Doctor insights on:
Drug Half Life
Taking a short half-life drug(venlafaxine) at bed time
does waste it?I think 150mg at morning is better than 75mg morning&bed time.
Not wasted: The effects of antidepressants don't depend on their elimination half-lives. Long term changes occur in cells as a result of ongoing exposure to the med. Half-life issues have more to do with immediate side-effects. That said, venlafaxine (effexor) is usually prescribed in time-release versions ("xr") now, to spread absorption over the day. In this case either dosing approach is similar. ...Read more
Does 50 mg of modafinil(half of prescribed dose) is effective for drowsiness?.Drug tolerance chance?.Elimination half life?I will start tomorrow.
Dose may be low: The dose maybe somewhat low. Comes in 50s, 150s and 250 in the us. The half-life is 12 to 15 hours. I do not generally encounter tolerance developing to this medication. The only exception to that rule might be someone with idiopathic central nervous system hypersomnolence. Best wishes and i hope that this does a good job working on your hypersomnolence. Take care. ...Read more
Taper off gradually: It is difficult to answer what will happen as we do not know why you were put on it in first place.It is an anti depressant and has many indications.You should discuss with your doctor if you can stop it and since you have been taking it all your life as you say, you have to slowly taper it down before stopping it.Discuss with your doctors if you can come off it. ...Read more
Professional help: Very few people are able to pull themselves completely out of an addiction "spiral." Ultimately, you have to do the heavy lifting, but there are people who can help you learn to use the tools you need to get sober and remain that way. However, the route you take may depend on your drug(s) of choice. Check online on chemical dependency programs in your area. There are also self-help programs-AA/NA ...Read moreSee 2 more doctor answers
My life is in jepordy, i need to lose weight and i don't have the will power i need a rehap food is like a drug to me. Help?
Losing weight: To lose weight, get ur resting metabolism rate done(weight loss centers do this). This determines the total number of calories you need to lose 1-2lbs/week. Decreasing 500cal/day will give you a 1lb wt loss in 1wk; drink water (1/2 your body weight), eat small meals about 150-200cal 2-4x/(depending on your metabolism rate) and 500cal/meal at night: lean protein/veggies; avoid carbs, . ...Read more
Progressive onj has changed my life. Is there any experimental drugs or procedures a person can volunteer for to help stop this nitemare for others?
Not definitive : Unfortunately, the onj (or bronj) is a very painful and dragging condition. There are different theories for explaining what is happening in the jaw bone from surface infection, to metabolic changes, to flipping surface electrical charges in the bone ) . But nonetheless, no actual, effective, or specific , direct treatment is founmd yet. There are preventive measures available though ... ...Read moreSee 1 more doctor answer