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Doctor insights on: Doxorubicin Hydrochloride Medication

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Can you tell me about the long term side effects from the chemotherapy drugs adriamycin (doxorubicin) and cytoxin?

Can you tell me about the long term side effects from the chemotherapy drugs adriamycin (doxorubicin) and cytoxin?

TWO MAJOR ONES: Adriamycin (doxorubicin) and Cytoxan is a great combination regimen used in breast cancer. The major long term side effects for both of these drugs is secondary leukemias, risk is around 1%. For adriamycin (doxorubicin) there is a concern for cardiotoxicity, but risk rises with cumulative dose. Risk is less than 10%. Patients get an echocardiogram or muga scan prior to therapy to evaluate heart status. Talk to your md. ...Read more

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Dr. Gregory Moneta
17 doctors shared insights

Doxorubicin Hydrochloride (Definition)

Doxorubicin hydrochloride is a nausea and vomiting agent which is a ...Read more


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Which is the better cytotoxic drug (adriamycin (doxorubicin) or ifosfamide) for synovial sarcoma?

Chemotherapy for SS: I would potentially seek out an opinion from the mayo clinic oncology department who are not very far north of you. I can help set that up for you. Please contact me at [email protected] ...Read more

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Who should not take Adriamycin (doxorubicin)?

Adriamycin (doxorubicin): “Doxorubicin HCl is contraindicated in patients with: Severe myocardial insufficiency, Recent (occurring within the past 4–6 weeks) myocardial infarction, Severe persistent drug-induced myelosuppression, Severe hepatic impairment (defined as Child Pugh Class C or serum bilirubin level greater than 5 mg/dL) & Severe hypersensitivity reaction to Doxorubicin HCl including anaphylaxis/” See: ...Read more

Dr. Liawaty Ho Dr. Ho
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Adriamycin (doxorubicin) make you sterile?

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:

It can: It can- but that will depend on the cumulative dose given, your age when receiving the treatment, whether you also received other kind of therapy? Radiation etc. Please discuss your situation with your oncologist. ...Read more

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What side effects are associated with Adriamycin (doxorubicin)?

Tell us more about y: Please give us some background about your question. Adriamycin is a very effective drug and is widely used in oncology. It does have some serious side effects but they can be manged quite well except for Hair loss. It can cause nausea and vomiting(but it can be easily controlled with anti-nausea medication. It can also affect the heart but your oncologist will take due precuations ...Read more

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
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Does anyone know about the long term side effects from adriamycin (doxorubicin)?

Dr. Liawaty Ho Dr. Ho
2 doctors agreed:
Does anyone know about the long term side effects from adriamycin (doxorubicin)?

Possible AE's: May include infertility, heart dysfunction, bone marrow insuficiency, a second malignancy ( leukemia) - which may develop years after treatment has ended. ...Read more

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What is Adriamycin (doxorubicin) used for?

Adriamycin (doxorubicin): Adriamycin (doxorubicin) is a medication used for the treatment of cancer. ...Read more

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Can you tell me how adriamycin (doxorubicin) work in the cell?

Cytotoxic agent: It is a DNA intercalator, inhibits Topoisomerase enzymes and also chelates iron,thus producing free radicals which cause cytotoxic cell death ...Read more

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Why is adriamycin (doxorubicin) chemotherapy pushed manually rather than administered through an iv? Are premeds given with a/c chemo? If so what are they?

Why is adriamycin (doxorubicin) chemotherapy pushed manually rather than administered through an iv? Are premeds given with a/c chemo? If so what are they?

It is IV: ...Just given as an IV push instead of an IV drip to reduce, amongst other things, the risk of leakage to surrounding tissues leading to a chemical burn. The choice depends on the particular institution and the chemo protocol. As to premeds, most people use zofran (ondansetron) or one of its cousins plus steroids. Many use emend as well right from the start. If this is about you, best wishes. ...Read more

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Can adriamycin (doxorubicin) (chemo) cause neuropathy?

Yes: Doxorubicin (adriamycin (doxorubicin)) can indeed cause nerve damage, but not always the typical 'peripheral neuropathy' seen with other chemotherapy drugs. It affects the myelin sheath of nerve and ganglia and can cause 'ganglionopathy'. Symptoms include numbness/tingling in both the arms/hands and legs/feet (not just the feet). Other drugs given alongside adriamycin (doxorubicin) can add to the risk. ...Read more

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How can adriamycin (doxorubicin) (used to treat cancer) be fatal?

How can adriamycin (doxorubicin) (used to treat cancer) be fatal?

Heart damage: Adriamycan can cause damage to the heart tissue. It also lowers blood counts which can lead to life threatening infections. Your oncologist can explain how to prevent these problems. ...Read more

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What is the definition or description of: Adriamycin (doxorubicin) allergy?

What is the definition or description of: Adriamycin (doxorubicin) allergy?

Intolerance: A person is considered to have allergy to a medication if there is a sudden reaction(unexpected). The reactions to medicines typically manifest as a skin hives or a skin rash often associated WITH ITCHING. A drop in blood pressure and difficulty with breathing can also occur with severe forms of allergy called Anaphylaxis ...Read more

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How effective is doxorubicin (Adriamycin) for treating lung cancer?

Adriamycin (doxorubicin): Adriamycin (doxorubicin) is beneficial in treatment of a number of types of cancer including lung cancer. ...Read more

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Adriamycin (doxorubicin) cyclophosphamide is toxic to what besides heart?

Adriamycin (doxorubicin) cyclophosphamide is toxic to what besides heart?

Many: Side effects of this chemotherapy combination include fatigue, hair loss, nausea, vomiting, finger and toe nail changes, low blood counts. ...Read more

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Which is the better adriamycin (doxorubicin) or ifosfamide for synovial sarcoma?

Which is the better adriamycin (doxorubicin) or ifosfamide for synovial sarcoma?

Usually combined: These 2 chemotherapy drugs are usually combined in treatment of synovial sarcoma. I am not sure that one is better than the other. A study in the 1990s showed that the combination was better than doxorubicin alone. ...Read more

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Can you mix streptozocin, 5-FU (fluorouracil), and doxorubicin (adriamycin)?

Yes it can be done: These 3 drugs have been use din combination in the past. Not a great combination in general but it can be done. ...Read more

Dr. Adam Levy
23 doctors shared insights

Adriamycin (Definition)

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Dr. Jerome Zacks
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Rubex (Definition)

Rubex is a nausea and vomiting agent which is a ...Read more