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Doctor insights on: Doxorubicin Hydrochloride Medication

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Can you tell me about the long term side effects from the chemotherapy drugs adriamycin (doxorubicin) and cytoxin?

Can you tell me about the long term side effects from the chemotherapy drugs adriamycin (doxorubicin) and cytoxin?

TWO MAJOR ONES: Adriamycin (doxorubicin) and Cytoxan is a great combination regimen used in breast cancer. The major long term side effects for both of these drugs is secondary leukemias, risk is around 1%. For adriamycin (doxorubicin) there is a concern for cardiotoxicity, but risk rises with cumulative dose. Risk is less than 10%. Patients get an echocardiogram or muga scan prior to therapy to evaluate heart status. Talk to your md. ...Read more

Dr. Warren Foster
17 Doctors shared insights

Doxorubicin Hydrochloride (Definition)

Doxorubicin hydrochloride is a nausea and vomiting agent which is a ...Read more


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Which is the better cytotoxic drug (adriamycin (doxorubicin) or ifosfamide) for synovial sarcoma?

Chemotherapy for SS: I would potentially seek out an opinion from the mayo clinic oncology department who are not very far north of you. I can help set that up for you. Please contact me at David. Stockman@orthopath. Com ...Read more

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Who should not take Adriamycin (doxorubicin)?

Adriamycin (doxorubicin): “Doxorubicin HCl is contraindicated in patients with: Severe myocardial insufficiency, Recent (occurring within the past 4–6 weeks) myocardial infarction, Severe persistent drug-induced myelosuppression, Severe hepatic impairment (defined as Child Pugh Class C or serum bilirubin level greater than 5 mg/dL) & Severe hypersensitivity reaction to Doxorubicin HCl including anaphylaxis/” See: ...Read more

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What is the generic form of Adriamycin (doxorubicin)?

Adriamycin (doxorubicin): Doxorubicin is brand name of the generic Adriamycin (doxorubicin). ...Read more

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Adriamycin (doxorubicin) make you sterile?

It can: It can- but that will depend on the cumulative dose given, your age when receiving the treatment, whether you also received other kind of therapy? Radiation etc. Please discuss your situation with your oncologist. ...Read more

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What side effects are associated with Adriamycin (doxorubicin)?

Tell us more about y: Please give us some background about your question.
Adriamycin is a very effective drug and is widely used in oncology.
It does have some serious side effects but they can be manged quite well except for Hair loss. It can cause nausea and vomiting (but it can be easily controlled with anti-nausea medication. It can also affect the heart but your oncologist will take due precuations ...Read more

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How effective is Doxorubicin (Adriamycin) for treating leukemia?

Adriamycin (doxorubicin): Adriamycin (doxorubicin) is beneficial in the treatments of a number of types of cancer including leukemia. ...Read more

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Does anyone know about the long term side effects from adriamycin (doxorubicin)?

Does anyone know about the long term side effects from adriamycin (doxorubicin)?

Possible AE's: May include infertility, heart dysfunction, bone marrow insuficiency, a second malignancy (leukemia) - which may develop years after treatment has ended. ...Read more

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What is Adriamycin (doxorubicin) used for?

Adriamycin (doxorubicin): Adriamycin (doxorubicin) is a medication used for the treatment of cancer. ...Read more

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Can you tell me how adriamycin (doxorubicin) work in the cell?

Cytotoxic agent: It is a DNA intercalator, inhibits Topoisomerase enzymes and also chelates iron, thus producing free radicals which cause cytotoxic cell death ...Read more

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Can pregnant women take Adriamycin (doxorubicin)?

Adriamycin (doxorubicin): Adriamycin (doxorubicin) is FDA Pregnancy Category D (Positive evidence of risk). ...Read more

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Why is adriamycin (doxorubicin) chemotherapy pushed manually rather than administered through an iv? Are premeds given with a/c chemo? If so what are they?

Why is adriamycin (doxorubicin) chemotherapy pushed manually rather than administered through an iv? Are premeds given with a/c chemo? If so what are they?

It is IV: ...Just given as an IV push instead of an IV drip to reduce, amongst other things, the risk of leakage to surrounding tissues leading to a chemical burn. The choice depends on the particular institution and the chemo protocol. As to premeds, most people use zofran (ondansetron) or one of its cousins plus steroids. Many use emend as well right from the start. If this is about you, best wishes. ...Read more

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Can adriamycin (doxorubicin) (chemo) cause neuropathy?

