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Doctor insights on: Dornase Alfa Allergy In Children

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Do you have idea about dornase alfa uses?

Do you have idea about dornase alfa uses?

Thick chest mucus: Dornase alfa, called pulmozyme, (dornase alfa) is a medicine that makes lung mucus thinner and easier to cough up. It was developed for patients with cystic fibrosis and is used every day for months or years. It is not used for short-term colds or bronchitis. It gets into the lungs by breathing in a mist of the medicine from a nebulizer machine. Treatments usually take 10-20 minutes. ...Read more

Dr. John Chiu
2,638 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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My sister makes herself throw up when she does her pulmozyme (dornase alfa). What can I do to help her?

My sister makes herself throw up when she does her pulmozyme (dornase alfa). What can I do to help her?

Mgt/CF: Some secretions can be swallowed and this can cause irritation of the stomach lining. She should speak with her PCP about the use of an antacid, following the Pulmozyme (dornase alfa) with nebulized saline to clear the secretions. Chest physiotherapy is an important part of her management. Does she wear a vest for CPT? A virtual consultation to review chest clearance and her medications can be booked online. ...Read more

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Where should dornase alfa be stored?

Where should dornase alfa be stored?

In the refrigerator: There should be specific instructions when you get a new prescription as to where to store it (what temperature and for how long), and whether light damages it. There should also be an expiration date to tell you when it will no longer work if you keep it too long. Don't use it afterthat date. If you have questions, ask your pharmacist or go to the web site shown in the package insert. ...Read more

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How is dornase alfa helpful?

Thinning mucus: Dornase alfa, called "pulmozyme", breaks down dna which is part of the material in thck chest mucus in patients with chronic lung disease such as cystic fibrosis. The medicine thins the mucus and makes it easier to cough out. It is used every day for months or years and gets into the lungs by inhaling the medicine in a mist. Treatments take 10-20 minutes. It's not used for colds or bronchitis. ...Read more

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Could pulmozyme (dornase alfa) use result in increased respiratory rate in non-cf patient with a tracheostomy?

Could pulmozyme (dornase alfa) use result in increased respiratory rate in non-cf patient with a tracheostomy?

Maybe: Side effects with Pulmozyme (dornase alfa) are various and can include irritation of the throat, nose and voice changes. It can also cause hoarseness. I use a fair amount in my patients and have not seen it increase respiratory rate. I guess if it was irritating the airway you could breath faster due to pain/discomfort. I don't think that increased resp rate is very common on this drug. ...Read more

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Is it safe to take pulmozyme (dornase alfa) while pregnant or breastfeeding?

Is it safe to take pulmozyme (dornase alfa) while pregnant or breastfeeding?

Yes: Pulmozyme (dornase alfa) is a category b, deemed safe in pregnancy. Its safety in lactation is unreported, but should have minimal absorption, and I would consider the benefits vs risk for lactation on a case-by-case basis with my patients. ...Read more

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Do children grow out of allergies?

Do children grow out of allergies?

Yes: Not all of the food allergies are created equal. Food allergies like dairy, egg, wheat tend to be outgrown. Tree nut and peanut are less likely (although recent studies suggest that 20-30% outgrow the peanut allergy). Environmental allergies tend to "grow on you" with time. Note: the allergy test may remain positive despite the child having outgrown the allergy. Consult with an allergist. ...Read more

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How are children tested for allergies these days?

How are children tested for allergies these days?

Allergy testing: Usually encompasses skin and/or serum (blood) test which are consistent with the child's clinical history. ...Read more

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How often should children be tested for allergies?

How often should children be tested for allergies?

It depends: It really depends on the age of the child, and whether you're talking about food or environmental allergies. I generally will skin test children over age 2 for environmental allergies, while many younger kids need food testing. In terms of frequency, children with environmental allergies may benefit from repeat testing after 2 years, as their allergies can change as they get older. ...Read more

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How do you confirm children's allergies from? Different foods?

How do you confirm children's allergies from? Different foods?

Skin testing: The easiest way to determine whether or not a child is allergic to certain foods is skin testing. Blood testing might also be considered. The gold standard (best) test for food allergy is an oral food challenge (should be done under supervision of a qualified allergist). ...Read more

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Does a cough come with allergies in children?

Does a cough come with allergies in children?

Sometimes: But not all the time. Nasal allergies are not a frequent cause of a really bad persistent cough. In a child with allergies and a really bad cough (assuming no fever) I would be concerned about a reactive airway/asthma type condition. If the child also had eczema I would be even more concerned. ...Read more

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How can I prevent my children from getting allergies?

Breastfeed!: Breastfeeding is shown to be protective for children with a strong family history of allergies. If unable to breast feed, try a hypoallergenic formula such as "nutramigen" or "alimentum". Try to avoid introducing baby foods until 4-6 months of age; once you do, introduce them slowly. Interestingly, exposure to dogs & cats appears to reduce the risk of becoming allergic to those household pets! ...Read more

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What are common signs of allergies towards animals in young children?

