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Doctor insights on: Does Stage 3 Kidney Disease Cause Low Blood Counts

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Can Stage 3 kidney disease & kidney stones cause minor anemia & low TIBC? Thank you.

Can Stage 3 kidney disease & kidney stones cause minor anemia & low TIBC? Thank you.

Yes: It can definitely cause anemia in what we call anemia of inflammation. It is also known as anemia of chronic disease. The kidneys secrete an important hormone called erythopoetin which helps with the production of red blood cells. For this reason, you have anemia of chronic disease. You should definitely have iron studies drawn and see if you are a candidate for medication. ...Read more

Kidney (Definition)

The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more


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Why does kidney disease cause anemia? Epo?

Why does kidney disease cause anemia? Epo?

Anemia in CKD: Chronic kidney disease (ckd) anemia is caused by the diseased kidneys not being able to make the hormone, erythropoietin (e). E stimulates the bone marrow to make new red blood cells. Epogen (epoetin alfa) is a man made drug that replicates e's affects on the bone marrow and is given to both CKD and dialysis patients to treat their anemia. ...Read more

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55gfr kidney damage n high blood pressure can this cause kidney failure?

55gfr kidney damage n high blood pressure can this cause kidney failure?

Possible...: All life events are a one-way street of accumulation, modification, and continuation from inception to eternity. So. good/adequate personal & professional care can modify the existing conditions so to slow down the pace of worsening, which may highly vary. Nonetheless, move on to do those within our control and avoid wasting time & energy to think and worry about those beyond our control. Best ... ...Read more

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How does high blood pressure cause kidney failure?

How does high blood pressure cause kidney failure?

Blood vessel damage: High blood pressure damages the blood vessels, especially small arteries and that damages the special organs in kidneys, glomeruli. Hypertension also damages larger arteries and reduced blood supply to kidneys. ...Read more

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Does fluid on kidney, reactive hypoglycemia, elevated cholesterol and blood pressure and egfr of more than 60 mean I have mild kidney disease?

Does fluid on kidney, reactive hypoglycemia, elevated cholesterol and  blood pressure and egfr of more than 60 mean I have mild kidney disease?

No: Egfr > 60 is good (the higher the better). Otherwise, you mention nothing that confirms kidney disease. Fluid around kidney needs followup. Blood pressure over time may hurt your kidney. Exercise to reduce this and cholesterol. Eat healthy as much as possible! ...Read more

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Why does anemia cause progression of chronic kidney disease?

Why does anemia cause progression of chronic kidney disease?

Reversed sequence: Progression of chronic kidney disease results in development of anemia because kidney is no longer able to produce erythropoietin, a hormone enhancing red blood cell production from bone marrow. ...Read more

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Does lymphedema mean you have liver damage, high blood pressure, cancer of lymphs, or hypertension?

Does lymphedema mean you have liver damage, high blood pressure, cancer of lymphs, or hypertension?

No: Lymph edema means you have swelling of an arm or leg due to some obstruction of the lymphatic system. Prior surgery and trauma can damage the lymphatics and cause lymphedema. ...Read more

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What is the prognosis of liver cirrhosis with stage 4 liver cancer? Why people with liver cirrhosis/liver cancer have low hemoglobin, red blood cells?

What is the prognosis of liver cirrhosis with stage 4 liver cancer? Why people with liver cirrhosis/liver cancer have low hemoglobin, red blood cells?

Need to ask your ono: Your oncologist can help. Anemia can be caused by blood loss(which is common in patients with cirrhosis(GI blood loss due to varices). Poor blood formation is also common(Anemia of chronic disease). Blood transfusion can help the pateint. Keep Hemoglobin near 10 Grams. There is some treatment for Liver cancer that could be tried(the medicine is called Nexavar(Sorafenib) ...Read more

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Does low c3c combined with low phosphate levels always mean you have kidney disease?

Does low c3c combined with low phosphate levels always mean you have kidney disease?

No: Often c3 complement levels are a nonspecific marker of other possible problems like infection or autoimmune inflammation or lupus perhaps. But if you have normal kidney function otherwise that may not be the case. You might need to have your kidney function looked at more closely to be sure of this with other tests first. ...Read more

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Does low ionized calcium level in the blood mean having kidney disease? Please explain.

Does low ionized calcium level in the blood mean having  kidney disease? Please explain.

Not necessarily: There are other more common causes, like Vitamin D deficiency. Typically if someone has checked your calcium they have also checked your kidney function (specifically creatinine), so if you are worried about your kidneys you could ask your doctor. ...Read more

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What can cause high Active (holotranscobalamin) B12 levels in blood, when red & white cell & platelet counts, liver & kidney function are all normal?

