Doctor insights on:
Dopamine Restless Legs
Do Dopamine agonists for Restless Leg Syndrome cross the Blood Brain Barrier? If not, why are side effects like psychosis possible?
The best way to consider akathisia is to imagine the need to move. Patients with this condition have major problems sitting still. They have a need to move. This can be a side effect of medication, may be associated with disease such as parkinsons, or may be a normal variant. Most doctors use it it describe the ...Read more
Restless legs: Studies have shown that more than 60% cases of RLS are inherited as an autosomal dominant inheritance, & that there is deficiency of Dopamine in the part of the brain known as substantia nigra. ...Read more
Hi, I have really bad restless leg syndrome and I have problems with food, I binge. Would this be anything to do with low dopamine levels?
If someone has depression & restless leg syndrome due to renal failure, what type of antidepressant is best. Dopamine agonist, ssri, benzo, or combo.
I have a lot of weakness and akathisia from invega sustenna (paliperidone palmitate). What do I do? I shake my legs a lot is it because of low dopamine? Have to keep moving
You need to discuss: You need to dicuss that with your physicians and then have you see a neurologist ...Read more
What is RLS?: Restless Leg is a condition where you have an uncomfortable sensation (burning, crawling, cramping, aching, tingling, etc.) in you legs that cause an urgent/irresistible need to move your legs (walking, moving legs, messaging, rubbing, etc.). This movement usually occurs when going to bed and can progress to the daytime and sometimes to the arms. See a movement disorder neurologist for Treatment. ...Read moreSee 2 more doctor answers
Multiple: Dopamine agonists work best and include ropinorole, pramipexole, the new Neupro (rotigotine) patch. More traditional meds have included l-dopa, and clonazepam. If you have anemia or kidney disease, better treatment of these conditions may work. Check serum ferritin as some folks may have issues with iron metabolism. Rls is occasionally associated with ms>. ...Read moreSee 2 more doctor answers
NOT FULLY KNOWN: But do find some patients with disruption of iron stores, so, can check ferritin levels. We do find some problem with dopamine issues, and find success in using dopamine agonists, but another approach using Horizant, affects different brain chemicals. May be some genetic links in a few families, and association with a sleep disorder in some also found. ...Read more
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