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Doctor insights on: Eclampsia Antiphospholipid Antibody

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I have mild SLE (no organ involvement), only on Plaquenil (hydroxychloroquine). No antiphospholipid antibodies, high BP or f. history of blood clots. Is birth control safe?

I have mild SLE (no organ involvement), only on Plaquenil (hydroxychloroquine). No antiphospholipid antibodies, high BP or f. history of blood clots. Is birth control safe?

Probably safe: Per Uptodate Oral contraceptives containing low levels of estrogen are probably safe in patients with mild well-controlled SLE. Avoid use in pts with with increased risks of clotting. Patients with anti phospholipid antibodies, nephrotic syndrome, hx of thrombophlebitis, CAD, migraines, smokers. uncontrolled HTN. Of course weigh the risks and benefits with your personal Doctor. ...Read more

Dr. Adam Lewis
27 doctors shared insights

Antiphospholipid Antibody (Definition)

Antiphospholipid syndrome (APS) is a disorder of blood coagulation related to the presence of autoantibodies called lupus anticoagulant and anticardiolipin. APS can cause blood clots, which most often occur in the deep veins of the legs, a condition called deep vein thrombosis. Blood clots can increase the risk for stroke and pulmonary embolism (clots in the lungs). Patients with APS are also at high risk for pregnancy complications, including miscarriage ...Read more


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Could you explain what is antiphospholipid antibody test?

Could you explain what is antiphospholipid antibody test?

Auto-antibody: Antiphospholipid antibodies affect clotting of blood and cause clots to form in blood vessels. There is more than one type of test for these, one is a type of test for syphilis and others test for effects on clotting. See this site for more info. http://www.mayoclinic.com/health/antiphospholipid-syndrome/ds00921. ...Read more

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What are the common symptoms of antiphospholipid antibody syndrome?

What are the common symptoms of antiphospholipid antibody syndrome?

Antiphospholipid Ab: Antiphospholipid syndrome is a disorder in which your immune system mistakenly produces antibodies against certain normal proteins in your blood. Antiphospholipid syndrome can cause blood clots to form within your arteries or veins as well as pregnancy complications, such as miscarriages and stillbirths. ...Read more

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What is antiphospholipid antibody test? And why would anybody need one?

What is antiphospholipid antibody test?  And why would anybody need one?

Miscarriage: Apa, along with lupus anti-coagulant antibody, are two antibodies that attack the areas in the cell wall of growing tissue, especially the fast-growing placental tissue of an early pregnancy. These are newly-discovered causes for recurrent miscarriage, and are usually treated with Heparin injections and Aspirin during pregnancy. ...Read more

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How many people in america suffer from antiphospholipid antibody syndrome?

How many people in america suffer from antiphospholipid antibody syndrome?

1 -- 5%: Apa, along with lupus anti-coagulant antibody, are two antibodies that attack the areas in the cell wall of growing tissue, especially the fast-growing placental tissue of an early pregnancy. It is estimated that 1-5% of the american population has apa syndrome. ...Read more

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The antiphospholipid antibody syndrome is antibodies associated with what problem?

Miscarriage: Apa, along with lupus anti-coagulant antibody, are two antibodies that attack the areas in the cell wall of growing tissue, especially the fast-growing placental tissue of an early pregnancy. These are newly-discovered causes for recurrent miscarriage, and are usually treated with Heparin injections and Aspirin during pregnancy. ...Read more

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How long can you live with antiphospholipid antibody syndrome before something bad happens?

How long can you live with antiphospholipid antibody syndrome before something bad happens?

Miscarriage: Apa, along with lupus anti-coagulant antibody, are two antibodies that attack the areas in the cell wall of growing tissue, especially the fast-growing placental tissue of an early pregnancy. These are newly-discovered causes for recurrent miscarriage, but also place the patient at higher risk for developing a blood clot, especially with hormone use, later in life. ...Read more

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I have been diagnosed with antiphospholipid antibody syndrome. What does that mean overall?

Miscarriage: Apa, along with lupus anti-coagulant antibody, are two antibodies that attack the areas in the cell wall of growing tissue, especially the fast-growing placental tissue of an early pregnancy. These are newly-discovered causes for recurrent miscarriage, and are usually treated with Heparin injections and Aspirin during pregnancy. ...Read more

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Does anyone have information on or personal experiences with antiphospholipid antibody syndrome?

