Doctor insights on:
Dopamine And Norepinephrine
Please explain what levels of neurotransmitters a tourette patient has to have, serotonin, dopamine, adrenalin & norepinephrine, thank you?
Go after it!: Kenneth, that's a great question. I encourage you to get a Ph.D. in neurobiology and devote your career to finding out the answer, because if you do, you will win about three Nobel Prizes in Medicine. In fact, you'll win if you can find an effective way to measure?neurotransmitters in the living brain all at once for more than a minute at a stretch AT ALL, let alone for Tourette's. ...Read more
Sine seratonin depletes other nerotransmitters like dopamine, norepinephrine, and epinephrine...By "deplete" does it mean a permanent thing?
Not correct: Serotonin does not deplete other neurotransmitters, but there is a balance especially between Dopamine and serotonin. This balance is dynamic and constantly re-establishing itself. Unless there is damage to neurons (which there can be when abusing certain drugs) neurotransmitter changes would not be permanent. ...Read more
What p450 enzymes are inhibited/induced by seroquel, (quetiapine) and what does a dopamine/norepinephrine antagonist do? Reduce dopamine levels? Specifics please?
Neither: Seroquel (quetiapine) passes through the cyp450 3a4 pathway & is extensively metabolized, but it neither inhibits nor induces the pathway itself. On the other hand, it's metabolism may be significantly affected by other medications. For instance, Dilantin induces the pathway causing seroquel (quetiapine) to be rushed through the pathway, leading to less-effective, lower blood levels. Antagonists are blockers. ...Read moreSee 1 more doctor answer
I have been prescribed Vyvanse and Adderal to treat my ADHD for the past six years. I am concerned that my dopamine & norepinephrine levels will not be restored when I get off my Rx. Should I be worried about permanent collateral damage to my brain?
14/male results/ catecholamine norm?
Norepinephrine, supine 136.0 pg/ml
* epinephrine, <10 pg/ml
*dopamine, <10 pg/ml
norepinephrine, stand 457.0 pg/ml
epinephrine, 14.0 pg/ml
dopamine, 16.0 pg/m
Receptors: These three medications are used to support the heart and cardiovascular system ie. blood pressure and heart rate. They are known as sympathomimetics and have a similar response to what you would think of as adrenaline. Each has variable effect on either heart rate, heart function (in terms of strength of 'squeeze') and on blood vessels which would translate to higher blood pressure. ...Read more
Alters physiology: These are very simple answers to a complex question. Levophed (norepinephrine) increases blood pressure; Dopamine increases heart rate, blood pressure and cardiac function (contractility); Dobutamine increases cardiac contractility and heart rate. ...Read moreSee 1 more doctor answer
I was wondering what are the differences of levophed, (norepinephrine) dopamine and dobutamine in terms of their action?
You Asked for It----: Dobutamine- direct b1 receptor stimulant or agonist in the sympathetic nervous system. Levophed- vasoconstrictor peripherally (alpha adrenergic effects) and beta adrenergic stimulant at the level of the heart and coronary vessels dopamine- dual b1 and Alpha adrenergic effects. Useful in hypovolemic shock because of conservancy of renal blood flow. Also, works centrally in other complex ways. ...Read more
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