Doctor insights on:
Dopamine And Norepinephrine
Please explain what levels of neurotransmitters a tourette patient has to have, serotonin, dopamine, adrenalin & norepinephrine, thank you?
Go after it!: Kenneth, that's a great question. I encourage you to get a Ph.D. in neurobiology and devote your career to finding out the answer, because if you do, you will win about three Nobel Prizes in Medicine. In fact, you'll win if you can find an effective way to measure?neurotransmitters in the living brain all at once for more than a minute at a stretch AT ALL, let alone for Tourette's. ...Read more
Sine seratonin depletes other nerotransmitters like dopamine, norepinephrine, and epinephrine...By "deplete" does it mean a permanent thing?
Not correct: Serotonin does not deplete other neurotransmitters, but there is a balance especially between Dopamine and serotonin. This balance is dynamic and constantly re-establishing itself. Unless there is damage to neurons (which there can be when abusing certain drugs) neurotransmitter changes would not be permanent. ...Read more
What p450 enzymes are inhibited/induced by seroquel, and what does a dopamine/norepinephrine antagonist do? Reduce dopamine levels? Specifics please?
Neither: Seroquel passes through the cyp450 3a4 pathway & is extensively metabolized, but it neither inhibits nor induces the pathway itself. On the other hand, it's metabolism may be significantly affected by other medications. For instance, Dilantin induces the pathway causing seroquel to be rushed through the pathway, leading to less-effective, lower blood levels. Antagonists are blockers. ...Read moreSee 1 more doctor answer
I have been prescribed Vyvanse and Adderal to treat my ADHD for the past six years. I am concerned that my dopamine & norepinephrine levels will not be restored when I get off my Rx. Should I be worried about permanent collateral damage to my brain?
14/male results/ catecholamine norm?
Norepinephrine, supine 136.0 pg/ml
* epinephrine, <10 pg/ml
*dopamine, <10 pg/ml
norepinephrine, stand 457.0 pg/ml
epinephrine, 14.0 pg/ml
dopamine, 16.0 pg/m
Catecholamines: Behavior is much more complex than neurotransmitter levels alone. But norepinephrine (ne) acts mainly in an area of your brainstem called the locus coeruleus. When released, ne triggers the stress response. Ne is also involved in pain, cognition, mood, emotions, movement and blood pressure. Dopamine is involved in regulating mood, pleasure, delusions, psychosis and drug abuse -- and more. ...Read more
Catecholamines: These are both catecholamines, synthesized from the Amino Acid tyrosine. Norepinephrine (ne) acts mainly in an area of your brainstem called the locus coeruleus -- triggering the stress response. Ne is also involved in pain, cognition, mood, emotions, movement and blood pressure. Dopamine is involved in regulating mood, pleasure, delusions, psychosis and drug abuse -- and more. ...Read more
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