Miscarriage: Apa, along with lupus anti-coagulant antibody, are two antibodies that attack the areas in the cell wall of growing tissue, especially the fast-growing placental tissue of an early pregnancy. These are newly-discovered causes for recurrent miscarriage, but also place the patient at higher risk for developing a blood clot, especially with hormone use, later in life. ...Read more

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Is gluten free the best way to eat for someone with antiphospholipid antibody syndrome?

No: Taking away gluten would do nothing for you unless you suffer from gluten intolerance. ...Read more

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How does antiphospholipid antibody syndrome cause miscarriage?

Autoimmune: Apl syndrome is an autoimmune disease in the same general catagory as lupus. It causes abnormal blood clotting , and attacks the body to disrupt normal funtion. Not only does it affect early pregnancy but women's spllens have been removed during a pregnancy to try to keep from pg loss. You need expert maternal-fetal doctor care before and during the pg! ...Read more

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What type of hematological malignancy itself would cause elevation in Antiphospholipid antibody ( aPL ) ?

What type of hematological malignancy itself  would cause elevation in Antiphospholipid antibody  ( aPL ) ?

None: APL is more related to autoimmune disorders which may involve various target organs in the body but not to malignancy. Not all patients with this antibody become ill. You need to consult a rheumatologist if you are having symptoms. ...Read more

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How many pregnant women suffer from antiphospholipid antibody syndrome, and what is the expectancy for pregnancy outcome?

How many pregnant women suffer from antiphospholipid antibody syndrome, and what is the expectancy for pregnancy outcome?

Not common: People with this genetic disorder seem to have a higher number of miscarriages, which is what usually inspires testing for it. We treat these patients with aspirin, sometimes blood thinners and sometimes steroids. There is greater risk for prematurity and small fetuses, but under treatment, most will have successful outcomes. ...Read more

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I've had abnormal and worsening labs for 4yrs w/ increasing ANA to 1:640, homo pattern & antiphospholipid antibody, now all labs are perfect;how/why?

I've had abnormal and worsening labs for 4yrs w/ increasing ANA to 1:640, homo pattern & antiphospholipid antibody, now all labs are perfect;how/why?

Bad lab: A neg. Test when others are positive may be a lab error. These tests are difficult to perform and some of the lab methods are poor quality. Whether the test is negative or positive has no meaning if you have no symptoms. Don't get hung up on a lab result. There are many people who have had positive tests like yours with no illness. The more important issue is do you have any signs of disease. ...Read more

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Does antiphospholipid antibody syndrome cause weakness and fatigue?

Does antiphospholipid antibody syndrome cause weakness and fatigue?

Yes: Yes it can cause vasculicitis and cause decrease in blood flow. It can predisposed to stroke. ...Read more

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31 y/o female. My CRP is 13.1 and I have antiphospholipid antibody syndrome. I am concerned that the combination of the 2 is going to cause death. I already take 10mg of coumadin (warfarin). What else to do?

Slow down: CRP can be a sign of inflammation from anything including a cold, but it isnt considered so dire without a some kind of major diagnosis being made. And for the apla the main thing is to prevent blood clots which you are doing, and unfortunately the risk of miscarriages. ...Read more

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Dr. Liawaty Ho Dr. Ho
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What could make my CRP be 13.1? 31 years old, history of antiphospholipid antibody syndrome, and a surgically removed pituitary tumor in 2012.

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
What could make my CRP be 13.1?  31 years old, history of antiphospholipid antibody syndrome, and a surgically removed pituitary tumor in 2012.

APLS: It is likely the antiphospholipid antibody syndrome that causes elevation of the CRP as low grade inflammation and immune activation occurs in apls. Having said that go to see your md and discuss more in detail with your md to rule out other infection/inflammation. ...Read more

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How risky is attempting pregnancy at the age of 40, mild lupus, antiphospholipid antibody syndrome currently taking coumadin (warfarin)?

How risky is attempting pregnancy at the age of 40, mild lupus, antiphospholipid antibody syndrome currently taking coumadin (warfarin)?

Risks are low!: I do not see major risks in becoming pregnant, that is if you get pregnant. You will be switched to heparin, probably once daily lovenox (enoxaparin). But your lupus can be managed successfully during pregnancy, and the hughes syndrome should be a non-issue if on an anticoagulant. Hope you achieve your goal! ...Read more

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Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


Dr. Rebecca Gray
162 doctors shared insights

Eclampsia (Definition)

Seizures that occur during a woman's pregnancy or ...Read more