Doctor insights on:
Dornase Alfa Medication
Thinning mucus: Dornase alfa, called "pulmozyme", breaks down dna which is part of the material in thck chest mucus in patients with chronic lung disease such as cystic fibrosis. The medicine thins the mucus and makes it easier to cough out. It is used every day for months or years and gets into the lungs by inhaling the medicine in a mist. Treatments take 10-20 minutes. It's not used for colds or bronchitis. ...Read more
In the refrigerator: There should be specific instructions when you get a new prescription as to where to store it (what temperature and for how long), and whether light damages it. There should also be an expiration date to tell you when it will no longer work if you keep it too long. Don't use it afterthat date. If you have questions, ask your pharmacist or go to the web site shown in the package insert. ...Read more
Thick chest mucus: Dornase alfa, called pulmozyme, (dornase alfa) is a medicine that makes lung mucus thinner and easier to cough up. It was developed for patients with cystic fibrosis and is used every day for months or years. It is not used for short-term colds or bronchitis. It gets into the lungs by breathing in a mist of the medicine from a nebulizer machine. Treatments usually take 10-20 minutes. ...Read more
My sister makes herself throw up when she does her pulmozyme (dornase alfa). What can I do to help her?
Mgt/CF: Some secretions can be swallowed and this can cause irritation of the stomach lining. She should speak with her PCP about the use of an antacid, following the Pulmozyme (dornase alfa) with nebulized saline to clear the secretions. Chest physiotherapy is an important part of her management. Does she wear a vest for CPT? A virtual consultation to review chest clearance and her medications can be booked online. ...Read more
Could pulmozyme (dornase alfa) use result in increased respiratory rate in non-cf patient with a tracheostomy?
Maybe: Side effects with Pulmozyme (dornase alfa) are various and can include irritation of the throat, nose and voice changes. It can also cause hoarseness. I use a fair amount in my patients and have not seen it increase respiratory rate. I guess if it was irritating the airway you could breath faster due to pain/discomfort. I don't think that increased resp rate is very common on this drug. ...Read moreSee 1 more doctor answer
See Below: I'm confused. If this is a patient, you need to discussing this with the patient's doctor. ...Read more
Do menopur and gonal f (follitropin alfa) medication help more follicle appear or just help follicles grow to a mature size?
I'm starting a second IUI cycle. I have ~325 units left in an unexpired Gonal F (follitropin alfa) pen. Is it as effective to use the remainder of that medication?
Probably: If it has been properly refrigerated and is unexpired you should be alright ...Read more
Not sure about less?: If you are taking drugs for a chronic condition like heart disease, diabetes, hypertension , then this a difficult question. If you are concerned about how many pills you are taking in a day, maybe combinations or long acting drugs can reduce the number. Either way, this is to be discussed with your physician since these alternatives are not for everyone. Good luck. ...Read more
Yes, but: There are many appetite suppressants on the market but you must be very careful. Do not try any of them without first speaking to your physician. They can often raise your blood pressure which would be a problem with hypertensives.. Ask first before you do anything. Good luck. ...Read more
Otc: Nonsteroidal anti-inflammatory drugs (NSAIDS) can help with both pain relief and in reducing inflammation. Examples are ibuprofen (like Advil, Nuprin or Motrin), Naproxen sodium (like Aleve, (naproxen) Naprosyn, Anaprox) or Asprin (such as Bayer, Ecotrin, Ascriptin). Avoid NSAID's if pregnant or allergic to them. In that situation can consider acetaminophen. ...Read more
Dose??: If you mean is the dose too high we must narrow it down to what type of medication. All medications have side effects- many of which are associated with excessive dosing. Speak to your primary physician or pharmacist about the specific medication. ...Read more
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