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Doctor insights on: Doxylamine Succinate Side Effects

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Hi, how likely is it to develop a tolerance to the sedating effects of doxylamine succinate when taken daily for a longer period of time?

Hi, how likely is it to develop a tolerance to the sedating effects of doxylamine succinate when taken daily for a longer period of time?

Tolerance: to doxylamine can develop overtime, needing more to have the same desired effect, interrupted use can delay that, however, it is hard to predcit which individual would develop tolerance and after how long, as metabolism differs, depending on multitude of factors in every person ...Read more

Dr. Qamar Khan
79 doctors shared insights

Doxylamine (Definition)

Doxylamine is an antihistamine which is ...Read more


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What will taking ten doxylamine succinate do?

What will taking ten doxylamine succinate do?

Not a good idea: 1 800 222 1222 is the number for poison control if this occurs and...... Have somebody take you to the emergency room to get your stomach pumped. Anticholinergic side effects can include, racing hert, pounding chest, hallucinations, seizures, dry mouth, thickened secretions. ...Read more

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Is 50 mg of doxylamine succinate safe to take for sleep?

Is 50 mg of doxylamine succinate safe to take for sleep?

Doxylamine: Doxylamine is not a sleeping medication. It is an Antihistamine which makes you drowsy Conflicts with parents, relationships with turmoil and separations, peer pressure, work and finances can cause Anxiety and sleep problem Trust your body to have sleep as it has done for 21 years Exercise in evening Use Breathing Relaxation, Visual Imagery, Tai Chi, Yoga, and Meditation, Music See a Psychiatrist ...Read more

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How much Doxylamine Succinate mg does it take to kill you?

How much Doxylamine Succinate mg does it take to kill you?

Please seek help: If you or someone you know overdosed it is contemplating overdosing please seek help immediately. Symptoms of overdose are fever, confusion, dry mouth, racing heart, and delirium. ...Read more

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Is it safe to take 1/2 a pill of doxylamine succinate every night?

Is it safe to take 1/2 a pill of doxylamine succinate every night?

Doxylamine: Doxylamine succinate trouble of the active ingredient in Unisom, is a non-habit-forming antihistamine that promotes sleep. As long as you tolerate it well, it should not hurt you to take a half a tab of that each evening, but it would be better if you could figure out a way not to take it every night. Good luck. ...Read more

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Is 50mg safe to take off doxylamine succinate? Can it cause headaches?

Is 50mg safe to take off doxylamine succinate? Can it cause headaches?

50 mg is safe: Doxylamine is an antihistamine that is prescribed for sedation. The usual doseage is 6 to 50 mg at night. Doxylamine is not addictive. Do not use it with other antihistamines or sedatives or alcohol! dry mouth or dizziness is possible; headache would be uncommon. ...Read more

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Is 50mg of doxylamine succinate safe?

Is 50mg of doxylamine succinate safe?

Yes: The FDA approved, label dosages for insomnia are from 25-50 mg nightly. We use this medication off-label routinely to treat morning sickness in pregnant women at higher doses than this. Overall it is a very safe and well tolerated medication. It can cause urinary retention in older people with prostate or bladder issues though. ...Read more

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Is doxylamine succinate habit-forming?

Is doxylamine succinate habit-forming?

Unisom: is not considered to be addictive in that there are no withdrawal side effects. Its use over a long period of time is not recommended as it has anticholinergic side effects that can interfere with memory, attention and ability to deal with outside stimuli. Do not take it with other sedatives or antihistamines like Zyrtec (cetirizine). ...Read more

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What would happen if I took 250mg of doxylamine succinate?

What would happen if I took 250mg of doxylamine succinate?

Not a good idea: Recommended dose of this antihistamine 25 mg. "Doxylamine, a first-generation antihistamine, is identified in the Beers Criteria as a potentially inappropriate medication to be avoided in patients 65 years and older (independent of diagnosis or condition) due to its potent anticholinergic properties resulting in increased risk of confusion, dry mouth, constipation, and anticholinergic effects" ...Read more

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Is it ok to take 25mg of doxylamine succinate daily before going to bed?

Sure: Depending on other medications/treatments and your prior medical history -- should be fine. Hope that helps! ...Read more

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Can you tell me what to do if i took 250 mg of doxylamine succinate will i be alright?

Can you tell me what to do if i took 250 mg of doxylamine succinate will i be alright?

Good luck: if you are fine by the time you are reading this answer,then nothing happened. doxylamine is in an antihistamine: it can make you tired, dry mouse, dizzy, etc. the effects should wear off in a few hours, if you are healthy. If you do this medication for fun – do not do it. Find some other ways to have fun. I treat a lot of patients who got hooked on medications quickly ...Read more

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Is it ok to use doxylamine succinate at 25-50 mg for more than 2 weeks. Also how long of a break is needed between 2 wks of using it? Thanks

Is it ok to use doxylamine succinate at 25-50 mg for more than 2 weeks. Also how long of a break is needed between 2 wks of using it? Thanks

Yes it is ok: Doxylamine succinate is a first generation antihistamine and is used for allergy.As compared to the second generation antihistamines like loratadine(Claritin)it will cause drowsiness.But if you can tolerate and have no side effects you can take it in dose of 25mgm longer than 2weeks..But I advice my patients to switch to second generation antihistamines like Claritin,Allegra,Zyrtec or Xyzal. ...Read more

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75mg doxylamine succinate and 9mg lunesta, (eszopiclone) is that safe?

75mg doxylamine succinate and 9mg lunesta, (eszopiclone) is that safe?

Overdosing: Are you trying to harm yourself? High doses of Lunesta (eszopiclone) do not, in any way, increase the likelihood of sleep. This dose can harm your brain and your body. Please stop. ...Read more

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Can I take my normal dose of Claritin 10mg and take alkaseltzer plus nighttime which has doxylamine succinate 6.25mg?

Can I take my normal dose of Claritin 10mg and take alkaseltzer plus nighttime which has doxylamine succinate 6.25mg?

Antihistamines: Both claritin and doxylamine are antihistamines. Claritin doesn't cause drowsiness but doxylamine can. However I wouldn't expect any adverse reactions if you took both. Your pharmacist can also give you more expert advice on this matter. . ...Read more

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Is ok to take (4) 25mg doxylamine succinate tab? I lost a loved one yesterday and I have already taken 3 and still can't relaxe enough to go to sleep

Is ok to take (4) 25mg doxylamine succinate tab? I lost a loved one yesterday and I have already taken 3 and still can't relaxe enough to go to sleep

Acute StressReaction: I feel your sadness due to loss of your loved on and feeling in a state of disbelief or overwhelmed with many emotions. Doxylamine is an antihistamine for allergy. It is not a medication for relaxation, sleep, anxiety or sadness. Be with supportive family or friends and release your feelings. Trust in Healing Powers of your Body. See a Psychiatrist, discuss Ativan or Xanax (alprazolam) and grief counseling. ...Read more

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Is diphenhydramine hydrochloride and doxylamine succinate ok together?

Is diphenhydramine hydrochloride and doxylamine succinate ok together?

Caution Required: Both drugs have similar "mechanisms of action." therefore, the effects they produce are "additive" and, in theory, can pile up to create more effects than would be predicted if each drug were taken by itself...Almost as if 1+1=3! both drugs produce sedation and have anti-histamine properties. So, excessive sleepiness or agitation can happen. Be cautious..Speak to your provider or pharmacist! ...Read more

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