Doctor insights on:
Does Systemic Lupus Erythematosus Sle Cause Antiphospholipid Syndrome
Autoimmune disease: A disease in which your body makes antibodies against your own cells. These antibodies cause destruction and inflammation which produce a wide variety of symptoms depending on what cells are being injured. There are some common symptoms and signs with the disease, but just about any symptom could be produced by lupus. ...Read moreSee 1 more doctor answer
Many genes: The previous answer is right with several genes associated with lupus, but no one knows how those genes cause disease. I think it's important to remember that there is likely many ways to develop lupus symptoms, and this will vary between people. So some of these known genes will be important for some, and not important for others. As we sequence more patients, we'll have more answers. ...Read moreSee 1 more doctor answer
Mysterious lupus: It is not known what causes lupus erythematosus. Referring to antiquity, lupus was used to describe several different rashes. It could be autoimmune, where the body attacks itself such as lupus erythematosus or discoid lupus. It could be caused by tuberculosis infection such as lupus vulgaris. It could be related to another inflammatory disease such as sarcoidosis which causes lupus pernio. ...Read more
Not always: Unfortunately, there is no single laboratory test that absolutely rules in or out systemic lupus erythematosis (sle). Although a highly positive antinuclear antigen (ANA) is common in sle, diagnosis is based on a careful history, physical exam and laboratory evaluation. ...Read moreSee 1 more doctor answer
SLE: Is a systemic disease and is a form of vascullitis, which means that there is inflammation in the blood vessels as a result it is a multi-system disease and can affect any organ in the body. When the brain is affected it can lead to changes in mood, psychosis and even coma. Leukopenia is a recognized feature of SLE at some point in the course of the disease. It can affect the kidneys, joints etc ...Read more
Lupus: Lupus comes in 4 major types: systemic, discoid (skin only), neonatal, and drug-induced. Some people who have an abnormality in their immune system and fail to make a body defense protein called complement are also at risk for developing lupus. It has been estimated that 1.5 million people in the US have one of these lupus forms. Women are 2-3 times more likely to develop this disease than men. ...Read moreSee 1 more doctor answer
Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read moreSee 1 more doctor answer
Lupus pancreatitis : Lupus induced pancreatitis happens in a small percentage of lupus patients . Lupus vasculitis can cause pancreatitis. Other causes of pancreatitis in lupus include virus induced, perforated peptic ulcer disease, common duct stone from biliary tract, alcohol and or drug induced . Pancreatitis in lupus occurs as part of multi system disease. Pancreatitis as initial manifestation lupus is rare. ...Read moreSee 2 more doctor answers
No cure but ...: Lupus cannot be cured but the symptoms can often be controlled. In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Lupus can be mild. Many lupus patients have non-life threatening disease. Lupus can be severe. Kidney or brain involvement portends a worse prognosis. ...Read more
Lupus can cause hives, but this is uncommon: The exact cause of hives in lupus isn't clear. But it may be due to certain antibodies produced by some people with lupus. Sun exposure also may play a role. In addition, some of the medications used to treat lupus may cause side effects that include hives. Individual hives usually last less than 24 hours. Individual hives that last longer than 24 hours may be due to urticarial vasculitis, a condition characterized by inflammation of the small blood vessels in the skin. Lupus is one cause of urticarial vasculitis. Signs and symptoms of urticarial vasculitis include an itching and burning sensation in the affected skin. Unlike hives, wheals caused by urticarial vasculitis may leave behind a bruise. A doctor may confirm a diagnosis of urticarial vasculitis by a biopsy of the affected skin. Treatment of hives may include: Antihistamines, H-2 blockers (cimetidine, ranitidine), Corticosteroids. Treatment of urticarial vasculitis also may include antihistamines, H-2 blockers and corticosteroids, but used for a longer time than with simple hives. Aggravating factors, such as sun exposure, also may need to be controlled. ...Read more
1280 ANA, -ENA and compliments. lupus symptoms, but rheum said no lupus because I have Blau Syndrome, rare autoinflammatory, doesn't cause ANA. Help!
Talk to your MD: Blau syndrome, systemic granulomatous syndrome, is a rare autoimmune disease affecting many organs. It can simulate, at least initially, other autoimmune diseases. There is effective treatment for most patients with the disease. Either talk with your rheumatologist or go to a tertiary medical center. ...Read more
Less now: In the 1950s, 60% of lupus patients died within five years. Now, more than 90% survive beyond five years. Many lupus patients have non-life threatening disease. Kidney or brain involvement portends a worse prognosis. ...Read more
Systemic lupus/teens: Yes it can appear in teens.Get a more detailed answer ›
It is magic?: 1the use of anti-malarials in autoimmune diseases was accidentally discovered in treating wwii vets for malaria. Those with RA improved. Chloroquine and ho-q were tested in sle, with very positive results. In the early 80's canadian researchers definitively showed fewer sle flares with ho-q. It is considered the rx of first choice for :sle. We now understand more of the mechanisms, but not all. ...Read more
Can you explain the diagnosisof purpura fulmicans and lupus anticoagulant w/possible phophosilid syndrome?
No: This is a question that can be adequately answered only by complicated drawings, references to appropriate testing of several clotting factors, and analysis by a rheumatologist and a hematologist. In my patients such a discussion would take at least an hour. Hire a hematology consultant. ...Read more
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