What can cause high Active (holotranscobalamin) B12 levels in blood, when red & white cell & platelet counts, liver & kidney function are all normal?

It's just you: This test itself is not mainstream. It is experimental. A high value on a B12 is never a clinical concern. Reference ranges at real labs are set so that a few percent of healthy folks fall outside on either end. ...Read more

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Wouldn't malnutrition due to Crohn's disease cause an abnormal Prealbumin blood level?

Wouldn't malnutrition due to Crohn's disease cause an abnormal Prealbumin blood level?

Pre-albumin / Crohns: Yes depending on level of inflammation in crohns disease. As a gastroenterologist I use pre-albumin in conjunction with other blood tests to see how my patients are responding to therapy. If inflammation is poorly controlled pre-albumin is usually low. ...Read more

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Renal functions. Patient has extemely low blood pressure caused by congestive heart failure; what causes this?

Renal functions. Patient has extemely low blood pressure caused by congestive heart failure; what causes this?

Renal function CHF: With congestive heart failure, the cardiac output or amount of blood the heart pumps is reduced. The kidneys are now also receiving less blood and it affects them. But! do not forget that all of the factors that caused CHF in the first place have also affected the kidneys (high blood pressure, diabetes, cholesterol...Etc). ...Read more

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My ultrasound said abnormal resistive index on r kidney suggesting medical renal disease or renal stenosis. My kidney blood levels were all low?

My ultrasound said abnormal resistive index on r kidney suggesting medical renal disease or renal stenosis. My kidney blood levels were all low?

High Resistive Index: I have two questions, why did your doctor order a resistive index on you? Do you have hypertension (BP) that is difficult to control? If you do not have any bp, then you likely do not have a renal artery stenosis (ras). If you do have bp, you may need a renal artery angiogram to see if your BP is caused by a ras. See a nephrologist for more answers. Good luck. ...Read more

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Mom with DLB diagnosed with benign tumor on adrenal gland in February. One month later I'm told she has Stage 3 Kidney Disease based on blood work. ?

Mom with DLB diagnosed with benign tumor on adrenal gland in February. One month later I'm told she has Stage 3 Kidney Disease based on blood work. ?

Not sure: Dx of a benign adrenal tumor is made on scan with a solitary small nodule in adrenal. Occassionally known mets to adrenal appear as small nodules iel lung, melanoma, breast to adrenal. If kidney tumor was present it would have shown up on scan. Dx of kidney cancer not made on blood test, there is no marker for kidney. Angiogram, PET/CAT and bx of lesion used to make dx. ...Read more

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Can Stage 3 kidney disease & kidney stones cause minor anemia & low TIBC? Thank you.

Yes: It can definitely cause anemia in what we call anemia of inflammation. It is also known as anemia of chronic disease. The kidneys secrete an important hormone called erythopoetin which helps with the production of red blood cells. For this reason, you have anemia of chronic disease. You should definitely have iron studies drawn and see if you are a candidate for medication. ...Read more

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Can low thyroid mask symptoms of high blood pressure caused by kidney disease? Is blood pressure of 170/150 a medical emergency?

Can low thyroid mask symptoms of high blood pressure caused by kidney disease? Is blood pressure of 170/150 a medical emergency?

BP of 170/150: Your blood pressure is significantly elevated and is, therefore, poorly controlled. Your hypothyroidism is not masking it. As a young woman, you need to speak to your physician (P) about either increasing your BP meds, from one to more agents and considering the fact that you have secondary hypertension (SH) and working up for that possibility. See you P for more help, as your P knows you best. ...Read more

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Help! could stage 3 kidney disease cause constipation?

Help! could stage 3 kidney disease cause constipation?

Yes: The diet/medications that we use for people with stage 3 ckd can cause constipation. Use of metamucil or its generic equivalent is generally all that's needed to overcome this. However, this can worsen as the kidney disease progresses. Since the colon is responsible for up to 60% of potassium excretion in patients with advanced kidney disease, you need to work closely with your doc to avoid this. ...Read more

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I have stage 3 kidney disease and and used a fleet rectal enema for constipation I later found out it may cause kidney failure. Should I be worried?

I have stage 3 kidney disease and and used a fleet rectal enema for constipation I later found out it may cause kidney failure.  Should I be worried?

