Doctor insights on:
How do dopamine antagonist help opioid nausea if opioid nause is mediated through opioid receptors and not dopamine?
interrelated: All receptor systems are interrelated and interact with each other. Whatever induces nausea, the reaction is triggered by dopaminergic pathways in a part of the brain called the chemoreceptor trigger zone. Most anti-emetics work by antagonizing dopamine. The combination of opioids and antinausea medications is quite common, both for synergism and to reduce nausea. ...Read more
Most food sources: Dopamine by itself is not found in any food sources but there are two Amino Acids that are converted to Dopamine in the body. Look for foods with phenylananine and tyrosine in them, though this is not very difficult to find. Most meats, dairy, and grains are high in both of these amino acids. ...Read moreSee 1 more doctor answer
See below: Generally speaking we don't measure Dopamine levels. There are diseases where the cells that produce Dopamine start dying (i.e. Parkinson disease). There are diseases where the treatment are anti-dopaminegic medicine (i.e. Schizophrenia, hyperkinetic movement disorders such as huntington disease). I'm not sure that there is any condition where we say the Dopamine level is too high. ...Read moreSee 1 more doctor answer
Dopamine is the : latest fad: The "happy" chemical, right? There's no way that can be answered in 400 characters. Dopamine plays a fundamental role in almost all aspects of behavior from motor control to mood regulation, cognition & addiction & reward. The popular books about it are garbage. See Principles of Neural Science by Kandel & Schwartz or The Biochemical Basis of Neuropharmacology by Cooper, Bloom & Roth. ...Read more
Yes and no: They are both catecholamines, a specific type of chemical class. In the body, there are different type of receptors in tissues which bind catechols with different effects. Dopamine and doubtamine have different affinities for different receptors and thus can have different effects. Kind of like different types of baking sugars...They are all sugars but are used for special purposes and functions. ...Read moreSee 1 more doctor answer
Studies say yes: There are ongoing studies ( and papers) from the NIH, etc that deal with autoimmune-induced damage of the midbrain dopaminergic pathways. Lupus, an auto-immune process is thought to be able to damage or alter this area ( as well as other areas) This would definitely affect the dopamine levels and cause a multitude of possible problems, like depression, etc. ...Read more