What are common signs of allergies towards animals in young children?

Nasal, eye, skin: Children will exhibit sneezing, itchy nose/eye, stuffy nose or cough with close exposures with pets. If licked by a cat or dog and allergy is present, a rash could develop at that site. The allergies could manifest as asthma with cough, wheezing or difficulty breathing. Typically a pattern will be seen, but if it is an indoor pet, the symptoms may be continuous. ...Read more

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Is an h2 histamine blocker ok for children for allergies.?

Is an h2 histamine blocker ok for children for allergies.?

Doesn't help much: H2 histamine blocking drugs are safe for children with allergies to take, but they are of limited value in treating allergies. ...Read more

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Can a parents' allergies to various foods be passed on to their children?

Can a parents' allergies to various foods be passed on to their children?

No: The condition of being allergic is certainly an inherited property. Often, that tendancy is greater in children whose biological mother has allergies. However, specific allergy is generally not thought to be inherited. That is, a parent can be allergic to food, and their children allergic to pollen or insect stings. ...Read more

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Chronic cough in children associated with Flonase allergy?

Chronic cough in children associated with Flonase allergy?

Doubtful: I don't think a child would be allergic to the nasal steroid spray flonase. There are certainly children whose cough may not respond to treatment with flonase, but the reason is most likely a mis-diagnosis rather than an allergy to it. One needs to think about an infectious cause, asthma or possibly reflux to name a few reasons for lack of response to flonase. ...Read more

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How is chronic urticaria of children resolved? With allergy testing?

See below: Allergy testing may hold an answer. However, with chronic urticaria, less than 5% of the time is a cause found. ...Read more

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For children's allergies should you combine zyrtec and claritin (loratadine)?

For children's allergies should you combine zyrtec and claritin (loratadine)?

Pick one: While both zyrtec (cetirizine) and Claritin (loratadine) are approved for treatment of allergies in children, it is rarely necessary to use both at the same time. In my experience, Claritin works for many and zyrtec works for most patients. While there is little harm to combining these, it doesn't add to the effectiveness. ...Read more

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Is it possible that I give my two-year-old children's Benadryl (diphenhydramine) for seasonal allergies?

Is it possible that I give my two-year-old children's Benadryl (diphenhydramine) for seasonal allergies?

Yes: Yes, you can give your 2 year old child Benadryl (diphenhydramine) for allergy symptoms. Its onset is fast within 15-60 minutes and it lasts for about 4-6 hours. Otc zyrtec's onset is also fast and it lasts for 24 hours. Keep in mind that those medications can control mild allergy symptoms. If your child still suffers from the disease after taking otc meds, you might want to bring him or her to see an allergist. ...Read more

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Took 2tsp of children's Benadryl (diphenhydramine) for my allergies, but forgot that I had 3 glasses of 5% dessert wine 3 hours earlier. Should I worry?

Took 2tsp of children's Benadryl (diphenhydramine) for my allergies, but forgot that I had 3 glasses of 5% dessert wine 3 hours earlier. Should I worry?

Not necesarily: I wouldn't drive a car or operate tools or machinery for another 6-8 hours, but this exposure would just make someone groggy. The time needed to metabolize the alcohol suggests at least half was gone before the medicine was taken, and the overlap is not worrisome. ...Read more

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My husband and I accidentally gave our 4 yr old son, who weighs 42lbs, a double dose of childrens benadryl (diphenhydramine) for his allergies (chewable tablets 12.5mg)?

My husband and I accidentally gave our 4 yr old son, who weighs 42lbs, a double dose of childrens benadryl (diphenhydramine) for his allergies (chewable tablets 12.5mg)?

?? no numbers??: The only way for me to comment on the dose is if you list what you gave. Two 12.5 mg tabs in a 42 lb kid might make him groggy but shouldn't hurt in the long run. Four tabs would put him to sleep and he'd be out for a few hours. Luckily the med clears the body in 4-8 hours. ...Read more

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Why do some children have allergies?

Why do some children have allergies?

Exposure + Genes: One needs both a genetic component and "exposure" to a said allergen to develop an allergy. There is a growing support over the past 20 years, that growing up in an environment which is "too clean" can also lead to development of allergies down the road. Either way, allergies are on the rise. ...Read more

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How are children tested for allergies?

How are children tested for allergies?

See below: They are tested the same as everyone else. They can have skin testing performed by an allergist, or blood work ordered by their primary care provider. ...Read more

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I have an allergy to nuts and I was wondering if my children would also be allergic?

Nut allergy: Maybe. Your children may have inherited genes from you that make them more likely to develop an allergy, but they do not inherit a specific allergy to a food e.g. Nuts. The children have to be exposed to food proteins in the diet, before an allergy can develop. Once one develops an allergy then they are always allergic and need proper medical attention to prevent severe problems. ...Read more

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Can children grow out of seasonal allergies?

Can children grow out of seasonal allergies?

