Doctor insights on:
Dostinex Metabolic Agent
Glimepride or metformin sustained release? Which anti diabetic tablet is safer for stage 2 renal disease (diabetic nephropathy)
Caution: Metformin is contraindicated as renal function declines. Glimepiride is ok, but all such agents are more potent as renal function falls since Insulin is metabolized by the kidney and Insulin levels may persist at a higher level with renal disease. Night time hypoglycemia is more common w/renal disease so monitor carefully. ...Read moreSee 1 more doctor answer
Femara (letrozole) is metabolized in liver by cytochrome p450 system. Astaxanthin says "use cautiously w drugs metabolized by liver's cytochrome p450 enzyme system; does this mean don't use astaxanthin w femara (letrozole)?
Not necesarilly but: Virtually all drugs are metabolized by cytochrome p450 enzymes.Astaxanthin can stimulate these, so it could lead to lower blood levels of "certain drugs" according to http://www.Naturalmedicinejournal.Com/article_content.Asp?Article=293. I no of no evidence that Femara (letrozole) is one of the drugs it interacts with. Small amounts of astaxanthin are unlikely to have much effect.Ask the doc who prescribed it. ...Read moreSee 1 more doctor answer
Maybe-fiber-fuller!: Pgx or polyglcoplex is a one-of-a-kind complex of water-soluble polysaccharides or plant fibers developed using a patented technology. It is marketed as a weight loss and regular dietary supplement that fosters healthy blood sugar levels, curbs hunger, and minimizes unwanted weight gain. T is recommended to take some pgx before every meal with at list 8 ounces of water per 2.5 gram serving. ...Read moreSee 2 more doctor answers
Does dopamite(dopamine supplement) increase more dopamine level or prescribed medicine like biperiden(dopamine reuptake inhibitor) does?
NO: I am not aware of any connection. ...Read more
25y/o male being treated for prolactinoma. Does using nicotine/tobacco products increase prolactin blood levels? Or counter act cabergoline? Thanks!
Metab syndrome: An insulin-sensitizing agent, such as metformin, is often used as hyperglycemia treatment in patients with metabolic syndrome. Literature suggests that metformin may help to reverse the pathophysiologic changes of metabolic syndrome. Cannot find any evidence that Rifampin is a risk factor for metabolic syndrome. ...Read more
Hydroxyprogesterone hexanoate is androgen precursor with elimination half-life 7.8 d,for an injection 5ml of 250 mg/mL what is such androgenic effect?
A Hairy Proposition: In women, excess amounts of androgens can cause such "virilizing" effects as acne, hirsutism (excess hair growth in "inappropriate" places, like the chin or upper lip) and thinning hair. Long-time use is associated with serious health consequences, such as insulin resistance and diabetes, high cholesterol, high blood pressure and heart disease. It all sounds like lots of fun, doesn't it? ...Read more
Azd 6244- mek inhibitor- a selective mitogen-activated protein kinase (mek) inhibitor. Mk 2206- akt inhibitor. Why prescription for me? It ? Nsclc/mets
Molecular targeting: These agents are designed to selectively knock out key pathways your tumor may use to grow. Presumably you already had your tumor tested for these different mutations. Ask the doctor offering these options to explain their rationale. These are investigational studies and many of the treatment costs may be covered-ask. ...Read more
How likely that minocycline 100 mg BID (1- 2015) & clindamycin cause elevated liver enzymes in hepatic function panel (7)&comp metabolic panel,past IV?
Not definite: no specific meds for glutamate dysfunction, anything available has a lot of side effects. ...Read more
How does metabolic acidosis affect liver clearance of drugs? I.E. Should i stop my medications during metabolic acidosis
No: Metformin is not known to be toxic to the kidneys. The concern may be when a patient has naturally kidney function and they take metformin. That person may then be at (rare, but still documented) risk of a condition called lactic acidosis - a potentially dangerous, body-wide build-up of lactic acid that interferes with the delivery with oxygen. ...Read moreSee 1 more doctor answer
See below: Us department of veterans affairs has studied this issue and recognized a number of disorders to be associated with agent orange exposure as detalied in the site below. http://www.publichealth.va.gov/exposures/agentorange/diseases.asp if you have any signs or symptoms pertinent to these disorders you should consut your doctor. If you are a veteran, seek care at a va facility. ...Read more
Can methylphenidate causehigh lvls catecholamines fractionated blod test?+mking result undifferentiat so hyperadrnrgcpots cannot be diagnosis b/c of med use?
