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Doctor insights on: Dose Dense Taxol

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Is neulasta (pegfilgrastim) needed with weekly taxol?

Is neulasta (pegfilgrastim) needed with weekly taxol?

No!: Neulasta (pegfilgrastim) is a long-acting injection that increases your white blood cells. It should only be given during a two or three week window when you're not receiving chemotherapy. If you're receiving Taxol every week, you should not receive neulasta (pegfilgrastim). If you do, the Taxol can kill the dividing white blood cells, and harm your bone marrow stem cells. It is not fda-approved to give during weekly chemo! ...Read more

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Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Estrogen receptor ER positive breast cancer adjuvant Taxol (paclitaxel) benefits?

Get Oncotype: In order to answer this question, more details are needed (size of tumor, lymph node involvement, etc). A test that will help to decide if you need chemotherapy or not is the oncotype dx. I highly recommend you speak with your oncologist and even consider a 2nd opinion. ...Read more

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Neulasta (pegfilgrastim) with weekly taxol, is this okay?

Neulasta (pegfilgrastim) with weekly taxol, is this okay?

No!: Neulasta (pegfilgrastim) is a long-acting injection that increases your white blood cells. It should only be given during a two or three week window when you're not receiving chemotherapy. If you're receiving Taxol every week, you should not receive neulasta (pegfilgrastim). If you do, the Taxol can kill the dividing white blood cells, and harm your bone marrow stem cells. It is not fda-approved to give during weekly chemo! ...Read more

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Adding more chemo dasatinib and carboplatin likely to work?

Adding more chemo dasatinib and carboplatin likely to work?

Restate question: Hi jsalyers9. Can you restate your question with a little more information. What is being treated? What treatments have already occurred? Thanks. ...Read more

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Is Abraxane or Taxol (paclitaxel) better for neuropathy?

Is Abraxane or Taxol (paclitaxel) better for neuropathy?

Not really: Abraxane is a derivative of Taxol. It is employed after recurrent or metastatic pancreas cancers have failed Gemzar (gemcitabine) adding about 8 wks to the overall survival in these patients. The drug,protein-bound paclitaxel is an injectable formulation of paclitaxel, It has almost the same extent of neuropathy. ...Read more

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After taxol (paclitaxel) reaction for 3b squamous nsclc, husband is on weekly treatment, 2 wks abraxane, then 1 w/ abraxane/carboplatin. Is it normal & effective?

Yes its a good alter: If your husband has allergy to Taxol, (paclitaxel) then using Abraxane as an alternative is a good decision. This treatment works well in about half (50%) of the patients, not in the others. You will know within 6 to 8 weeks of chemotherapy treatments. ...Read more

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Clomid (clomiphene) dosage for low t?

Clomid (clomiphene) dosage for low t?

"Low T": Is not a disease or even a well-defined syndrome. Therefore there is no clear treatment. Clomid (clomiphene) is one speculative treatment, but there is not a "correct" dose. ...Read more

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Ciii ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin. In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?

Ciii  ovarian cancer in 06, 1212, surgery and chemo paxitaxtel/carboplatin.  In remission. Recurrence treated with tamoxifen, carboplatin alone, abraxan, then topotacan to no avail. Which chemo next?

Many options: Choosing chemo depends on many factors, so only your doctor can decide what might work for you. Drugs you haven't mentioned include altretamine, capecitabine, cytoxan, (cyclophosphamide) vinorelbine, ifosfamide, etoposide, and irinotecan. There are also several hormonal agents. And a clinical trial might be an option. Check out www.Cancer.Gov for more info. And good luck. ...Read more

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Enbrel (etanercept) 50 mg sq x 3 months for RA + psoriasis. Very little improvement. Any downside to increasing to enbrel (etanercept) 50 mg sq twice weekly? Mtx not tolerated.

Enbrel (etanercept) 50 mg sq x 3 months for RA + psoriasis. Very little improvement. Any downside to increasing to enbrel (etanercept) 50 mg sq twice weekly? Mtx not tolerated.

No real downside: Tnf inhibitors like Enbrel don't increase in toxicity like other meds do. Increasing the dose to 50mg twice weekly is a good idea.But, if you don't also take methotrexate, for any reason, you will be more likely to develop antibodies against the Enbrel and neutralize it--causing it to lose most or all effectiveness.If increasing Enbrel does not work, consider another med like Humira or remicade (infliximab). ...Read more

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Equivalent dose of perphenazine 8mg tid to haloperidol.Because of somnolence &weight gain.

Equivalent dose of   perphenazine 8mg tid to haloperidol.Because of somnolence &weight gain.

Ask pharmacist: An answer to a question like this is likely not going to be precise since your physician will want to take many things into consideration before making such a switch. It would be best to have the pharmacist contact the physician in order to carry out this particular substitution of drugs. ...Read more

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Is herceptin (trastuzumab) effective in treating bowel cancer?

Is herceptin (trastuzumab) effective in treating bowel cancer?

No: There is no evidence that Herceptin (trastuzumab) is useful in treating colon cancer. It' s use has been expanded to patients with metastatic esophageal and stomach cancers who over express the her2 protein ...Read more

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At which dose risperidone cause wieght gain I'm taking 1 mg risperidone?

At which dose risperidone cause wieght gain I'm taking 1 mg risperidone?

Monitor your weight: There is no way to predict what exact dose will have a particular side, eg, weight gain, with Risperidal (risperidone). You may have no weight gain. Best to keep track of your weight. If you've gained 5+ lb and can't explain why, discuss with prescribing doctor. Dose may be adjusted or alternative med considered. Eating healthy and regular exercise are also important to control weight. I hope this helps. ...Read more

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What is the difference between 21 dayys cycle &dosage dense regim in carboplatin/taxol?

Chemo: Dose-dense chemo given every 14 days instead 21. You should discuss with the doctor the reasons for offering it, could be a few. ...Read more

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Who should avoid taking taxol (paclitaxel)?

Who should avoid taking taxol (paclitaxel)?

Discontinued: Taxol (paclitaxel) has been discontinued in the us. There was originally concern because of the environmental impact of its original sourcing, no longer used, from the pacific yew. In addition, the assignment of rights, and even the name itself, to bristol-myers squibb were the subject of public debate and congressional hearings. ...Read more

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Is the chemo drug, docetaxel (taxotere) a carboplatin based duplex ?

Is the chemo drug, docetaxel (taxotere) a carboplatin based duplex ?

YES DOUBLET: Taxotere (docetaxel) + carboplatin: is a combination regimen used in certain cancers like lung, ovary and breast (with herceptin). ...Read more

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How is chemo drug - docetaxel (taxotere)?

How is chemo drug - docetaxel (taxotere)?

?: Sorry but your question makes no sense. What do you want to know about docetaxel? ...Read more