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Double Stranded Dna Lupus Tests
4/5 results- test neg scl70, double stranded dna, ssa, ssb, smith rmp sederate, esr&crp norm, electrolyte/white/red blood norm.Again + ANA 1:160 centromer. What additional test to exclude scleroderma/crest?
How about it?: Up to a quarter of women your age have an ANA (immunofluorescent antibody) at a low titer like yours with a speckled pattern. If there's a question of whether you have lupus or one of its relatives, it's a piece of information to note and file for future reference. A negative ANA would rule several things out. Your result proves nothing positive. Best wishes. ...Read more
Blood tests showed high antibodies to: ana, ssdna, sm, rnp/sm, ssa(ro), ssb(la), scl-70, centromere. Is this likely lupus or a different automimmune?
Prob false positive: To have all these antibodies to be positive is suggestive of a false positive result. Virus infection can cause similiar findings. Ultimately these results have to be interpretted in the context of your doctor's findings. Talk to your doctor. ...Read moreSee 1 more doctor answer
I'm having negative DNA ,Sm and Rnp antibodies, but positive sm/rnp antibody,and high ANA titre speckled,so what is the diagnosis ?
Lupus: These serologies are rather non specific. The speckled ANA is non specific. In Systemic Lupus Erythematosis (SLE) it is usually homogeneous in its staining. Anti-Sm and Anti RNP can be see in mixed connective-tissue diseases and overlaps with SLE, scleroderma and myositis. As often is the case a specific diagnosis cannot be made. You need to see a Rheumatologist. ...Read more
I have positive ANA sm, ssa (ro), ssb (la) , ro52, jo-1, sci-70, ribosomal p antibodies what are the levels for each antibody that signify lupus ?
Level not important: If these antibodies are truly positive the degree of positivity is not that important. ...Read more
Would bloods for autoimmune screen ANA double stranded DNA ENA anca still show positive if there had been an autoimmune response even 6 years ago?
See below: You also have to take in account that these panels frequently have false positives and assays vary from lab to lab. It is has been estimated that up 30% of all anas drawn are false positives. Only your doctor or your rheumatologist can interpret these results in context with your history and symptoms. ...Read moreSee 1 more doctor answer
ANA positive SSA SSB weekly positive SCL weekly positive RNP SM weekly positive. Any implications? What are the differential diagnosis? WaDoes it mean
Pos auto ab tests: You are describing positive tests for auto antibodies. The differential diagnosis can be extensive. I am assuming a rheumatologist has ordered these tests? You need f/u with them to educate you what they mean, what further tests may need to be done and review your symptoms. Proper rheum DX is not based only on test results, but exam findings and symptoms of patient. Good luck. ...Read moreSee 2 more doctor answers
Ana direct positive ANA , ifa neg , rnp 2.3, CRP 5.4 ss-b2.7.Diag with lupus connective tissue and sjorgen all at once? Why 2 ANA tests different answ
They can change!: Appears you have mctd with sjogren's like features based on the labs and titers. No lupus marker present! ...Read more
I have had (2X's) DNA antibody, double stranded = 200+; also tested (2X's) ANA test = positive; ?
Sle: you most probably have lupus but I would try to go see a specialist make sure. ...Read more
I have positive ANA sm, ssa (ro), ssb (la) , ro52, jo-1, sci-70, ribosomal p antibodies what are the levels for each antibody that signify lupus?
Levels not important: If the antibodies are positive, they are positive. The degree of positivity does not matter. ...Read more
Biopsy DLE Inconclusive Weak Positive ANA,ds-DNA Normal ENA R Positive ANT RNP positive CBC Good (3 clinical)Photosen Rash Ears 250 Hair loss day DLE?
Possibly: The positive RNP can be seen in Mixed Connective Tissue Disease which can be associated with a positive ANA and skin rashes and hair loss. Discoid can be associated with abnormal blood tests also. If discoid lesions on the scalp can cause hair loss. Lupus also still needs to be considered. Protect yourself from the sun and see a rheumatologist ...Read more
May be: Why were these tests done? You must have had some symptoms for your doctor to order these tests. Negative results on blood tests are not an assurance that there is no disease. Please follow your doctor's advice for follow-up care. ...Read more
Sm/rnp antibody- ANA choice- positive, speckled/titer: 1:1280; sm & rnp (done alone) negative; sm/rnp antibody (together?) positive 3.0 guessing mctd?
Heads up: One of the things that's frustrating about these antibody tests looking for different connective tissue diseases is that they are difficult to do and are fraught with pitfalls. I suspect you've had at least one lab error to complicate your workup. Have you have a tube test for u1-rnp? Your clinical symptoms and signs actually tell more about your diagnosis ; best direction for treatment. ...Read more
Ana screen positive, ANA titer 320, rash very often on face, nucleolar pattern. Any significance?
DLE Biopsy Inconclusive Weak Positive ANA, ds-DNA Normal ENA R Positive ANT RNP positive .FBC &Urine Ok Photosen Rash face &Ears fingers consider SLE?
Consider SLE or over: Might consider SLE or overlap syndrome or both. You need to see a rheumatologist ...Read more
Is hiv-1-pcr quantitative and HIV RNA PCR quantitative same tests?can DNA PCR test be quantitative?
(Biopsy DLE Inconclusive)ds-DNA Normal.Weak Positive ANA,ENA R Positive ANT RNP positive FBC &Urine Ok.Photosen,Rash face&Ears blister fingers... SLE?
