Doctor insights on:
Viral insertion: DCIS is the earliest phase of transformation to malignancy developing in the ductal system before invasion into parenchyma has occurred. It is defined on mammo by clustered microcalcification. In general the long terminal repeat of the MMTV viral genome enters the ductal cell to initiate transformation. with time the cells become aggressive and invade basement membrane helped by the EBV virus ...Read more
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Right renal cell carcinoma extensive retroperitoneal lymphadenopathy IVC & renal vein infiltration. Can you tell stage or prognosis from this report?
Poor: This is high stage disease with a poor prognosis. ...Read more
Father65,biopsy result of nasal polyps- Moderately differentiated infiltrating keratinizing squamous cell carcinoma with areas vasaloid. is it cancer?
RT NEPRECTOMY CLEAR CELL RENAL CARCINOMA(FUHRMAN GRADE 2) CONFINED TO KIDNEY.URETER RESECTION MARGIN, SINUS & HILUM , ADRENAL FREE FROM TUMOR?
Unclear: Sorry I am unclear as to what your question is. Please clarify. ...Read more
Genetic component?: There could be genetic component to a squamous cell cancer, although the exact implications on treatment aren't known. Obviously if there is a strong family history of cancers, or if it strikes someone who is young and/or a non smoker/drinker i would suspect a strong genetic contribution. Without more details, it is hard to say with any certainty. ...Read moreSee 1 more doctor answer
Invasive non keratinizing squamous cell carcinoma tongue showing nests of malignant squamous cells grade 3 prognosis?
Can be cured: If no nodes palpable and lesion localized, RT chemo can reduce size and position site for curative resection. Partial glossectomy after initial therapy. If larger and not responsive to chemo, Ive used hight dose MTX with citrovorum factor over 12 hrs. Most effective in presence of nodal disease Basic chemo is Platinum/Taxol + RT ...Read more
Many organs: The first likely tissue where metastases occurs in invasive ductal cancer is the lymph nodes on the armpit or behind the chest wall. Other organs may include the bones, lungs, liver, brain, adrenal glands, skin, bone marrow, the lining around the lungs or heart or the abdomen. Other parts of the body are less often sites of spread. ...Read more
Colonscopy&then pathlogy report: mild oedema and lymphocytic infiltration focally forming dense aggregates&focal surface ulceration is it tumor tissu?
What does each word/phrase mean?Infiltrating, well differentiated adenocarcinoma; carcinoma focally invades superficial submucosa;no lymphovascular invasion?Is surgery advised for this type of report?
Biopsy report of buccal mucosa: infiltrating moderately differentiated keratinizing squamous cell carcinoma. What does this means.?
Needs treatment: Means you have cancer of oral cavity ( buccal mucosa ) from your description appear to be localised you will have good prognosis needs further work up for staging &care , by surgical excision for localized small area, or chemo radiation , discuss with your physicians and please do not delay . Good luck. ...Read moreSee 1 more doctor answer
Can stage 1a endometrial cancer (removed) spread to mediastinal, bilateral hilar and virchow's node w/o infiltrating another organ?
Yes but: It could possibly spread to local lymph node but the chances are very low. The lymph nodes that are in thoracic cavity are even less likely to contain metastatic tumor from a stage 1a endometrial cancer, especially if it's a garden variety low grade lesion. In fact, long term survival is very good, like 95%. The other 5% may represent very high grade tumors. ...Read more
Highly Variable: The risk of breast cancer growing outside of the breast is most dependent on the aggressiveness of the cancer and the stage at diagnosis; it is less related to the type of breast cancer (ductal, lobular, etc). While metastatic disease may be present at the time of diagnosis, a majority of breast cancer patients never develop metastases. ...Read moreSee 2 more doctor answers
No: The description you provided is not consistent with a diagnosis of carcinoma. It is more consistent with changes due to chronic inflammation. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, low fat milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more
Not yet: Hyperplasia is a lot of benign cells that are not yet malignant. Metaplasia is transformation of one benign cell type into another benign cell type. "dysplasia" or "atypical hyperplasia" would be a warning of premalignancy. The chronic inflammatory cells are not cancer. This is a benign biopsy -- either no cancer or it was not at the biopsy site. Please follow up as appropriate. ...Read more
Are carcinoid tumors carcinoma? Is malignant metastatic stomach carcinoma that's hereditary a carcinoid cancer? carcinoid Neuroendocrine tumors?
What it means?cervical/endocervical trans zone mucosa show high grade squamous intrapithelial lesion CIN2-3 with focal prominent glandular involvement
It depends: Breast cancers come in many "flavors", and this will determine the treatment. Usually it's a form of chemotherapy given by mouth or by vein. Xeloda is given by mouth, and there are many intravenous chemotherapies. Sometimes hormone blocking medications are very effective if the cancer has the estrogen or Progesterone receptor on its surface. Herceptin (trastuzumab) is useful if it has her2 on its surface. ...Read moreSee 2 more doctor answers
Fluid in the tissues, either caused by something local to the swollen area like an injury or inflammation, or from the body's retention of water. Gravity brings the fluid to the feet & legs in that case. As a general rule, if one foot is swollen, something is wrong with the foot. If both feet are swollen, it's not the feet, but water ...Read more
Swelling is the enlargement of organs, skin, or other body parts. It is caused by a buildup of fluid in the tissues. The extra fluid can lead to a rapid increase in weight over a short period of time (days to weeks). Swelling can occur all over the body (generalized) or only in one part ...Read more