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Doctor insights on: Does Your Personality Change With Pernicious Anemia

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Does your personality change with pernicious anemia?

Does your personality change with pernicious anemia?

It can: Pernicious anemia (a severe type of vitamin B12 deficiency) can cause memory problems, irritability, and dementia. Dementia goes beyond having memory problems, and can include difficulties with understanding, reasoning, handling multi-step tasks, and can be accompanied by personality changes. Symptoms generally improve with treatment. ...Read more

Dr. Justin ORourke
73 doctors shared insights

Personality Changes (Definition)

Personality change is a symptom in which a person's personality (the sum of his traits, emotions, behaviors, and thought patterns) has altered. Temporary changes can be due to fatigue, hormonal changes, drug abuse, medication side effects, etc ...Read more


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What symptoms of pernicious anemia are the most common?

What symptoms of pernicious anemia are the most common?

Fatigue: In pernicious anemia, there is no vitamin B12 absorption which causes low red blood cell production and leads to severe anemia. This causes fatigue most comonly. ...Read more

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How to treat pernicious anemia?

How to treat pernicious anemia?

B-12 deficiency: Unless there is an intestinal parasite, we usually just do blood studies to confirm and supplement vitamin b-12 using 1000 mcg injected monthly, i.M. Some pts will absorb sufficient amounts by mouth or intranasal routes, but most efficient to inject. ...Read more

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Is there a cure for pernicious anemia?

Is there a cure for pernicious anemia?

Treatable: This condition can be well treated with life-long use of B12 injections or nasal sprays and results in normalisation of the blood counts. ...Read more

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Does pernicious anemia run in families?

Rarely: Most cases of pernicious anemia are acquired due to immune destruction of the stomach cells which produce intrinsic factor. This results in poor absorption of B12 from food and patients get anemic as a result. Only rarely can children get this as a congenital causes. ...Read more

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Does methadone cause pernicious anemia?

Does methadone cause pernicious anemia?

Not likely: Methadone is a very strong opioid medication, with a long list of serious side effects. But pernicious anemia is NOT one of them. Contact your doctor for specific information about your case, re your anemia and specific doses of methadone you are taking. Anemia may be related to other meds you are taking, or an underlying illness. Check with your MD. ...Read more

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Is pernicious anemia genetically caused?

Not usually: Pernicious anemia is caused by vitamin B12 or Folic Acid deficiency. It may be associated with gastrointestinal or liver problems and should be investigated by your physician. ...Read more

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Is methadone a cause of pernicious anemia?

Is methadone a cause of pernicious anemia?

No: Unaware of any association. True pernicious anemia is an autoimmune disease, caused by antibodies to the cells in our stomachs that produce intrinsic factor, which is needed to absorb vitamin B12 from our intestines. It may be hereditary or acquired. There are other causes of B12 deficiency, including stomach and intestinal diseases/surgery, and lack of B12 in diet. A hematologist can help. ...Read more

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I have pernicious anemia - must i give up alcohol?

I have pernicious anemia - must i give up alcohol?

Certainly: Pernicious anemia is due to vitamin B12 deficiency. Alcohol in many ways can contribute to B12 deficiency: 1. Interferes with b vitamin absorption - alcoholics also do not have enough b vitamins in their diet 2. May cause gastritis leading to poor acid secretion in stomach (acid helps B12 absorption) 3. May cause intestinal damage leading to malabsorption. Thus, better to avoid alcohol! ...Read more

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How does pernicious anemia cause people to have achlorhydria?

The other way around: Achlorhydria (lack of adequate gastric acid production and secretion) is one of the causes of pernicious anemia and not the other way around. Normal gastric acid is essential for adequate absorption of vitamin b-12. Vitamin b-12 deficiency in turn causes pernicious anemia. ...Read more

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Pernicious Anemia (Definition)

A decrease in red blood cells when the body can't ...Read more


Dr. Steven Ginsberg
1,273 doctors shared insights

Anemia (Definition)

Any condition where there is a decrease in the red blood ...Read more