Doctor insights on:
My partner (female) has ais syndrome (46xy) chromosomes, dr has confirmed presence of uterus but no eggs.Can she stillgive birth through egg donor ivf?
Talk to fertility dr: Too complicated to answer without additional test. It will be unlikely if his 46xy. ...Read more
My cousin is married to her mother's brother's son. Now she is worried whether if she onceives , will her baby be having any genetic mutations ?
Maybe: We are all thought to carry a few recessive genes that do affect us because they are balanced by a normal one. If we marry a sib, they likely carry similar genes and we have a up to 25% risk of a bad pairing/gene with any pregnancy. A cousin would have fewer shared genes but some risk.The closer people are related the more at risk of a genetic disease. ...Read moreSee 1 more doctor answer
Brown over blur: The inheritance of eye color is somewhat complex but when it comes to brown v. blue --- brown is dominant over blue. In your family, Mom and Dad probably have brown eyes but carry one gene for brown and one for blue. There is a 25% chance of a child in this mix with blur eyes. All other combinations will be brown. It is a matter of statistics. ...Read more
My grandmother and my mother both have tested positive for celiac disease. Is this a dominant or recessive trait?
Pcos: AbsolutelyGet a more detailed answer ›
There is a girl, 25yrs. Her mother, grandmother, mothers sister, grandmohters sister had suffered elephantiais. What about her & her children in future?
ELEPHANTIASIS: It is caused by nematode infection , spread by mosquitoes .Dx is by detection of microfilariae in blood, serology or ultrasound of worms. ...Read more
Sister is MTHFR positive. Homozygous w/ 2 abnormal copies of c677t. So one from mom & dad. What are my odds of not having, being hetero or homozygous?
Possibly ¼ for not: Because your mother does not have a normal gene, she can only make eggs with a single copy of c677t, so you will receive one. If your father is heterozygous, your chance of being heterozygous is 50%; if homozygous,, you will be too. Consult a board certified clinical geneticist who will inform you of the evidence-based facts with regard to possible risks. There is much nonsense on the internet. ...Read more
My husbands mother wad diagnosed with myelodysplastic syndrome in her mid 50's , passed away she was deficient of chromosome 8. Is this hereditary?
My husband and his son (by previous marriage) have PKD. His daughter has Polycystic Ovaries, she doesn't show signs of pkd is this random or connecte?
Some cases have : been reported of women with both PKD & PCOS, but the genetic mutations found thus far in patients with Autosomal Dominant & Autosomal Recessive Polycystic Kidney Disease differ from those found in patients with Polycystic Ovarian Syndrome, or Stein-Leventhal Syndrome. Overall, no ^ed rate of PCOS has been found in women with PKD or those who have family members with PKD. ...Read more
Whats the possibility of me having twins if my niece(sisters kid) & cousin(moms sister daughter) all on mymoms side of fam both have twins?
Likely about 1%: General rate of twins is 1%. Your family history is not very strong, and at most would only go up to 2% or so. ...Read more
Is down syndrome dominant , recessive , polygenic inheritance , multiple alleles , sex linked, codominance , or incomplete dominance ?
What are my chances of having twins if both my parents are twins mum identical dad non identical.
Hard to calculate: Your risk would be slightly higher than 1/70. ...Read more
Might be.: Most cases of heterochromia are hereditary, or caused by a disease or an injury. Specific causes of eye color changes include: bleeding (hemorrhage), familial heterochromia, foreign body in an eye, glaucoma, or some of the meds used to treat it, injury, mild inflammation affecting only one eye, neurofibromatosis, waardenburg syndrome. ...Read more
My fiancé has a sister with preder willi's syndrome... What kind of risk does our future child have...is it genetic ?
It's complex: Prader Willi Syndrome is caused by the absence of a small part of chromosome 15 either through a microdeletion or through a phenomenon called uniparental disomy whereby both copies of chromosome 15 come from the mother resulting in the paternally imprinted segment being absent. A more rare situation is one in which the process of imprinting is abnormal in the father. This is because the imprinting gene is defective. The greatest recurrence risk is in this latter situation. Although the imprinting defect can be a spontaneous occurrence there can be up to a 50 percent risk that a normal male sibling will carry it and father a child with PWS. Learning the details of his sister’s chromosome studies and consultation with a genetic counselor can guide recommendations for testing your fiancee and determination of risk for your children. ...Read more
My Husband has multiple sets of fraternal twins on his side and I have identical twins on my side, is the twin gene carried on the male side or woman?
Female Side: Genetic increase for twins is due to female tending to ovulate more than one egg at a time, so trait is for fraternal twins (not identical) and carried by mother. ...Read more
My boyfriends dad is a twin and my half siblings are twins different mom plus I have cousins who were twins What's my chance of having twins?
If grandfather rh- grandmother rh+ ; mother + father both rh+; what is the chance of grandchildren being rh-?
Can't answer: This isn't the best venue for homework help, and since you have not told about the other set of grandparents, and since we have no way of knowing whether the rh-positive grandparent is homozygous or heterozygous, the question isn't answerable. ...Read more
Pls answer grandfather&dad (only child) no cancer grandfather sister 76died ovarian his niece breast cancer 39 fine 30 yrs later >chance genetic ?
Rare: Genetic linkage in cancers are uncommon but they do exist.To better answer the question you should find a medical geneticist.They are often found affiliated with medical schools or childrens hospitals. They can review a multigenerational family tree & share with you current methods to explore the possibility.Some have detectable gene markers that can be found or excluded. ...Read more
Will it b right for a man to marry his father's sister's daughter if there are no close relative marriages in their parents generation.Genetic defect?
Consanguinous marria: We discourage consanguinous marriages because sometimes there are genes that when they meet a second one to make a pair ( i mean on e from father and one from mom), the babies might show severe genetic diseases although there are also very healthy kids from consanguinous marriages. ...Read moreSee 1 more doctor answer
Depends: This depends on the profile of the other parent. Their are dozens of mutations that can lead to CF, although most are the delta 509. Both parents must carry a CF related gene for an offspring to get it, and if so the risk is 25%. Carrier testing is available through specialty labs.If only one has trait ,zero. ...Read moreSee 2 more doctor answers