Top
30
Doctor insights on: Drug Femara Letrozole

Share
Dr. Jerome Zacks
80 Doctors shared insights

Letrozole (Definition)

Letrozole is a commonly used medicine for the prevention/treatment of certain types of breast cancer. It is a safe medicine. It prevents the conversion of male to female hormones. It is also commonly used now for fertility treatment. It can help ovulation and can help a woman make an extra egg sometimes. It is often used instead of Clomid (clomiphene) for fertility treatment ...Read more


2

2
How helpful is the fertility drug femara (letrozole)?

Very helpful: Femara or Letrozole is an oral ovulation induction medication. It works sometimes when Clomid (clomiphene) doesn't. It also helps pregnancies to occur when Clomid (clomiphene) fails. It seems to be very helpful especially in patients with pcos. The pregnancy rates are similar to Clomid (clomiphene) but the side effects are less and the multiple pregnancies seem to be also less. ...Read more

3

3
Is it safe to have surgery while using the drug femara (letrozole)?

Probably: Almost certainly yes, but to be specific i'd ask 1) what surgery?) and 2) why are you using femara (letrozole)? If in doubt, ask your surgeon. ...Read more

4

4
How good is the cancer drug femara (letrozole)?

How good is the cancer drug femara (letrozole)?

A good drug: It is used to prevent recurrence of breast cancer after surgery. It also is an effective treatment for hormone receptor positive recurrent breast cancer. ...Read more

5

5
How effective is femara (letrozole) drug instead of chemotherapy in a person with low platelets?

How effective is femara (letrozole) drug instead of chemotherapy in a person with low platelets?

Not related: The effect of Femara (letrozole) or of chemo on the cancer is unrelated to the platelet count. The choice between the two has to do with clinical characteristics of the cancer and the patient, not the blood counts. That said, if a patient's platelets are too low, it may not be possible to give chemo but that has to do with side effects, not effectiveness against the cancer. ...Read more

6

6
Is femara (letrozole) used as a fertility drug?

Is femara (letrozole) used as a fertility drug?

Yes: Although Femara (letrozole) is only fda approved for the treatment of certain types of breast cancer, it is also used off-label to stimulate ovulation in fertility treatments. It is sometimes used in the place of clomifene (clomid) for ovarian stimulation. ...Read more

7

7
Femara (letrozole) is metabolized in liver by cytochrome p450 system. Astaxanthin says "use cautiously w drugs metabolized by liver's cytochrome p450 enzyme system; does this mean don't use astaxanthin w femara (letrozole)?

Femara (letrozole) is metabolized in liver by cytochrome p450 system. Astaxanthin says "use cautiously w drugs metabolized by liver's cytochrome p450 enzyme system; does this mean don't use astaxanthin w femara (letrozole)?

Not necesarilly but: Virtually all drugs are metabolized by cytochrome p450 enzymes. Astaxanthin can stimulate these, so it could lead to lower blood levels of "certain drugs" according to http://www. Naturalmedicinejournal. Com/article_content. Asp? Article=293. I no of no evidence that Femara (letrozole) is one of the drugs it interacts with. Small amounts of astaxanthin are unlikely to have much effect. Ask the doc who prescribed it. ...Read more

9

9
What is femara (letrozole)?

Femara (letrozole): Is a non-steroidal aromatase inhibitor used to treat hormonally responsive breast cancer after surgery. Aromatase is an enzyme that converts androgens to Estrogens which then cause cells to divide. By inhibiting this enzyme, less estrogen is formed, hence less cell replication. ...Read more

10

10
What is femara (letrozole) used for?

Ovulation: In the world of fertility, it is used to induce I ovulation, very similar to clomid (clomiphene). It is, however, also used in breast cancer patients. ...Read more

11

11
Can you take femara (letrozole) with mucinix?

Can you take femara (letrozole) with mucinix?

Femara (letrozole) drug interact: I am unaware of any interaction between the 2 drugs. Mucin ex is usually given for a short time while Femara (letrozole) is commonly prescribed for 5 years, deoending on the condition. ...Read more

12

12
Is femara (letrozole) safe for young children?

Is femara (letrozole) safe for young children?

No: Why would a young child take femara (letrozole)? It is a drug used for the treatment of breast cancer in post-menopausal women. If your child (or grandchild) has taken many of your pills, you should contact your local poison control - usually by calling your local hospital emergency department. ...Read more

14

14
Is it ok to take a "vacation" from femara (letrozole)?

Is it ok to take a "vacation" from femara (letrozole)?

