Top
40
Doctor insights on: Does Systemic Lupus Erythematosus Sle Cause Kidney Damage

Share
1

1
How are systemic lupus erythematosus, coma & leukopenia related?

How are systemic lupus erythematosus, coma & leukopenia related?

SLE: Is a systemic disease and is a form of vascullitis, which means that there is inflammation in the blood vessels as a result it is a multi-system disease and can affect any organ in the body. When the brain is affected it can lead to changes in mood, psychosis and even coma. Leukopenia is a recognized feature of SLE at some point in the course of the disease. It can affect the kidneys, joints etc ...Read more

Kidney (Definition)

The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more


2

2
Can lupus cause pancreatitis since lupus is an autoimmune disease?

Can lupus cause pancreatitis since lupus is an autoimmune disease?

Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read more

See 1 more doctor answer
3

3
Can lupus cause pancreatitis since lupus is an autoimmune disease?

Can lupus cause pancreatitis since lupus is an autoimmune disease?

Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read more

See 2 more doctor answers
4

4
What systems does lupus nephritis affect?

What systems does lupus nephritis affect?

The kidney: Lupus nephritis by definition is the kidney and this is the system affected. However, SLE rarely just affects the kidney alone and other systems including skin, joints, heart, lungs, nervous system, an also be affected by lupus. Lupus nephritis requires major treatment by a specialist. ...Read more

5

5
What systems does lupus nephritis affect?

What systems does lupus nephritis affect?

Autoimmune, systemic: Lupus can affect any part of the body. Common symptoms - joint pains, facial rash, photosensitivity, mouth ulcers, hair loss. Organ involvement usually kidney, brain, heart can occur ...Read more

See 2 more doctor answers
6

6
Systemic lupus erythematosus--what is sle?

Systemic lupus erythematosus--what is sle?

Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read more

See 1 more doctor answer
Dr. Paul Grin Dr. Grin
2 doctors agreed:
7

7
Can lupus cause tooth resorption? Can lupus cause Crohn's disease?

Dr. Paul Grin Dr. Grin
2 doctors agreed:
Can lupus cause tooth resorption? Can lupus cause Crohn's disease?

Definitely, no: The studies show that dentin is not recognized as a self structure by the immunologic system, being the component of the tooth makes it impossible. Hope it helps. ...Read more

8

8
Is systemic lupus erythematosus fatal?

Sometimes.: Sle is generally treated with good response, but unfortunately it is sometimes fatal. ...Read more

See 1 more doctor answer
9

9
How can one cure systemic lupus erythematosus?

How can one cure systemic lupus erythematosus?

No cure but ...: Lupus cannot be cured but the symptoms can often be controlled. In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Lupus can be mild. Many lupus patients have non-life threatening disease. Lupus can be severe. Kidney or brain involvement portends a worse prognosis. ...Read more

10

10
Whats death rate related to systemic lupus erythematosis?

Whats death rate related to systemic lupus erythematosis?

Less now: In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Many lupus patients have non-life threatening disease. Kidney or brain involvement portends a worse prognosis. ...Read more

13

13
With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

SLE DPGN is bad.: The degree of remaining renal function dictates the inability of the kidney to excrete waste products and manage potassium levels. In any severe kidney disease when egfr approaches 15 ml/min uremia and elevated k+ levels are frequently noted. ...Read more

See 1 more doctor answer
14

14
Can plaquenil (hydroxychloroquine) (for autoimmune disease) cause increased infections?

Can plaquenil (hydroxychloroquine) (for autoimmune disease) cause increased infections?

Not commonly: Unlike many meds used to treat autoimmune diseases (immune modulators that suppress the immune system) Plaquenil (hydroxychloroquine) has an antiinflammatory effect on autoimmune dss. So the risk of infections (seen with immune suppression) is uncommon. Major concern with this drug is effect on vision. Regular eye exams are recommended. ...Read more

15

15
Does nephrogenic systemic fibrosis only affect people with kidney problems?

Does nephrogenic systemic fibrosis only affect people with kidney problems?

Yes: Most cases (~90%) of nephrogenic systemic fibrosis (NSF) have been reported in patients with end-stage kidney disease (ESKD). The remaining cases have occurred in patients with advanced CKD or acute kidney injury. ...Read more

16

16
Does lupus cause hives?

Does lupus cause hives?