Sometimes: Some people's allergies get better over years, some get worse, and some are stable. Keeping allergies well-controlled not only keeps kids feeling better and sleeping better, but also doing better in school (it's hard to learn material when you feel miserable)! also, keeping allergies under control decreases the risk of ear infections and sinusitis. ...Read more

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How are today's allergy tests performed on children?

How are today's allergy tests performed on children?

Skin or Blood: Depending on the clinical history and suspected allergen, some practitioners choose the less painful and timely method, which is a blood test looking for specific ige antibodies, also called rast testing. Percutaneous skin tests are still the gold standard for allergy testing. This is something which you should discuss with your physician. ...Read more

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How do docs test children for indoor & outdoor allergies?

Allergy tests: There are several types of testing. Some involve certain types of blood tests. Another method is to do a series of skin tests done by pricking the skin and applying different allergens. Other tests are provocative tests that can involve challanging the patient with allergic materials. Testing should be done by doctors specializing in allergy to obtain the best results. ...Read more

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What is the cause of environmental allergies in young children?

Air-borne allergies: Environmental allergies affect your respiratory system including the nose, sinuses, eyes and if severe, the lung. Thus, symptoms are nasal congestion, sinus pressure, teary and itchy eyes, cough, wheezing, physical activity limitation and difficulty breathing if you have asthma. ...Read more

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What are symptoms of delayed reaction allergies in young children?

What are symptoms of delayed reaction allergies in young children?

Delayed reaction: Symptoms do not appear for hours or even days. Poison ivy and similar plants cause some of the best-known delayed hypersensitivity reactions. When a person first touches the plant, no reaction occurs for the first 24 to 48 hours.

Read more: http://www. Livestrong. Com/article/253484-types-of-delayed-reaction-allergies/#ixzz2vcsli9lf. ...Read more

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What testing is there for? Children and food allergies?

What testing is there for? Children and food allergies?

Skin & blood tests: Prick testing with allergenic extracts or fresh foods can help confirm allergy, as can blood tests for specific ige antibodies (rast-type tests). However, both types of testing can produce false positive results, and confirmation with food challenges may be needed. ...Read more

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Can a parents allergies be passed on to their children?

Can a parents allergies be passed on to their children?

Not exactly: The ability to react to certain proteins in an allergic way is passed on from parents to their children, but a specific allergy is not. So if a mom is allergic to pollen and the dad is allergic to fire ants, their child may develop allergies but it may be to a food instead. If 1 parent has allergies, the child is 50% likely to develop allergies, but it's a 75% chance if both parents are allergic. ...Read more

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Could food allergies cause irritable children?

Could food allergies cause irritable children?

Yes: Especially in children too young to communicate effectively. Food allergies can manifest as itching, hives, swelling, vomiting and/or diarrhea. Any of these symptoms could lead to being irritable. Similarly, food intolerance syndromes such as lactose intolerance with abdominal pain, gas and diarrhea can also be accompanied by irritability. There are other reasons for being irritable as well. ...Read more

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What is celiac disease in children vs wheat allergy?

What is celiac disease in children vs wheat allergy?

Probably same: An allergy may give you more symptoms but celiac usually attacks the digestive tract. ...Read more

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How do most schools accomodate children with food allergies?

How do most schools accomodate children with food allergies?

Lunch tables: Most schools provide a peanut free table for students with peanut allergy to sit at. They often have a friend that agrees not to bring peanut to school that is able to sit with them. ...Read more

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Is Zantac (ranitidine) (histamine blocker) used for children for allergies.?

Is Zantac (ranitidine) (histamine blocker) used for children for allergies.?

Add-on for hives: Ranitidine (zantac), although it's a different kind of histamine blocker (h2 for acid vs h1 for allergies), has been shown to have some anti-allergy properties, especially when used with an h1 blocker like Benadryl (diphenhydramine) for hives. There was actually one study that showed benefit in nasal allergies, but I don't know anyone that prescribes it for that purpose. ...Read more

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What is a good source of calcium for children that have a cows milk allergy?

What is a good source of calcium for children that have a cows milk allergy?

Depends: There are a variety of sources depending on age and co-existing food allergies. Soy milk is a possible but 30% of cow milk allergic will be allergic to it. Goat milk or cheese, rice milk, etc. Older kids can simply be fed Tums wafers/tablets I a once or twice a day dosing based on size/need. These have enough calcium. The fluid/sugar & fat found in cow milk can be found in many sources. ...Read more

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Please describe a good source of calcium for children that have a milk allergy?

Lots of Stiuff: Fortified soy milk for beginners. Dark leafy greens like spinach, kale, turnips, and collard greens. Fortified orange juice. Sardines. Enriched breads, grains, and waffles. ...Read more

Dr. Steven Griggs
4 Doctors shared insights

Dornase Alfa (Definition)

Dornase alfa ...Read more


Dr. Andrew Berry
6 Doctors shared insights

Pulmozyme (Definition)

Pulmozyme ...Read more