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Doctor insights on: Down Syndrome Dominant Or Recessive

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Dr. James Ferguson
Board Certified, Pediatrics
40 years in practice
144M people helped
1

1
Is Down syndrome dominant or recessive?

Is Down syndrome dominant or recessive?

Neither: Down syndrome happens when an extra 21 chromosome is present in all the cells of the body. It happens before conception when the donor egg fails to shed one of its 21 chromosomes in the formation of the egg & the male 21 joins the female pair & creates an embryo with 3 number 21's. ...Read more

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Dr. William Forsythe
Board Certified
21 years in practice
169K people helped
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Dr. Kathryn Akin
631 doctors shared insights

Down Syndrome (Definition)

Down syndrome is a genetic condition in which there is an extra chromosome present. Symptoms may range from mild to severe. Children with Down syndrome share a common physical appearance including a flattened nose, small ears, a small mouth, upward slanting eyes, and a single crease in the ...Read more


Dr. James Ferguson
Board Certified, Pediatrics
40 years in practice
144M people helped
2

2
I was wondering is Down syndrome dominant or recessive?

I was wondering is Down syndrome dominant or recessive?

No autosomal: Down syndrome happens when an extra 21 chromosome is present in all the cells of the body. It happens before conception when the donor egg fails to shed one of its 21 chromosomes in the formation of the egg ; the male 21 joins the female pair ; creates an embryo with 3 number 21's. It has nothing to do with traits or mutations in the gene code. ...Read more

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Dr. William Forsythe
Board Certified
21 years in practice
169K people helped
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Dr. William Singer
Board Certified, Pediatric Neurology
45 years in practice
5M people helped
3

3
Is it true that Down syndrome is dominant or recessive?

Is it true that Down syndrome is dominant or recessive?

Neither: Down syndrome is neither dominant nor recessive. Down syndrome occurs due to there being 3 number 21. ...Read more

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Dr. Lynne Weixel
Board Certified, Clinical Psychology
30 years in practice
8M people helped
4

4
I am doing a presentation for my class on down syndrome and I need to know why it isn't dominant or recessive. P.S. I need a simplified answer

I am doing a presentation for my class on down syndrome and I need to know why it isn't dominant or recessive.

P.S. I need a simplified answer

Seek info here: Lots of HT doctors have answered this for others - here's a start. Just dig a bit further, but it's a good reply. Source: HealthTap, https://edc1.healthtap.com/user_questions/22610 ...Read more

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Dr. William Forsythe
Board Certified
21 years in practice
169K people helped
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Dr. James Ferguson
Board Certified, Pediatrics
40 years in practice
144M people helped
5

5
Is Down syndrome an autosomal dominant gene ? Please advise!

Is Down syndrome an autosomal dominant gene ? Please advise!

Not autosomal: Down syndrome happens when an extra 21 chromosome is present in the cells of the body. It happens before conception when the donor egg fails to shed one of its 21 chromosomes in the formation of the egg & the male 21 joins the female pair & creates an embryo with 3 number 21's. It has nothing to do with autosomal traits or mutations in the gene code. ...Read more

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Dr. James Ferguson
Board Certified, Pediatrics
40 years in practice
144M people helped
6

6
Is Down syndrome sex linked/recessive/or dominant?

Is Down syndrome sex linked/recessive/or dominant?

None of the above: Down syndrome happens when an extra 21 chromosome is present in all the cells of the body. It happens before conception when the donor egg fails to shed one of its 21 chromosomes in the formation of the egg; the male 21 joins the female pair & creates an embryo with 3 number 21's. It has nothing to do with traits or mutations in the gene code. ...Read more

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Dr. James Ferguson
Board Certified, Pediatrics
40 years in practice
144M people helped
7

7
Down syndrome is autosomal dominat?

Down syndrome is autosomal dominat?

No autosomal: Down syndrome happens when an extra 21 chromosome is present in all the cells of the body. It happens before conception when the donor egg fails to shed one of its 21 chromosomes in the formation of the egg & the male 21 joins the female pair & creates an embryo with 3 number 21's. It has nothing to do with traits or mutations in the gene code. ...Read more

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Dr. James Ferguson
Board Certified, Pediatrics
40 years in practice
144M people helped
8

8
How can you inherit down syndrome?

Depends on parents: An unaffected mother or father could have a balanced(normal) set of chromasome material where a piece of one 21 chromasome is stuck on another.If the egg or sperm had the normal 21 and an extra 21piece hidden on another chromasome, they could pass it to the baby. It only takes an extra piece of 21 to cause ds.It is important to study ds to verify type, as translocation ds can recur each pregnany. ...Read more

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Dr. Ira Salafsky
Board Certified, Clinical Genetics
50 years in practice
53K people helped
9

9
If someone in your family has down syndrome, is there a larger risk that your baby will have down syndrome?

Slight risk: Most down syndrome is sporadic. A few patients with down syndrome have the extra 21 chromosome translocated on to another chromosome. In some of these cases the parents can carry the translocated chromosome in a balanced form and they and other family members could be at increased risk to have children with the syndrome. ...Read more

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Dr. Alan Patterson
Board Certified, Obstetrics and Gynecology
36 years in practice
72M people helped
10

10
Baby's Down syndrome test results are definite, right?

depends on the test: Depends on what test you had, if you have an integrated screen pr the older AFP blood test it gives you odds of downs like 1 out of some number, the only definite test is an amniocentesis, if you have further ?S you should be talking to your obgyn like i always talk with my patients so they understand everything. ...Read more

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Dr. William Forsythe
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