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Doctor insights on: Does Zoloft Interact With Alcohol Badly

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Does Zoloft (sertraline) interact with alcohol badly?

Does Zoloft (sertraline) interact with alcohol badly?

Yes it does: You should not drink alcohol while taking antidepressants such as zoloft (sertraline). But don't stop spliff so you can drink - just don't drink. ...Read more

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Dr. Donald Jacobson
1,041 doctors shared insights

Sertraline (Definition)

Also called zoloft, (sertraline) is one of selective serotonin reuptake inhibitors, with antidepressant/anti-anxiety actions. May cause headaches, nausea & ...Read more


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What to do if i just started taking Zoloft (sertraline) and i was wondering if its ok to have alcohol?

What to do if i just started taking Zoloft (sertraline) and i was wondering if its ok to have alcohol?

Not advised: Drinking on an ssri antidepressant can make depression or anxiety persist ("fighting" the treatment), & increases seizure risk. The med can also make alcohol feel stronger, impairing driving & similar activities more than expected. The standard rule: avoid all alcohol. That said, people use ssris for months or years, & some use alcohol occasionally in small amts & are ok. Weigh the risks. ...Read more

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What are the short term and long term effects of consuming alcohol while on 200mg of Zoloft (sertraline)? Is 4 to 5 drinks only once in awhile okay?

Not ok.: Zoloft (sertraline) and alcohol should not be mixed per the drug manufacturer. Zoloft (sertraline) may enhance the effect of alcohol. The combination may impact both motor skills and depressive symptoms. Drinking four to five drinks in a sitting is not considered moderation. ...Read more

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How long before/after taking Zoloft (sertraline) can you consume alcohol? I've been takin 100mg at night but like to have a drink with friends every now and then

How long before/after taking Zoloft (sertraline) can you consume alcohol? I've been takin 100mg at night but like to have a drink with friends every now and then

Ask your doctor: Your own physician knows more than we do about your personal history and use of other medications/drugs and/or alcohol. So you should ask him/her about this question to get a personalized answer. Most psychiatrists would suggest not using alcohol at all while being treated with zoloft (sertraline) and other antidepressants. ...Read more

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What is the effects of drinking alcohol and using zoloft (sertraline)? What would happen when you use this together?

What is the effects of drinking alcohol and using zoloft (sertraline)? What would happen when you use this together?

Not a good plan: Using zoloft (sertraline) and alcohol together accentuates the sedating properties of both. Also, alcohol use disrupts the sleep cycle -- which depression does also. Alcohol can worsen existing depression. ...Read more

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What Nighttime cold medication can be taken while on Zoloft (sertraline)? Preferably, one with out alcohol or an antihistamine.

What Nighttime cold medication can be taken while on Zoloft (sertraline)? Preferably, one with out alcohol or an antihistamine.

Talk to doc: If anxiety is causing insomnia, then yous should consult your doctor or psychiatrist to find out the cause. Sleeping pill alone would not be your answer, you need to tackle the cause. ...Read more

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Early i had said about my boyfriend taking the pills lorazepam and Zoloft (sertraline) with alcohol but, he just told me that he took 2 mg. Should he go to the er?

Early i had said about my boyfriend taking the pills lorazepam and Zoloft (sertraline) with alcohol but, he just told me that he took 2 mg. Should he go to the er?

Bad combo: I'm not sure whether you trust your boyfriend to tell you the truth? Earlier you said he was complaining of "feeling weird" after zoloft, (sertraline) lorazepam, and alcohol. I assume you mean 2 mg Lorazepam -- but if there is any question at all about having taken a higher quantity of that or the zoloft, (sertraline) then yes i suggest going to the er. ...Read more

Dr. Alan Ali
993 doctors shared insights

Zoloft (Definition)

Zoloft is a serotonin reuptake blocker which is a kind of ...Read more