Top
10
Doctor insights on: Does Taking Tamoxifen Benefit Women With Cdis

Share
1

1
Does taking tamoxifen benefit women with cdis?

Does taking tamoxifen benefit women with cdis?

Yes.: Women with a history of ductal-carcinoma-in-situ (dcis) may have a 50% reduction in developing a second breast cancer when taking tamoxifen for 5 years ("chemoprevention"). Furthermore, following a lumpectomy, the combination of tamoxifen and radiation therapy may have a decreased risk of cancer recurrence in the affected breast greater than either therapy alone. ...Read more

See 1 more doctor answer
Dr. Sean Canale
638 doctors shared insights

Tamoxifen (Definition)

This medication is used to: treat breast cancer that has spread to other parts of the body in men and women. Treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy. Reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (dcis; a type of breast cancer ...Read more


2

2
Does taking tamoxifen really benefit dcis?

Does taking tamoxifen really benefit dcis?

Yes, for ER+ DCIS: The addition of tamoxifen to surgery and radiation therapy for dcis significantly reduced the risk of invasive cancer on the same beast by 40 % and risk for in situ breast cancer on the other breast by 60 percent. ...Read more

See 1 more doctor answer
3

3
What are the common benefits of tamoxifen?

What are the common benefits of tamoxifen?

Kill cancer cells: Tamoxifen is a very effective chemotherapeutic agent to treat breast cancers that have the estrogen receptor. Tamoxifen may also be prescribed to prevent breast cancer in high-risk women: a 5-yr regimen may reduce the lifetime risk of breast cancer by 50%. ...Read more

See 1 more doctor answer
4

4
Do pre-menopausal women usually gain weight on tamoxifen?

Do pre-menopausal women usually gain weight on tamoxifen?

No: There have been many studies that have compared tamoxifen to placebo, demonstrating it's effectiveness treating breast cancer; none of these studies, to my knowledge, ever showed any difference between tamoxifen and placebo regarding weight gain. Nevertheless, as many as 10% of women on tamoxifen do report weight gain. This may be due to post-chemotherapy effects or menopause, as well. ...Read more

See 1 more doctor answer
5

5
I read that premenapausal women can get osteoporosis from tamoxifen, but postmenapausal cannot, is this true?

I read that premenapausal women can get osteoporosis from tamoxifen, but postmenapausal cannot, is this true?

In certain group: Tamoxifen is preserving bone density/decrease bone loss in postmenopausal women and in women who developed chemotherapy-induced amenorrhea. However, in premenopausal women who continued to menstruate after adjuvant chemotherapy, tamoxifen usage was associated with bone loss. ( jco 2006). ...Read more

See 1 more doctor answer
6

6
Why d & c is needed if a woman does not have no bleeding and thinks she menopausal because of her advance age which is 54year. Currently on tamoxifen?

Why d & c is needed if a woman does not have no bleeding and thinks she menopausal because of her advance age which is 54year. Currently on tamoxifen?

Not sure: Tamoxifen increases your risk of uterine cancer. If you had an ultrasound that showed thickened uterine lyning, your doctor may want to do a d;c to check for precancerous condition of your uterus. Without an abnormal ultrasound and without postmenopausal bleeding, i can't think of any reason why you need a d;c. ...Read more

7

7
Why women taking Tamoxifen suffer from the risk of developing other cancers of the reproductive tract in comparison to all other women ?

Why women taking Tamoxifen suffer from the risk of developing other cancers of the reproductive tract in comparison to all  other women ?

Hormone effect: In the breast tamoxifen blocks any estrogen activity but in the uterus it is just the opposite where tam stimulates the uterine lining just like estrogen. This can causes overgrowth of the lining (endometrial hyperplasia) which is a risk for cancer. The same risk is present with hormone replacement with estrogen only which is why progesterone needs to be given as well with HRT. ...Read more

8

8
A female has pcos taking clomophen and tamoxifen and metformin has elevated liver enzymes what is the cause?

A female has pcos taking clomophen and tamoxifen and metformin has elevated liver enzymes what is the cause?

Multiple reasons: It is possible that the metformin affected that. But...Many women with pcos have high insulins and sugars and this leads to chronic fatty liver which is the more common reason for those findings. An ultrasound of the liver would help. ...Read more

9

9
Oncologist started me on Effexor (venlafaxine) XR for the hot flashes from tamoxifen.Taking it for 1 week extremely tired & nausea.Will benefits outweigh sideeffect?

Oncologist started me on Effexor (venlafaxine) XR for the hot flashes from tamoxifen.Taking it for 1 week extremely tired & nausea.Will benefits outweigh sideeffect?

Probably not: Nausea and fatigue are common side effects of effexor (venlafaxine). They can resolve with continued use of the med but often require that the Effexor (venlafaxine) be stopped. There are other meds that can help the hot flashes. ...Read more

See 2 more doctor answers
10

10
Is combined tamoxifen plus hormonal therapy more effective in pre or postmenopausal women and why?

Is combined tamoxifen plus hormonal therapy more effective in pre or postmenopausal women and why?

Tamoxifen: We don't give tamoxifen in combination with hormone replacement in the us. Occassionally use vaginal very low dose estrogen cream for vag dryness and tell pts to use a little as they can to relieve symptoms. Blocking hormones and giving them at same time does not make much sense. ...Read more