Doctor insights on:
Dornase Alfa Medication
Thinning mucus: Dornase alfa, called "pulmozyme", breaks down dna which is part of the material in thck chest mucus in patients with chronic lung disease such as cystic fibrosis. The medicine thins the mucus and makes it easier to cough out. It is used every day for months or years and gets into the lungs by inhaling the medicine in a mist. Treatments take 10-20 minutes. It's not used for colds or bronchitis. ...Read more
In the refrigerator: There should be specific instructions when you get a new prescription as to where to store it (what temperature and for how long), and whether light damages it. There should also be an expiration date to tell you when it will no longer work if you keep it too long. Don't use it afterthat date. If you have questions, ask your pharmacist or go to the website shown in the package insert. ...Read more
Thick chest mucus: Dornase alfa, called pulmozyme, (dornase alfa) is a medicine that makes lung mucus thinner and easier to cough up. It was developed for patients with cystic fibrosis and is used every day for months or years. It is not used for short-term colds or bronchitis. It gets into the lungs by breathing in a mist of the medicine from a nebulizer machine. Treatments usually take 10-20 minutes. ...Read more
My sister makes herself throw up when she does her pulmozyme (dornase alfa). What can I do to help her?
Mgt/CF: Some secretions can be swallowed and this can cause irritation of the stomach lining. She should speak with her PCP about the use of an antacid, following the Pulmozyme (dornase alfa) with nebulized saline to clear the secretions. Chest physiotherapy is an important part of her management. Does she wear a vest for CPT? A virtual consultation to review chest clearance and her medications can be booked online. ...Read more
Could pulmozyme (dornase alfa) use result in increased respiratory rate in non-cf patient with a tracheostomy?
Maybe: Side effects with Pulmozyme (dornase alfa) are various and can include irritation of the throat, nose and voice changes. It can also cause hoarseness. I use a fair amount in my patients and have not seen it increase respiratory rate. I guess if it was irritating the airway you could breathe faster due to pain/discomfort. I don't think that increased resp rate is very common on this drug. ...Read more
See Below: I'm confused. If this is a patient, you need to discuss this with the patient's doctor. ...Read more
Do menopur and gonal f (follitropin alfa) medication help more follicle appear or just help follicles grow to a mature size?
I'm starting a second IUI cycle. I have ~325 units left in an unexpired Gonal F (follitropin alfa) pen. Is it as effective to use the remainder of that medication?
Probably: If it has been properly refrigerated and is unexpired you should be alright ...Read more
Not sure about less?: If you are taking drugs for a chronic condition like heart disease, diabetes, hypertension, then this a difficult question. If you are concerned about how many pills you are taking in a day, maybe combinations or long acting drugs can reduce the number. Either way, this is to be discussed with your physician since these alternatives are not for everyone. Good luck. ...Read more
Otc: Nonsteroidal anti-inflammatory drugs (NSAIDS) can help with both pain relief and in reducing inflammation. Examples are ibuprofen (like Advil, Nuprin or Motrin), Naproxen sodium (like Aleve, (naproxen) Naprosyn, Anaprox) or Asprin (such as Bayer, Ecotrin, Ascriptin). Avoid NSAID's if pregnant or allergic to them. In that situation can consider acetaminophen. ...Read more
Dose??: If you mean is the dose too high we must narrow it down to what type of medication. All medications have side effects- many of which are associated with excessive dosing. Speak to your primary physician or pharmacist about the specific medication. ...Read more
No: Not every medication makes people darker. Drug-induced skin pigmentation is however often seen. Pigmentation may be induced by many drugs. The primary drugs implicated include antipsychotic drugs, non-steroidal anti-inflammatory drugs (NSAIDs), phenytoin, antimalarials, amiodarone, cytotoxic drugs, tetracyclines, and heavy metals. ...Read more
That is a very: Patient specific question and will have to addressed by your cardiologist. It will depend on whether you had just angioplasty, or also a stent. If stent what type. And your other health issues. Talk to your doc. ...Read more
What is Diagnosis?: When you have a clear diagnosis there are always options for rx. Physical therapy, modalities, otc meds and then rx meds may all be utilized along with complementary rx such as acupuncture, chiropractic and massage. For nerve injury/failed back surgery, treatments such as spinal cord stimulation enable enhanced quality of life and reduced or elimination of opioid medications. ...Read more