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Doctor insights on: Down Syndrome Ribbon

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Is Down syndrome inherited?

Is Down syndrome inherited?

Not usually: The only way to inherit down syndrome is if one parent has down syndrome and passes 2 copies of chromosome 21. Few people with ds reproduce, so that is not usually a factor. ...Read more

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Dr. Kathryn Akin
654 doctors shared insights

Down Syndrome (Definition)

A genetic chromosome 21 disorder causing ...Read more


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Is down syndrome sex-linked or autosomal?

Is down syndrome sex-linked or autosomal?

Down Syndrome: Down syndrome, also known as Trisomy 21, is an autosomal genetic disorder. Down syndrome occurs when a person has a full or partial copy of chromosome 21. ...Read more

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Is Down syndrome dominant or recessive?

Neither: Down syndrome happens when an extra 21 chromosome is present in all the cells of the body. It happens before conception when the donor egg fails to shed one of its 21 chromosomes in the formation of the egg & the male 21 joins the female pair & creates an embryo with 3 number 21's. ...Read more

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Down syndrome is autosomal dominat?

Down syndrome is autosomal dominat?

No autosomal: Down syndrome happens when an extra 21 chromosome is present in all the cells of the body. It happens before conception when the donor egg fails to shed one of its 21 chromosomes in the formation of the egg & the male 21 joins the female pair & creates an embryo with 3 number 21's. It has nothing to do with traits or mutations in the gene code. ...Read more

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What is down syndrome?

What is down syndrome?

Chromosome defect: Ds is one of the more common chromosome(c) defects that can survive pregnancy (many others miscarry).Eggs are supposed to have a single 21c & combine with the 21 from dads normal sperm.Here a pair of moms 21c +dad's 21 creates a baby with the extra 21c in all tissues.This extra material confuses the creation of body parts causing ds..Various prenatal tests can pick up signs early on. ...Read more

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Does epicanthal folds always mean down syndrome?

Does epicanthal folds always mean down syndrome?

No: Epicanthal folds can also be seen in asians, russians, and other races/cultures. In down syndrome there are other features such as hypotonia, wide space between 1st and 2nd toe. There is a 50% chance of heart defects as well. The palpebral fissues (the eyelid opening) slants upward. The 5th finger is often short and curves inward. There are many other features with down syndrome. ...Read more

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Is down syndrome autosomal or sex linked?

Is down syndrome autosomal or sex linked?

None of the above: Down syndrome happens when an extra 21 chromosome is present in all the cells of the body. It happens before conception when the donor egg fails to shed one of its 21 chromosomes in the formation of the egg; the male 21 joins the female pair & creates an embryo with 3 number 21's. It has nothing to do with traits or mutations in the gene code. ...Read more

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Help docs, is goldenhar syndrome alike to down syndrome?

No: Down's Syndrome is caused by a translocation of the 21st chromosome. The cause of Goldenhar syndrome is not exactly clear. Totally unrelated syndromes. ...Read more

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Does epicanthal folds mean down syndrome?

Epicanthal genetics: An epicanthal fold by itself does not mean that you have down's syndrome. ...Read more

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Is Down syndrome sex linked/recessive/or dominant?

Is Down syndrome sex linked/recessive/or dominant?

None of the above: Down syndrome happens when an extra 21 chromosome is present in all the cells of the body. It happens before conception when the donor egg fails to shed one of its 21 chromosomes in the formation of the egg; the male 21 joins the female pair & creates an embryo with 3 number 21's. It has nothing to do with traits or mutations in the gene code. ...Read more

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What are the phenotypes for fragile-x syndrome and down syndrome?

What are the phenotypes for fragile-x syndrome and down syndrome?

Fragile x syndrome: Fragile x syndrome is x linked dominant condition.It does not follow usual pattern of inheritance for x linked male carriers pass their premutations to all their daughters.Male cwith full mutation can pass premutation to all their daughters. The females with full mutation are able to pass full mutation on, so therotically there is 50% chance that a child will be affected.Iam sorry but it is littl. ...Read more

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What are the differences between fragile x syndrome and down syndrome?

Different chromosome: Fragile x is a condition created when an abnormality in a faulty x chromosome is allowed to interfere with the cells in the body. In females, their other x prevents most problems while males with a y cannot block the abnormality. Down syndrome has a whole or extra piece of a 21 chromosome in every cell which interferes with normal cell function. ...Read more

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What's the relationship between trisomy 21 and down syndrome?

What's the relationship between trisomy 21 and down syndrome?

Name game: Dr.Langdon Down worked at a home for the retarded in Britain in the 1800's.He was credited for the first published description of the syndrome that would carry his name. After the human chromosomes were identified and numbered in the 1950's, DS was studied and trisomy 21 was identified in most. Later studies show an extra piece of a specific area of the 21 is all that is needed to have DS. ...Read more

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Large abdomen in utero sign of down syndrome?

Large abdomen in utero sign of down syndrome?

Unlikely: Thick umbilical cord or short thigh length with positive quad screening is often noted in fetus with down syndrome. ...Read more

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Is Down Syndrome a sex linked chromosomal disease?

Is Down Syndrome a sex linked chromosomal disease?

No: Down syndrome is an abnormality of chromosome numbers, not a mutation on a sex chromosome. During conception only one of chromosome of each pair is given by both parents to the fertile egg.If a parent adds their 2 # 21 chm to the other parents # 21, 3 end up in the egg ; the excess 21 causes the all the problems.Rare forms are causes by a extra piece of a 21, but that's another issue. ...Read more

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What is the difference between Angelman syndrome and Down syndrome?

Neurodevelopmental : Disorders like AS & DS that cause Intellectual Disability differ in etiology, signs & symptoms & Neurobehavioral profiles including motor, language, cognitive & social/ adaptive skills. The genetic accident that causes DS gives a fetus 3 copies of Chromosome 21; a fetus with AS may lack a maternal UBE3A gene, have 2 copies of the gene from dad, or only dad's gene is active at Chr.15 q11.2-q13. ...Read more

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Is irritable bowel syndrome and inflammatory bowel disease the same?

Is irritable bowel syndrome and inflammatory bowel disease the same?

Not even close!: Inflammatory bowel disease (see my earlier healthtap answer) is a systemic inflammation of the gut. Irritable bowel syndrome is a symptom complex without inflammation. Symptoms for both may be similar/ recurrent. The term "colitis" (=colon inflammation) is often erroneously applied to ibs patients. Ibd patients can have ibs, & ibs patients can develop ibd but the two are etiologically unrelated. ...Read more

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Babys in womb with Down syndrome have short limbs?

Babys in womb with Down syndrome have short limbs?

Yes.: Checking limb length on ultrasound can be one of the ways to screen for downs syndrome. ...Read more