Yes: Doxorubicin (adriamycin (doxorubicin)) can indeed cause nerve damage, but not always the typical 'peripheral neuropathy' seen with other chemotherapy drugs. It affects the myelin sheath of nerve and ganglia and can cause 'ganglionopathy'. Symptoms include numbness/tingling in both the arms/hands and legs/feet (not just the feet). Other drugs given alongside adriamycin (doxorubicin) can add to the risk. ...Read more

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How can adriamycin (doxorubicin) (used to treat cancer) be fatal?

How can adriamycin (doxorubicin) (used to treat cancer) be fatal?

Heart damage: Adriamycan can cause damage to the heart tissue. It also lowers blood counts which can lead to life threatening infections. Your oncologist can explain how to prevent these problems. ...Read more

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What is the definition or description of: Adriamycin (doxorubicin) allergy?

What is the definition or description of: Adriamycin (doxorubicin) allergy?

Intolerance: A person is considered to have allergy to a medication if there is a sudden reaction (unexpected). The reactions to medicines typically manifest as a skin hives or a skin rash often associated WITH ITCHING. A drop in blood pressure and difficulty with breathing can also occur with severe forms of allergy called Anaphylaxis ...Read more

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How effective is doxorubicin (Adriamycin) for treating lung cancer?

Adriamycin (doxorubicin): Adriamycin (doxorubicin) is beneficial in treatment of a number of types of cancer including lung cancer. ...Read more

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Adriamycin (doxorubicin) cyclophosphamide is toxic to what besides heart?

Adriamycin (doxorubicin) cyclophosphamide is toxic to what besides heart?

Many: Side effects of this chemotherapy combination include fatigue, hair loss, nausea, vomiting, finger and toe nail changes, low blood counts. ...Read more

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Which is the better adriamycin (doxorubicin) or ifosfamide for synovial sarcoma?

Which is the better adriamycin (doxorubicin) or ifosfamide for synovial sarcoma?

Usually combined: These 2 chemotherapy drugs are usually combined in treatment of synovial sarcoma. I am not sure that one is better than the other. A study in the 1990s showed that the combination was better than doxorubicin alone. ...Read more

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Can you mix streptozocin, 5-FU (fluorouracil), and doxorubicin (adriamycin)?

Yes it can be done: These 3 drugs have been use din combination in the past. Not a great combination in general but it can be done. ...Read more

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Cad and adriamycin (doxorubicin) for breast ca 10 yrs ago sob and fatigue er or appt?

ER: If you are short of breath, go to the ER by getting a ride or dial 911 and get an ambulance. ...Read more

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Which is the better cytotoxic drug for synovial sarcome ---adriamycin or ifosfamide?

Given together: This is an uncommon tumor. If chemotherapy is used these drugs are often give together. It would be difficult to really say that one is clearly better. ...Read more

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Why does doxorubicin (cancer drug) have a greater effect on heart?

Myocyte damage: Adriamycin (doxorubicin) originally derived from bacteria, an antibiotic used in cancer treatment can damage cardiac myocytes by interfering oxygen transport inside the cell, (by decreasing in mitochondrial oxidative phasphorylation), by simple words choking heart muscle cells. It is dose related.. ...Read more

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What is the side effect of doxorubicin?

Several effects: Doxorubicin is a powerful medication used in chemotherapy to treat cancer. Like many chemotherapy drugs, it causes side effects including hair loss. The dose has to be managed carefully to avoid damage to the heart. If you have cancer that requires this medication, your doctor will discuss the risks and benefits in more detail. No one is given this medication unless it's really needed. ...Read more

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Anyone had to use doxorubicin as a chemotherapy? Side effects?

Reduce toxicity with: Fortunately I have not had to use it personally but some of my patients have. Doxorubicin can cause nausea, vomiting, low white blood cell count & hair loss, but the most serious side effect is serious heart failure.There is evidence that taking vit c, e, b2, coq10, carnitine and melatonin can protect against cardiotoxicity while enhancing effectiveness! I strongly advise taking these. See comment:. ...Read more

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Has anyone had any experiance using cisplatin or doxorubicin for osteosarcoma?

Has anyone had any experiance using cisplatin or doxorubicin for osteosarcoma?

I shall try: Both drugs are being used in osteosarcoma. Each has its own benefits and side effects. It is a balance beween benefits and risks. Drug combinations areusually used. Age and order of use (1st-round or 2nd) are important factors. Protocols based on national standards are routinely followed. Thank yu for asking. Consult with your cancer doctors. ...Read more

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How can vincristine and doxorubicin be fatal to a cell?

They are/Bind to nuc: They bind to nuclear elements and stop dna synthesis which leads to cell death. ...Read more

Dr. Krishna Kumar
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