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Doctor insights on: Edema Ankles Joint Pain Elevated Sed Rate

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Dr. Stephen Scholand
3 doctors shared insights

Edema (Definition)

Fluid in the tissues, either caused by something local to the swollen area like an injury or inflammation, or from the body's retention of water. Gravity brings the fluid to the feet & legs in that case. As a general rule, if one foot is swollen, something is wrong with the foot. If both feet are swollen, it's not the feet, but water ...Read more


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Can untreated hypothyroidism cause excruciating joint pain, especially in the ankles. Can it cause sed rate and CRP to be high.

Can untreated hypothyroidism cause excruciating joint pain, especially in the ankles. Can it cause sed rate and CRP to be high.

No: It will not elevate the sed rate and crp. The joint pain of severe hypothyroidism is low grade and not excruciating. There is another cause and it isn't thyroid. See a rheumatologist. The one exception is an increased risk of pseudogout which can cause major pain but is unlikely to involve the ankles. ...Read more

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Joint pain in knees,left ankle & left elbow. I'm 32 & my c-reactive was 1.4, RA factor <10, uric acid 4.7, sed rate 6, pos ANA 1:40 homogeneous. Clue?

Joint pain in knees,left ankle & left elbow. I'm 32 & my c-reactive was 1.4, RA factor <10, uric acid 4.7, sed rate 6, pos ANA 1:40 homogeneous. Clue?

Pain : It may be minor inflammation of the jts. Which does not produce positive blood tests. I would try an anti-inflammatory, Aleeve 400mg daily with food for 10 days. If this does not help I would see your physician again ...Read more

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I am 49 and found out my sed rate is 39. I have joint pain and swelling. I also have small fiber neuropathy. Is this something to worry about?

I am 49 and found out my sed rate is 39. I have joint pain and swelling. I also have small fiber neuropathy. Is this something to worry about?

See a Doctor: Joint pain and swelling is something that you should check with your doctor esp when the ESR is elevated as well. There are many details I do not know here -- which joint is one example... See your doctor or a rheumatologist. ...Read more

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Ra for 13yr controlled w/methotrexate 25mg weekly since may 2005. Diffuse joint pain since aug., sed rate/crp normal, no swelling, ruled out neuropat

Ra for 13yr controlled w/methotrexate 25mg weekly since may 2005.  Diffuse joint pain since aug., sed rate/crp normal, no swelling, ruled out neuropat

Not clear yet.: A complete history and physical examination are appropriate for all patients presenting with polyarticular joint pain since this symptom may be the initial manifestation of a systemic illness. ...Read more

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Why do I feel joint pain if my sed rate is normal?

Why do I feel joint pain if my sed rate is normal?

It is not specific: The erythrocyte sedimentation is a measure inflammation that is not specific to joint pain, so it is possible to have a normal "sed rate" and still have joint pain. Secondly, the sed rate is not the most sensitive measure of inflammation. The c-reactive protein is a measure that responds more readily to the presence and absence of inflammation for any reason. ...Read more

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What about a low sed rate? Lots of chronic fatigue, high hemoglobin and hemacrit, confusion, memory loss and now stiff body and joint pain.

What about a low sed rate? Lots of chronic fatigue, high hemoglobin and hemacrit,  confusion,  memory loss and now stiff body and joint pain.

Not a problem : There is no disease associated with a low ESR. An elevated ESR is a nonspecific indicator of inflammation. There are many possible of a high ESR--infection, malignancy, or autoimmune disease. ...Read more

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Severe joint pain in hands and feet and morning stiffness. Sed rate is norm. So no inflammation. So why do they hurt?

Severe joint pain in hands and feet and morning stiffness. Sed rate is norm. So no inflammation. So why do they hurt?

Don't assume ...: That there is no joint inflammation because sed rate is normal. It's unclear from your note how long you have been experiencing severe joint pain; in the early stages of joint inflammation the sed rate may be normal and even the finding of joint swelling can be subtle. You are in the age group in which Rheumatoid Arthritis may occur. A more sensitive marker for inflammation is the CRP; ask MD. ...Read more

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Penny has RA and is on Orencia (abatacept) and methotrexate. Recent increase in joint pain along with low energy. Blood work says high WBC and high SED rate of 50?

Penny has RA and is on Orencia (abatacept) and methotrexate. Recent increase in joint pain along with low energy. Blood work says high WBC and high SED rate of 50?

Rheumatoid Arthritis: can sometimes be a tough condition to treat. Methotrexate is an excellent medication for RA but sometimes may need dose adjustments or adjunct treatment. Increasing joint pain and low energy are possible signs that the rheumatoid is not under control. A visit to the rheumatologist or treating physician is needed. ...Read more

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I have been having lots of joint pain, tingling, and ringing in ears. Sed rate 30, CRP 2.5, cardio CRP 32.3, ANA negative. Could it be lupus or?

I have been having lots of joint pain, tingling, and ringing in ears.  Sed rate 30, CRP 2.5, cardio CRP 32.3, ANA negative.  Could it be lupus or?

Lab data: Cannot comment on lab tests removed from the clinical assessment of a patient have no access to examine and extract full medical history. Lupus is less likely with negative ana, but not impossible. See a rheumatologist. ...Read more

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What can cause low vitamin d , high sed rate positve ANA daily headaches fatigue joint pain slight vision chance and loss of balance?

What can cause low vitamin d , high sed rate positve ANA  daily headaches fatigue joint pain slight vision chance and loss of balance?

Make diagnosis: Those are a lot of things and they may or may not all be connected. Certainly with an elevated sed rate and a positiveana test are concerning for an autoimmune condition, such as lupus, would be a concern. I would encourage you to continue work up with a rheumatologist and ultimately the single or multiple diagnosis made will aid in treatment and prognosis discussions. Thank you. ...Read more

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Is there a neurological condition that causes joint pain? I have ra, pain in multiple joints since mid-aug. Sed rate/crp nml. Per RA md pain is "neuropathic, " prescribed neurontin-not working.

Is there a neurological condition that causes joint pain? I have ra, pain in multiple joints since mid-aug.  Sed rate/crp nml.  Per RA md pain is "neuropathic, " prescribed neurontin-not working.

Rhematoid arthritis: As an orthopedic surgeon who treats R.A. Patients( end stage usually for joint replacement ), i would say that by definition R.A. Pts . Have joint pain because of the very nature of their diagnosis; generally not neuropathic( diabetic , for example). In my experience a negative rf, ana, etc. Early on is more common than not... Prob. A good phy. Exam to confirm dx. And nsaids would be most helpful. ...Read more

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Dr. David Schleimer
1,498 doctors shared insights

Swelling (Definition)

Swelling is the enlargement of organs, skin, or other body parts. It is caused by a buildup of fluid in the tissues. The extra fluid can lead to a rapid increase in weight over a short period of time (days to weeks). Swelling can occur all over the body (generalized) or only in one part ...Read more


Dr. Stratos Christianakis
1,189 doctors shared insights

Joints (Definition)

Joints are parts of the body, formed by the cartilage-covered ends of bones plus the strong, flexible ligaments that attach the bones to one another. Movements at the joints in the body allow the different parts of the body to move in ...Read more