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Doctor insights on: Duragesic Of Drugs That Increase Narcotic Effects

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Does Neurontin (gabapentin) increase the effects of methadone?

Does Neurontin (gabapentin) increase the effects of methadone?

Pain meds: Neurontin (gabapentin) is a neuropathic membrane stabilizing medicine that works on neuropathic or nerve pain. It has a different mechanism of action from methadone, which is a narcotic. Many people consider Methadone one of or the most dangerous narcotic because it is linked to abnormal heart rhythms and sudden death. It has a black box warning from the fda stating this. Whatever you can do try to reduce it. ...Read more

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Narcotic (Definition)

A natural or synthetic alkaloid compound that has morphine-like qualities. Other examples are codeine, heroin, Meperidine (demerol). They are classified based on their intrinsic activity & where they interact in the central nervous system. They are involved in pain transmission ...Read more


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Tolerance of Valium -are CNS depressant qualities of this drug also tolerance forming, or just anxiolytic effect?

Tolerance of Valium -are CNS depressant qualities of this drug also tolerance forming, or just anxiolytic effect?

Valium tolerance: When valium induces tolerance, this includes all its cns-depressant effects. It's similar to alcohol, where someone could appear "sober" despite having a high blood alcohol level. If the blood alcohol level dips from usual, withdrawal symptoms may be experienced. ...Read more

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Can taking loperamide increase the effects of hydrocodone?

Can taking loperamide increase the effects of hydrocodone?

Not really: Both will slow down your bowels, possibly causing constipation, but loperamide will not make the effects of hydrocodone (in terms of pain relief) any stronger. ...Read more

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Can ativan (lorazepam) increase the effects of tramadol?

Can ativan (lorazepam) increase the effects of tramadol?

Probably: Tramadol is used for pain relief and has less addiction risks than narcotics. Pain can cause anxiety and vise versa. I believe that ativan, (lorazepam) a benzodiazepine that decreases anxiety, can increase effects of tramadol. Reisk of abuse increase though! ...Read more

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What are long term use of narcotic pain medication adverse side effects?

What are  long term use of narcotic pain medication adverse side effects?

Multiple: Constipation; liver or kidney damage; mental & personality changes; decreased pain controll through decreased opiate receptors for the drug to attach to; and decreased productivity and rehab potential. These are just a few. ...Read more

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Safety and side effects of mixing certain perscription drugs with guanfacine?

Safety and side effects of mixing certain perscription drugs with guanfacine?

Ask pharmacist: This cannot be answered well without knowing which prescription drugs you are talking about. www.drugs.com is a helpful website and you can also ask a pharmacist to see what drugs are not compatible when taken together. In general it is not wise to "mix" drugs. ...Read more

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What are the effects of a hydrocodone and lyrica (pregabalin) overdose?

What are the effects of a hydrocodone and lyrica (pregabalin) overdose?

Depressed breathing: which can ultimately lead to coma, brain damage and death. This is mostly from the hydrocodone, but Lyrica (pregabalin) has sedative effects and will contribute to it. In addition, almost all hydrocodone containing pills have acetaminophen (tylenol) in them, and tylenol overdose can cause massive liver failure and death as well. If you are thinking about this, call your doctor or a suicide hotline immediately ...Read more

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Do drugs like viagra (sildenafil) counteract the sexual side effects of suboxone?

Do drugs like viagra (sildenafil) counteract the sexual side effects of suboxone?

Yes: All opiates have, as a side-effect, sexual dysfunction. If the problem involves maintaining an erection, medications like viagra, Cialis and Levitra (vardenafil) can help. Others complain that they have problems achieving orgasm with opiates, viagra will not help this. Opiate use, especially long term can result in problems with one's testosterone level. There is a blood test and treatment for low testosterone. ...Read more

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What are the negative effects of hydrocodone recreational use?

What are the negative effects of hydrocodone recreational use?

Sarcopenia: Sarcopenic obesity - loose essential muscle, put more body weight especially in the middle of the body with stick arms and legs. If you are a kid affects growth plate so will be short. ...Read more

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Any side effects of methadose (methadone)?

Any side effects of methadose (methadone)?

See below: Call your doctor at once if you have any of these serious side effects: •shallow breathing; •hallucinations or confusion; •chest pain, dizziness, fainting, fast or pounding heartbeat; or •trouble breathing, feeling light-headed, or fainting. Less serious side effects of Methadone may include: •feeling anxious, nervous, or restless; •sleep problems (insomnia) •feeling weak or drowsy;. ...Read more

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What are the side effects of using norco (hydrocodone and acetaminophen)?

What are the side effects of using norco (hydrocodone and acetaminophen)?

Several effects: Norco is a combination of hydrocodone and acetaminophen. Other trade names are vicodin and lorcet. Side effects of hydrocodone are similar to other narcotic pain medications: nausea, constipation, development of tolerance if used for prolonged periods. Acetaminophen has few side effects, but can lead to liver damage or liver failure if taken in excessive quantities over a short time. ...Read more

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Could alcohol and cigarettes increase the drowsiness side effect of clozapine?

Could alcohol and cigarettes increase the drowsiness side effect of clozapine?

Alcohol and clonazep: Both alcohol and Clonazepam get metabolized in the liver using same pathway. Not only it will add to the sedation, the practice is very risky. I have not heard that tobacco could increase the sedative effect of the drug. ...Read more

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Are all NSAID drugs equal in analgesia effect for pain?

Are all NSAID drugs equal in analgesia effect for pain?

NSAIDS: Most NSAIDS have equal effects. Toradol may be slightly stronger. All of them can worsen kidney function or cause stomach irritation. Be careful. ...Read more

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What are the effects of smoking Suboxone or methadone?

What are the effects of smoking Suboxone or methadone?

Don't: Neither substance should have a high effect when smoked/burned. On the other hand, the things that go to make a pill aren't meant to be inhaled and are liable to cause irritation to mouth, throat and lungs. ...Read more

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Does naltrexone (revia) block the effects of marijuana?

Does naltrexone (revia) block the effects of marijuana?

Apparently not: Although there are some overlapping interactions between the system that marijuana affects and opioid systems that Naltrexone affects, the evidence i could find--and there are some studies--seems to suggest that Naltrexone does not block the effects marijuana. ...Read more

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Dr. David Sherer
225 doctors shared insights

Duragesic (Definition)

Duragesic is a drug that increases narcotic effects which is a ...Read more


Dr. James Henning
718 doctors shared insights

Fentanyl (Definition)

Fentanyl is a ...Read more