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Doctor insights on: Duloxetine

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Cymbalta (Definition)

Cymbalta (duloxetine) is an "antidepressant" medication. However, it is an approved treatment for a variety of indications to include (unipolar) depression, anxiety, and chronic pain (related to diabetic neuropathy, musculoskeletal and/or fibromyalgia). Pharmacologically, it primarily enhances 2 different neurotransmitters (serotonin and norepinephrine). It can cause a ...Read more


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Is it okay for my dentist to prescribe duloxetine/cymbalta for tooth pain?

Is it okay for my dentist to prescribe duloxetine/cymbalta for tooth pain?

Not recommended: Cymbalta (duloxetine) is a drug prescribed for neuropathic pain (e.g. diabetic neuropathy) or any other chronic pain. Dental pain is considered acute pain and common painkillers meds are NSAIDs, Tylenol and opioids..Maybe you have a peripheral neuropathy near your tooth that mimics toothache? ...Read more

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Is it effective to take duloxetine/cymbalta 60mg for anxiety?

Is it effective to take duloxetine/cymbalta 60mg for anxiety?

Cymbalta can calm: Cymbalta is fda approved for the treatment of anxiety in adults and in my experience it is quite effective. ...Read more

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Is it safe to take duloxetine along with klonopin?

Is it safe to take duloxetine along with klonopin?

Yes: There are no drug-drug interactions between Cymbalta and klonopin. These medications are used together frequently in psychiatric practice. ...Read more

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How dangerous is it taking 60mg of duloxetine together with amphetamine daily? Just enough for energy throughout the day.

How dangerous is it taking 60mg of duloxetine together with amphetamine daily?  Just enough for energy throughout the day.

Work with MD: There is an increased risk for higher blood pressure, rapid heart rate and very rarely seizures. These are dose related. You did not mention the dose of amphetamines. I do use this combination, if needed. You should be monitored regularly by your doctor. ...Read more

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Im 26 y old i take cymbalta (duloxetine) 60mg and neurolith 400mg every night for 6 month. Will be there any side effects on me if i stop it?

Possibly: You do not indicate why you are taking these medications or for how long. It is not wise to discontinue any medication without discussing it with your doctor. ...Read more