Ritalin (methylphenidate) and POTS: Methylphenidate shows up as methampetamine in a blood test. To DX hyperadrenergic postural orthostatic tachycardia syndrome (pots) would be a clinical issue not primarily based on a blood test. I can see trying methylphenidate for the chronic fatigue aspects of pots, but the best treatment is often regular aerobic exercise. ...Read more
Yes: While very uncommon, all of the statin drugs have been known to cause muscle injury. The release from injured muscle of a substance called myoglobin can plug up the kidneys and cause the creatinine to rise. However, under those circumstances there is usually significant muscle pain or weakness and often the urine has a reddish appearance. Also a muscle enzyme (CPK) will be strikingly elevated. ...Read more
Basal glucose =81 mg/dl but insuline =38 mU/ml (insuline/glucose > 0,3 ). Symptoms of ipoglycemia... How to exclude an insulinoma? Ultrasound?thanks!
Hypoglycemia: To diagnose insulinoma, you need to demonstrate inappropriately high insulin/C-peptide when your glucose is low. A glu of 81 is not low, it is normal. You have symptoms of hypo, but these symptoms are often from something else. Insulinoma is rare. Do not start getting CT/ultrasound etc until you establish the biochemical diagnosis first. An Endocrinologist can help you. ...Read more
Ketamine Does..: Conversion of tyrosine to Dopamine is initiated (in part) by tyrosine hydroxylase (th). Long-term abuse of ketamine has been shown to cause "up regulation" and, therefore, increased production of, th as the reason for "delayed but persistent" increase in the neurotransmitter dopamine, a possible reason for "altered mental status" in those who abuse ketamine....Hmmm not sure about flumazenil! ...Read more
Which is a safer, lower side effect profile drug, topamax (topiramate) or oxcarbazapine (in general terms, obv individuals vary)?
Don't 2nd guess: Neither is w/o risk and they are Rx'd for different (w/ overlap) conditions. You need to work w/ your Dr on selecting the best for you - say clearly that safety is impt to you. Know what they expect it to for your condition. Side EFX are pretty similar for both - your other health issues might be the swing vote. ...Read more
Very unlikely: Hi. Your gender is not stated. I've been prescribing cabergoline (Dostinex) for a long time for hyperprolactinemia, and acne's not one of the side effects I see. If you're a man, you might also be being treated with testosterone for the hypogonadism caused by high prolactin, in which case it would be the testosterone causing the acne, not the Dostinex (if you're a woman, disregard that statement). ...Read more
Yes: Dostinex (cabergoline) lowers prolactin levels. High prolactin levels can inhibit orgasms. Therefore, Dostinex (cabergoline) can be used to make it easier (or possible) to have an orgasm. Prolactin levels increase each time you have an orgasm. That is why it is hard for men to have orgasms if they have a lot of orgasms. ...Read more
Severe reaction:: If experience one of these severe allergic reactions, please seek immediate care from your medical practitioner. Cabergoline allergies can consist of rash, hives, swelling of lips or mouth, chest pain, shortness of breath, mood changes such as depression, vision changes, behaviour changes (eg aggression). An allergy can also occur if you are allergic to one of the ingredients, eg ergotamine. ...Read more
Trick question?: Hi. Let's assume you had galactorrhea & amenorrhea (hyperprolactinemia syndrome). You go on cabergoline. The breast milk stops and periods start back up. Are the periods coming once a month with normal flow? You know the answer to that, not us docs out here in internet-land. Good luck! ...Read moreSee 1 more doctor answer
I have taken dostinex to stop my supply of breastmilk after 3 months. can i express a bit for relief? how long does the process take?
Do what you must: The medication is seldom offered in the US to stop breastfeeding. Simply using the baby to soften your engorgement for a few <3 min/side and completing feeds with a formula will do the job by signaling your body to quit making the volume. Any feeding will prolong the weaning process but you must do what works for you. It takes whatever time it takes. ...Read more
My obgyn prescribe me dostinex (cabergoline). 25mg twice a week. I would like to know, why i can't take it daily or maybe more times a week?
See below: Under your doctor's supervision.Get a more detailed answer ›
Dostinex (cabergoline): Some common side effects of Dostinex (cabergoline) are: nausea, headache, dizziness, constipation, low blood pressure, dry mouth, bowel changes (either constipation or diarrhea), abdominal pain... For more information, see link below. http://www.drugs.com/pro/dostinex.html. ...Read more