Doctor insights on:
Drug Induced Lupus In Children
There are major differences between what I call while lupus and drug-induced lupus. Basically these are illnesses with some similar manifestations and clinical manifestations. Some of the manifestations like rashes and joint pain can occur in both, but kidney involvement is notfound with drug-induced lupus. There are other differences also but this is one of the ...Read more
See below: Most common drugs involved in drug induced lupus are isoniazid, used to treat Rbc ;hydrazine, used to treat hypertension; and procainamide used In cardiology. Less common are sulfasalazine, quinidine, penicillamine, minocycline, methldopa, and chlorpromazine. Some of the current biologics have also been implicated. ...Read more
Yes: There are certain medications that cause lupus like illness this type of lupus is not like regular systemic lupus erythematosus. If you stop the drug that causes drug induced lupus the lupus usually resolves. Regular lupus has many manifestations not seen in regular lupus especially kidney involvement and neurological involvement. They also have different laboratory tests. ...Read more
Different types: The classic drugs are medications that are used for treatment of things like heart probelms (procanamide), blood pressure (hydralazine), seizures (dilantin), etc, but not everyone who uses these drugs get drug induced lupus. Recently some of the biologic drugs that are used to treat rheumatoid arthritis can cause a lupus liek syndrome. Usually stop the drug and the drug induced lupus resolves. ...Read more
There are about 30 o:
Common drugs include medications that are used less frequenty now:
Hydralazine - a blood pressure medication;
Isoniazid - an antituberculosis medication;
Procainamide - an anti arrhythmia drug
minocycline - an antibiotic
pyrazinamide - an anti tuberculosis drug
these are a few. A recent entry into the field are the biologics that are used to treat rheuamtoid arthritis. ...Read more
Search the web: Google the term and you will find the complete list. ...Read more
Drug side effect: Some medications can cause those who take them to develop symptoms that look exactly like lupus. Stopping the offending drug usually fixes the problem. ...Read more
Lupus like caused by: There are major differences between what I call while lupus and drug-induced lupus. Basically these are illnesses with some similar manifestations and clinical manifestations. Some of the manifestations like rashes and joint pain can occur in both, but kidney involvement is notfound with drug-induced lupus. There are other differences also but this is one of the main ones to discuss ...Read more
Within 6 mo.: Within six months or sooner.Get a more detailed answer ›
Very different: There are differences - especially less kidney involvement, different serology to name some things. It mostly resolves after stopping the drug involved. ...Read more
Three worth knowing: Isoniazid, Procainamide and Hydralazine are the three to remember. The latter two are largely superseded by newer medications. There's a bunch of others reported; http://www. Nlm. Nih. Gov/medlineplus/ency/article/000446.Htm gives a pretty good list, I had a case with phenytoin, and there's nothing magic about "38". New ones will appear over time. ...Read more
Much different!: First, your clinical sx are more important than the labs. Drug-induced sle is characterized by single-strand anti-da abs. Markers for possible pss include scl-70 and centromere antibodies. But where you on a drug which commonly caused drug-induced sle. What are your symptoms: fever, joint pain, pleuritis, pericarditis? Or do you have raynaud's, swallowing probs, etc. See a rheumatology expert! ...Read more
Should people diagnosed with sle or discoid lupus avoid taking the drugs associated with drug-induced lupus?
If possible: Certain drugs can affect lupus so if there is a choice it may be prudent to avoid three drugs however depending on your circumstance there may not be other options. If you must take a drug associated with lupus be vigilant in reporting any joint pains, fever, or unusual symptoms to your doctor. ...Read more
Are there any documented cases of drug induced Lupus caused by Aspirin and if so how long after discontinued do symptoms subside?
Do anti-histone antibodies appear exclusively in drug-induced lupus or can they appear in SLE & other disorders as well?
SLE: These antibodies are more common in drug induced lupus but occur in garden variety SLE as well. ...Read more
Not really: It can cause several different side effects but Lupus is not one of them ...Read more
Had drug induced lupus now resolved, still get very cold hands & feet etc I noticed today that now my fingertips are wrinkled from cold. Why is this?
? Raynauds: It may be raynauds disease especially if your hands blanch or turn blue with cold exposure. ...Read more
+ANA test. Elevated histones AB only. Only on aspirin and BB. Take some supplements in low doses like serrapeptase. Can this cause drug induced lupus?
Not known: I am not aware that this is associated with drug-induced lupus. Antihistone anybody's can be seen in wild or systemic lupus as well as drug-induced lupus. Certainly there is no evidence from what you tell us that you have lupus of any type. You say you're on aspirin and I'm uncertain why and you say are on BB and I don't know what that is. From the information you're giving us I'm not certain the information you're giving us I'm not even certain why they did it in a testing on you. From what I can tell you don't have Lucas from this conversation ...Read more
My doctor put me on minocin (minocycline) for my acne but I'm nervous of side effects and drug induced lupus. Are these very rare? I've been on this drug years ago.
Good choice: Acne is a serious, chronic disease that is a major personal and professional liability. Minocycline very seldom causes problems and when it does, discontinuing the medicine and replacing it with something else is easy and you'll heal up fine. Nothing worthwhile in life is risk-free. ...Read more
3 years ago I had drug-induced lupus but I still feel very unwell: severe pain, fatigue, cold sensitivity, swollen glands & more regularly. What to do?
Drug-induced lupus: See a rheumatologist and get fully evaluated. This may or may not be related to the former drug-induced condition but certainly deserves a thorough assessment. Good luck. ...Read more
Could Humira (adalimumab) cause drug-induced lupus on the head? Some small lesions on the head. (Rheumatoid arthritis)
Can help more often: Chemotherapy can help treat lupus but certain drugs may provoke lupus. Most of the drug induced lupus cases are not wild lupus as these are actually a different type of lupus we call "drug induced lupus".Although unusual certain chemotherapeutic agents have a potential to cause drug induced lupus ...Read more