Discuss with you MD: It depends on what you mean by "vacation". How long you are thinking to stay off the femara (letrozole)? .
Since I don't know any other information- such as the staging- the goal of therapy, your tolerance etc, I would suggest you to discuss this matter with your oncologist. ...Read more

15

15
What are some alternate medicines for femara (letrozole)?

See full answer: Currently the alternatives to Femara (also known as letrozole) are Arimidex (anastrozole) and Aromasin (exemestane). All 3 belong to a class of medications known as aromatase inhibitors and can help reduce the risk of breast cancer recurrence. Another type of medication, tamoxifen, is known as a selective estrogen receptor modulator, or serm - it is primarily used in premenopapusal women. ...Read more

16

16
What is the definition or description of: femara (letrozole)?

Femara (letrozole): Letrozole (femara (letrozole) (r)) is a medicine that blocks the conversion of androgens in fat cells to the strong estrogen (estrone). ...Read more

17

17
What risks are associated with the long-term use of Femara (letrozole)?

Affects the bones: Femara (letrozole) tends to reduce the bone density causing osteopenia or even cause osteoporosis. So you have to have your mineral bone density measured regularly and use medicines (like bisphosphonates) to protect your bones. ...Read more

18

18
Does it matter if femara (letrozole) is taken in the morning vs evening?

No matter: There are several reasons to take Femara (letrozole) but it should not matter when you take the medication regarding the benefits of its use. It can cause symptoms with dizziness and some people choose to take it before bedtime. You should discuss your other medications with your provider, specifically if you are on thyroid or cholesterol meds, in order to determine interactions and the best time to take it. ...Read more

19

19
I have completed first cycle of femara (letrozole). But did not concieved. What can be the possible reasons. Test of my husband are normal.

I have completed first cycle of femara (letrozole). But did not concieved. What can be the possible reasons. Test of my husband are normal.

Luck, No ovulation: Femara is a good drug but if you did not ovulate then no pregnancy. Change dose is no ovulation. Luck - the success rate is about 10-15% per cycle, so try a few more cycles. Femara is not a first line drug. Clomid (clomiphene) actually works better - maybe switch or add clomid (clomiphene). Best wishes. ...Read more

21

21
How to know your ovulating on femara (letrozole)?

How to know your ovulating on femara (letrozole)?

Ovulation: Your doctor will have you get an ultrasound and/ or check with an ovulation predictor kit. ...Read more

23

23
Will I ovulate while on femara (letrozole)?

Most likely: Femara is the brand name for the drug letrozole, which is an aromatase inhibitor. This kind of drug blocks production of estrogen, making the body think it should create a surge of hormones like those that prompt ovulation. Letrozole is sometimes used in women being treated for infertility to induce ovulation. In post-menopausal women, ovulation will not occur, and Letrozole has other uses. ...Read more

24

24
Does femara (letrozole) cause osteoporosis?

Does femara (letrozole) cause osteoporosis?

Possibly: Femara (letrozole) is an aromatase inhibitor. It works by decreasing the amount of estrogen produced in post-menopasual women. Anything that lowers estrogen level will take away its protective effect on bone, thus increasing the risk of fracture, osteopenia or osteoporosis. ...Read more

25

25
Can you dissolve femara (letrozole) in water?

Can you dissolve femara (letrozole) in water?

Ask prescribing Dr.: A person who is taking Femara (letrozole) (for breast cancer) and has trouble swallowing the pill, should ask the prescribing doctor if the pill can be crushed and mixed with liquid or food. The paperwork about the drug says the drug doesn't dissolve well in water. It doesn't have a warning box saying not to crush the tablet, so probably it is ok to crush up to aid swallowing. ...Read more

26

26
Can I have wine if I'm on femara (letrozole)?

Yes if you have to h: We discourage alcohol use for patients with cancer who are taking treatment. But one glass of wine occasionally is acceptable and relatively harmless. ...Read more

27

27
What is the use of femara (letrozole) safe for children?

What is the use of femara (letrozole) safe for children?

Fulmars: This drug is an "aromatase inhibitor". It inhibits testosterone conversion. I personally do not use it because it is not fda approved and really has not been accepted as efficacious by mainstream endocrinologists. ...Read more

28

28
What are some possible side effects of femara (letrozole)?

What are some possible side effects of femara (letrozole)?

Hot flashes, etc.: The most common side effects of Femara (letrozole) include hot flashes, joint pain, headaches, back pain, and increased sweating. Less common side effects include nausea, vomiting, weight changes, and constipation. Despite this laundry list of possibilities, in reality, most people tolerate Femara (letrozole) very well. ...Read more

29

29
What's the difference between arimidex and femara (letrozole)?

Different companies: These drugs have different structures but act in the same way. Both are aromatase inhibitors. Arimidex (anastrozole) (generic name anastrazole) and Femara (generic name letrozole) may have different side effects in different women, as well as different costs. They can be used interchangeably. ...Read more

30

30
What are differences between femara (letrozole) and arimidex?

What are differences between femara (letrozole) and arimidex?

The names and doses: Femara (letrozole) and Arimidex are both aromatase inhibitors that are taken by mouth once a day. They work by prevenitg fat cells from making estrogen, which lowers total estrogen in your body. We use them identically in practice. ...Read more

Find us on Facebook