Lupus can cause hives, but this is uncommon: The exact cause of hives in lupus isn't clear. But it may be due to certain antibodies produced by some people with lupus. Sun exposure also may play a role. In addition, some of the medications used to treat lupus may cause side effects that include hives. Individual hives usually last less than 24 hours. Individual hives that last longer than 24 hours may be due to urticarial vasculitis, a condition characterized by inflammation of the small blood vessels in the skin. Lupus is one cause of urticarial vasculitis. Signs and symptoms of urticarial vasculitis include an itching and burning sensation in the affected skin. Unlike hives, wheals caused by urticarial vasculitis may leave behind a bruise. A doctor may confirm a diagnosis of urticarial vasculitis by a biopsy of the affected skin. Treatment of hives may include: Antihistamines, H-2 blockers (cimetidine, ranitidine), Corticosteroids. Treatment of urticarial vasculitis also may include antihistamines, H-2 blockers and corticosteroids, but used for a longer time than with simple hives. Aggravating factors, such as sun exposure, also may need to be controlled. ...Read more

18

18
Can systemic lupus erythematosus cause swelling in one hand?

Can systemic lupus erythematosus cause swelling in one hand?

Yes: A common symptom of sle is arthritis or joint pain and swelling which can involve just one hand. Usually there will be other symptoms as well such malar rash (red rash over the cheeks), increased sensitivity to sun, possibly hair loss and rash on the body, hands or knuckles or scalp. ...Read more

19

19
What is trigger systemic lupus erythematosus in antiquity?

Mysterious lupus: It is not known what causes lupus erythematosus. Referring to antiquity, lupus was used to describe several different rashes. It could be autoimmune, where the body attacks itself such as lupus erythematosus or discoid lupus. It could be caused by tuberculosis infection such as lupus vulgaris. It could be related to another inflammatory disease such as sarcoidosis which causes lupus pernio. ...Read more

20

20
Does prednisone cause kidney damage?

Does prednisone cause kidney damage?

No it does not: No Prednisone does not cause kidney damage.Long term use of Prednisone with moderate to high doses of Prednisone can cause elevation of blood pressure, but if the dose is reduced or Prednisone is stopped, the blood pressure comes down to normal. But no kidney damage. ...Read more

21

21
Is there a cure for systemic lupus erythematosus (sle)?

SLE treatment: Systemic lupus erythematosus (sle) is a long-term autoimmune disorder that may affect the skin, joints, kidneys, brain, and other organs. There is no cure for sle. The goal of treatment is to control symptoms. ...Read more

See 1 more doctor answer
22

22
What are some alternative therapies for sle (systemic lupus erythematosus)?

What are some alternative therapies for sle (systemic lupus erythematosus)?

None: Diet and omega 3 fatty acids may help but there are no specific vitamin or herbal supplements for sle. Avoiding sugar and dairy is helpful for some people. Omega three fatty acids along with vitamin c and b complex may reduce symptoms. ...Read more

See 1 more doctor answer
23

23
Systemic lupus erythematosus--what is sle?

Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read more

See 1 more doctor answer
24

24
Can systemic lupus erythematosus cause swelling in one hand?

Yes: A common symptom of sle is arthritis or joint pain and swelling which can involve just one hand. Usually there will be other symptoms as well such malar rash (red rash over the cheeks), increased sensitivity to sun, possibly hair loss and rash on the body, hands or knuckles or scalp. ...Read more

25

25
Can active systemic lupus erythematosus be caused by prescription medication? Need expert opinions!

Drug-induced lupus: Yes, some prescription medications can definitely cause drug-induced lupus which often will resolve after the drug is stopped. Many of the drugs that can cause lupus do NOT cause lupus in the majority of people treated with them. There may be genetic susceptibility to drug-induced lupus and/or the right trigger. Many possible meds. Best way is to be evaluated by a board certified rheumatologist ...Read more

26

26
With acute diffuse proliferative glomerulonephritis caused by systemic lupus erythematosus, why would a patient have uremia and hyperkalemia?

SLE DPGN is bad.: The degree of remaining renal function dictates the inability of the kidney to excrete waste products and manage potassium levels. In any severe kidney disease when egfr approaches 15 ml/min uremia and elevated k+ levels are frequently noted. ...Read more

See 1 more doctor answer
29

29
What can I use for systemic lupus erythematosus symptoms if I don't have a new doctor yet?

Many but need doctor: The first thing to do is define your lupus, everyone with lupus is different.You need to contact your physician - see a rheumatologist, define your lupus and then you decide on your treatment. Not everyone with lupus needs meds, but you need good health habits - no smoking, exercise, etc defining your type of lupus will clarify the best medications for you to take. ...Read more

30

30
Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Does highly elevated antinuclear antibody result always mean systemic lupus erythematosus?

Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read more

See 1 more doctor answer
31

31
Is the cognitive dysfunction that results from systemic lupus erythematosus typically permanent?

It depends: Lupus can cause both reversible and irreversible changes to the nervous system, and these can affect personality, memory, and other basic aspects of patients' lives. That said, simply being sick can aggravate depression, sleep deprivation, etc. Controlling pain and other disruptive elements of the disease, can improve quality of life and help people be more who they would like to be. ...Read more

See 1 more doctor answer
Dr. John Chiu Dr. Chiu
2 doctors agreed:
32

32
Prednisone is most likely to be indicated in the management of systemic lupus erythematosus due to what?

Dr. John Chiu Dr. Chiu
2 doctors agreed:
Prednisone is most likely to be indicated in the management of systemic lupus erythematosus due to what?

Antiinflammatory: Prednisone suppresses inflammation and thus it is intended to control the inflammation resulting from many diseases including lupus and rheumatoid arthritis. It is not a cure or specific for any disease , just a temporary solution. Long term high-dose prednisone can lead to many serious side effects. ...Read more

See 1 more doctor answer
33

33
What is the definition or description of: systemic lupus erythematosus diagnostic panel?

Labs for a + ANA: The antinuclear antibody test (ANA) is the initial screening test for lupus, but since it produces a lot of false positives, follow up testing for other auto antibodies is needed. The other tests in the panel are usually more specific for lupus, but less sensitive. Panels sometimes produce dubious results, so any positive test has to be taken in context. ...Read more

See 1 more doctor answer
34

34
How much should people with systemic lupus erythematosus pay extra for the insurance in usa?

None: The reason that insurance exists is to spread the risk of any single person having any disease is divided among many healthy people with no disease.Our current system is prejudiced against anybody with a "pre-existing" illness such as yours and makes you pay extra.Makes getting insurance(or keeping it ) tough.It is a lose-lose;dr and patient, win for insurance company.My gripe with aca. ...Read more

35

35
Docs can you explain what is 'systemic lupus erythematosus' in clear details?

Docs can you explain what is 'systemic lupus erythematosus' in clear details?

An auto immune disea: Systemic lupus is a auto immune disease that can affect any part of the body.The immune system of the patient attacks its own body cells and tissues, and that causes inflammation and damage to the tissues it most often affecrs heart, skin.Joints, blood vessels, lungs, kidneys , liver and nervous system the incidence of sle is 9 times in women than men. ...Read more

Dr. Alfred Kim Dr. Kim
2 doctors agreed:
37

37
What gene causes lupus erythematosus?

Dr. Alfred Kim Dr. Kim
2 doctors agreed:
What gene causes lupus erythematosus?

Many genes: The previous answer is right with several genes associated with lupus, but no one knows how those genes cause disease. I think it's important to remember that there is likely many ways to develop lupus symptoms, and this will vary between people. So some of these known genes will be important for some, and not important for others. As we sequence more patients, we'll have more answers. ...Read more

See 1 more doctor answer
38

38
Why is the butterfly rash in systemic lupus erythematosus?

Why is the butterfly rash in systemic lupus erythematosus?

Thin skin: Thin area around the nose/cheeks is very sensitive to sun and the first to show sle signs. ...Read more

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
39

39
Is systemic lupus erythematosus a kind of cancer disease, and is it fatal?

Dr. Liawaty Ho Dr. Ho
3 doctors agreed:
Is systemic lupus erythematosus a kind of cancer disease, and is it fatal?

Not a cancer: Sle is an autoimmune disease that can affects multiple organ including kidney, brain, joints, skin, blood, eyes etc. It is not cancer. Yes, it can be very debilitating and lethal if not treated properly. You need to see a rheumatologist and discuss in detail with your md. ...Read more

See 3 more doctor answers
40

40
What are the risks of getting your wisdom teeth extracted with systemic lupus erythematosus?

Depends: If you have been on steroids recently for flare ups of sle, it could lead to post operative complications. Also, there is always a chance that there may be a latent cardiac problem that will only become apparent when you are under stress, like during a surgery. I would see and oral surgeon, and have him/her work with your physician to manage your case safely. ...Read more

See 1 more doctor answer
Dr. Patrick Sweet III
169 doctors shared insights

Kidney Damage (Definition)

Kidney damage is a condition that may be due to damage to the blood vessels connected to the kidney or injuries from causes such as tumors and certain medications. Symptoms may include blood in the urine, an inability to urinate, and pain in the back of the upper abdomen on either ...Read more


Systemic (Definition)

A condition that involves the whole body as compared to a part of the body. For example diabetes ...Read more