What would cause a high positive ANA (1:640) speckled, nucleolar with a low positive smooth muscle antibody (1:40) but negative SS-A, SS-B, anti-Smith, RNP, SCL-70, Anti Jo antibodies? Liver disease?
Probably normal: Many people have a positive ANA without being sick. If you also have elevated liver enzymes, a workup for autoimmune hepatitis may be continued, but if there's nothing to suggest a liver problem biochemically, I'd not be in a hurry to diagnose despite anti-smooth-muscle. ANA means nothing apart from the clinical picture. Best wishes. ...Read more
Not enough data: The diagnosis of luppus is made on the basis of clinical signs and symptoms confirmed by specific lab tests including the dna antibody. This antibody can also be positive in other auto immune diseases. Since you did not mention symptoms, there is no way to answer your question. ...Read more
What definitive lab test can r/o or confirm lupus while prego? + hashimotos , also + ana, +double stranded DNA . How do I determine a true yes or no?
See details: First of all, see a rheumatologist if you have not done so already. While an ANA can often be positive in hashimoto's it is much more unusual for the dna to be positive. Since you do not list your symptoms, it is impossible to offer a more specific opinion. ...Read moreSee 1 more doctor answer
Just diagnosed with lupus due to double stranded dna. My ch50 was 350 though. Usually this is low in lupus. What could this mean?
See rheumatologist: Serologic lab results in patients suspected as having lupus can be tricky to interpret. If you have not done so already, see a rheumatologist for a full evaluation. He/she can review your entire picture including the history and physical and can discuss the significance of the various lab tests. ...Read more
Is it possible that a person have lupus and CNS symptoms along with fatigue, pos ANA and double stranded dna? And not the classic symptoms?
I had a positive ana, double stranded dna, and I believe smith's antibodies. I also had a butterfly rash at the time. Besides lupus, what could it be?
Probably Lupus: A butterfly rash is often seen with lupus, but could also been seen with vitamin deficiency disorders like pellagra or connective tissue disases like dermatomyositis. However, the positive ANA and smith's antibodies most likely indicate it is lupus. You should see your physician to be properly diagnosed. ...Read moreSee 1 more doctor answer
How common is it to get a false positive for lupus while pregnant. I also have hashimotos got a + double stranded DNA very high ?
Blood test came back as follows: Anti-Double Stand DNA-14 IU/mL, (CH50 )-63 U/mL. Rheumatologist says it is not Lupus, should I get a second opinion?
More information : Thr rheumatoid diseases are best diagnosed clinically. Go back to your doctor and discuss with him all your symptoms ...Read more
My double stranded DNA is 6 which is "indeterminate" what does "indeterminate" mean when it comes to this test?
hard to say: The results need to be evaluated in the context of the clinical picture. What symptoms led to the test being ordered in the first place? ...Read more
Hello. I have a positive double stranded DNA test result (anti-dna (ds) ab qn of 29 with positive being above 9. Ana is negative, what can this mean?
Abnormal tests: Best to discuss this question with the doctor ordering your tests. ...Read more
Hi there, I have sjögrens syndrome and mild lupus but my double strand DNA was neg, my ANA was 1:640 with speckled pattern. How can it be mild lupus?
Questionable: No one knows what lupus really is, so it's defined in terms of a checklist. A certain total number of findings allows the diagnosis to be made. The real question is, "do we treat, and if so, how?" good luck -- sjogren's alone is quite a challenge, and often runs with lupus or lupus-like illness and gives its own positive ana. ...Read moreSee 1 more doctor answer
ANA1:320 DNA neg CCP neg RF neg. my rheumatologist believes I have RA but testing for lupus due to symptoms but all these blood tests are confusing.. ?
ANA positive: A lot depends upon what is going on. with a person's signs and symptoms and the suspected disorder, ANA testing may be used along with or followed by other autoantibody tests. Lupus is only one thing that may be ANA positive. Others are sjogrens and other autoimmune. Many symptoms overlap/positive ana further testing may be ordered. Speak to your DR Its what rheumatologists know a lot about! ...Read more
Do I have lupus? Ana screen came back as positive/abnormal. Ana titers are 1:320. Dna test came back as normal. My mchc is low and so are my iron stor
SM 5 RNP 9 SSA 14 SSB 7 SCL-70 10 JO-1 7 Histone 3 Centromere 3 CCP 1 ANA 1:320 DNA neg..Do these blood tests indicate lupus?
+ ANA: This may indicate Lupus, you need to f/u with your Rheumatologist to get a complete explanation of all of your results. It looks like you definitely have some kind of autoimmune disorder. Are you having any kind of pain in your joints? What is your RA factor? Let your Dr. know about this. Good Luck ...Read more
Hi, I'm worried about Lupus. Waiting to see specialist. Double Strand DNA is 5, noted as indeterminate. ANA is 1:640. And eGFR is 85. Joint pain.
Lupus is possible. : The specialist will be able to help you to see if your symptoms, in combination with that blood test results, would be consistent with lupus. Lupus is a rather nebulous diagnosis, with many nonspecific symptoms in combination. Joint pain alone does not give us that diagnosis, and blood testing is not considered diagnostic but more circumstantial. ...Read more
The only pos blood test I have is ANA of 1:320. Neg RF CCP DNA and SM antibody was low of 10. Extreme joint pain 6 mnth. RA, lupus, or neither?!
+ ANA: There are other spondyloarthropathy that can cause a lot of pain and will require treatment. Did they do an HBLA27 test? Make sure you f/u with your rheumatologist. If you have RA you can get these results. You may need to start a biologic medication. Good luck and feel better soon) ...Read more
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