disease?

Hypermobile, poor healing, broken bones from cycle accidents. Need tests for brittle bone disease?

Collagen issue: Sounds more like a collagen issue. Unfortunately there not a treatment for poor collagen like there is for osteo-porosis. Still worth getting bone density, electrolytes, and hormones checked. (thyroid, para thyroid). ...Read more

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Osteopenia, osteoporosis or brittle bone disease--differences?

Osteopenia, osteoporosis or brittle bone disease--differences?

Genetic or not: Brittle bone disease is an inherited disorder of bone that is called osteogenesis imperfecta. Osteopenia and osteoporosis are disease of the bone where there is decrease density of the bone. This is associated with age, hormonal change, medications, smoking and other issues. Basically the bone cells are out of balance and take away more bone than they replace. ...Read more

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Could osteogenesis imperfecta affect the collagen within fibrous joints?

Could osteogenesis imperfecta affect the collagen within fibrous joints?

Osteogenenisis imper: OI affects or has to do with the collagen all over the body. Either too little or a variation in the structure of the collagen . These conditions are due to genes not coding for the correct or sufficient protein structure of the collagen. There are last count about 8 different subtypes of OI. So yes the collagen with in a fibrous joint can be affected as is the collagen in the body everywhere. ...Read more

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What causes brittle bones and hyperflexibility?

What causes brittle bones and hyperflexibility?

Two different things: Brittle bone disease is more commonly known as osteogenesis imperfecta (oi). It is a rare, usually inherited disorder that causes bones to break easily due to the body’s low production of collagen.Hypermobility describes joints that stretch farther than is normal. For example, some hypermobile people can bend their thumbs backwards to their wrists, bend their knee joints backwards. ...Read more

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Can you have ehlers danlos without hypermobile joints?

Can you have ehlers danlos without hypermobile joints?

Ehlers danlos: Yes, but it is a syndrome that has a collection of different disorders. It is usually associated with hypermobile joints so to have ehlers danlos without that clinical finding is less likely. ...Read more

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Hyperflexible joints, but no dislocations; thin, elastic skin w/ atrophic scars, but bruising regular; poor circulation; GI issues; ehlers danlos?

Hyperflexible joints, but no dislocations; thin, elastic skin w/ atrophic scars, but bruising regular; poor circulation; GI issues; ehlers danlos?

Could be: There are multiple types of ehlers danlos that vary in symptoms and severity. It is am inherited disorder so you should see a family history of similar symptoms. ...Read more

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Is osteogenesis imperfecta brittle bone disease?

Is osteogenesis imperfecta brittle bone disease?

Yes: They are the same - caused by a genetic mutation. ...Read more

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Relationship between ehlers danlos sysndrome and multiple myeloma?

Relationship between ehlers danlos sysndrome and multiple myeloma?

Doubtful connection: I am unaware of any direct connection between these two conditions. ...Read more

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Positive, intense uptake on bone scan, lose spinal hardware, bone marrow edema , family history, paternal taking Forteo to strengthen bones. ??ideas?

Positive, intense uptake on bone scan, lose spinal hardware, bone marrow edema , family history, paternal taking Forteo to strengthen bones. ??ideas?

For one: You probably should remove the hardware. Increased uptake is informing you there is bone activity. You don't state on what phase. This could indicate a fracture or infection.... The doctor should have a clinical suspicion of what he is looking for. If removing the hardware a bone biopsy can be performed if suspecting infection. ...Read more

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Is having abnormal bones (weak bones or fragile) a disability?

Is having abnormal bones (weak bones or fragile) a disability?

NOT NECESSARILY: Which study found the abnormal bone --> x-ray or nuclear medicine bone scan or bone densitometry? We have to have a specific diagnosis before we can say a disability or no disability. ...Read more

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How do people with osteogenesis imperfecta (a.K.A, brittle bones) deal with their sexual needs?

Not usually a proble: Generally, people with this condition carry out normal lives with regards to daily activities. ...Read more

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What is degenerative sacroiliac changes with vacuum phenomenon in SI joints, spurs anteriorly and sclerosis, also have thoracic bone spurs and fusion?

What is degenerative sacroiliac changes with vacuum phenomenon in SI joints, spurs anteriorly and sclerosis, also have thoracic bone spurs and fusion?

?Spondyloarthrpathy: Sounds like markers for a spondyloarthropathy. Without further history and physical exam can not state which, but you need to see a Rheumatologist who knows and knows what further studies are warranted. ...Read more

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What is the difference between benign hyper mobile joint syndrome (dx'd by rheumy)and ehlers danlos . Have chronic joint/ muscle pain and fatigue. ?

What is the difference between benign hyper mobile joint syndrome (dx'd by rheumy)and ehlers danlos . Have chronic joint/ muscle pain and fatigue. ?

Opposite spectrum: A connective tissue disease or CTD is any disease that has the connective tissues of the body as a target of pathology. Ehlers-Danlos Syndrome (EDS) is a severe type that has an actual series of gene mutations associated. It can be fatal. Hypermobile joint, fibromyalgia, chronic fatigue, these are debilitating and chronic but not likely fatal or nearly as life concerning as EDS. ...Read more

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Weak wrists signs of growth plates?

Growth Plates: I am unsure what you mean by "weak wrists". The growth plates in your wrist close when you're a teenager. Usually weakness in the wrists isn't associated with the growth plates. ...Read more

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Is acquired hypermobility of joints worse than being born w hypermobile joints as far as stability, etc.?

Is acquired hypermobility of joints worse than being born w hypermobile joints as far as stability, etc.?

Unusual: ' lax' joints ( multiple ) is very unusual in older adults unless: you were 'born' w/ them and just have recently been diagnosed or you have sustained injuries to your joints( esp. The knee) and your joint has become unstable ; or you have developed arthritis( 'knock - kneed") of your knee as you have aged and your knee joint and ligaments about them have become 'stretched ' and loose. See ors.Gl! ...Read more

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