Yes it can: It contaions monobasic sodium phosphate and dibasic sodium phosphatase heptahydrate which is rarely known to cause kidney failure in certain individuals sometimes, it has been reported but it is very rare, and happens in people with normal kidneys. ...Read more

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Which mechanism in kidney disease causes high blood pressure?

Which mechanism in kidney disease causes high blood pressure?

Kidney disease - BP: The two principal mechanisms are salt retention by impaired kidneys and secretion of renin from injured / compromised macula densa islands. Renin activates angiotensin which is a potent vessel constrictor and salt retainer; so kidney disease generates hi BP and kidneys are harmed further by hi BP - - - thus kidneys are "victim" to HIBP and kidneys "are villains" _ generating hiBP ....... ...Read more

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I have swelling feet and calves. What could be the cause? I was checked for kidney disease and all is fine. All my blood is fine. What else could it b

I have swelling feet and calves. What could be the cause? I was checked for kidney disease and all is fine. All my blood is fine. What else could it b

See below.: Edema of the lower extremities comes from liver or kidney disease or from heart pump failure or to leaky vessels or excess sodium in diet. See doc to make sure we have crossed all items off list. If none of the above it is idiopathic edema caused by a slight imbalance in the hydrostatic pressures in the leg vessels. Sometimes due to prior infection / trauma or obesity. ...Read more

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Does low ionized calcium level in the blood mean having kidney disease? Please explain.

Not necessarily: There are other more common causes, like Vitamin D deficiency. Typically if someone has checked your calcium they have also checked your kidney function (specifically creatinine), so if you are worried about your kidneys you could ask your doctor. ...Read more

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Can chronic kidney disease cause peripheral neuropathy.?. I have normal blood sugars.

Can chronic kidney disease cause peripheral neuropathy.?. I have normal blood sugars.

Potentially yes: Peripheral nerve problems could be due to secondary metabolic imbalances due to the renal issues, but also could be complication of medications you are using, and of course could be due to a co-morbidity associated with an additional disorder. There may well be one unitary disorder causing both kidney and nerve dysfnctn. ...Read more

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Do you need to be on a special diet if you have stage three kidney disease. And my blood pressure is fine with medication, but I am anemic.

Do you need to be on a special diet if you have stage three kidney disease.  And my blood pressure is fine with medication, but I am anemic.

Low sodium: Low sodium diets are essential to avoiding hypertension and may slow the loss of kidney function. A recent article suggests maintaining a low phosphorous level and there is data from the 1970's to support this. There a phosphorous restricted diet is reasonable as long as you are not already malnourished. Anemia is common with ckd. Check iron levels. Replace with oral or IV iron if low. ...Read more

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Is it possible that a vegan diet could obscure kidney disease in lab tests? Is an eGFR of 79 in a diabetic with low blood protein kidney disease?

Is it possible that a vegan diet could obscure kidney disease in lab tests? Is an eGFR of 79 in a diabetic with low blood protein kidney disease?

Could be: A normal eGFR is higher than 90. Vegans have lower creatinine than meat eaters, and should have higher eGFR. Creatinine is the main factor in determining eGFR. It would be prudent to consult a nephrologist to rule out treatable issues and to have a close follow-up. ...Read more

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Can a man with stage 3 kidney disease take 20mg of cialis?

Can a man with stage 3 kidney disease take 20mg of cialis?

With caution.: Caution is recommend with Cialis use in patients with decreased kidney function. Dosing of Cialis needs to be adjusted in kidney disease, and is based on gfr. Stage 3 represents a GFR of 30-59ml/min. The dose is 5mg once per day max. For kidney function worse than this, 5mg once every 72 hours is possible, but not recommended. ...Read more

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How muchdiseases day should I drink with stage 3 kidney disease?

Under 2 liters: Under 65-70 ounces total. Not over 70 ounces. Note if you have swelling, you are drinking too much. ...Read more

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Is a 20mg Cialis pill safe for a man with stage 3 kidney disease?

Is a 20mg Cialis pill safe for a man with stage 3 kidney disease?

Cialis in Stage 3: Yes, it is. See your nephrologist and he will tell you that the only absolute contraindication against taking drugs like Cialis is using nitrates. This is because nitrates lower blood pressure by vasodiliation. Kidney function, at any level, is not a problem taking drugs like cialis. ...Read more

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What effect does Cialis have on person with stage 3 kidney disease?

What effect does Cialis have on person with stage 3 kidney disease?

Cialis in Stage 3: Patients with all stages of chronic kidney disease can take Cialis with no problems. Cialis cannot be used in men taking nitrates for cardiac disease. If you are not on these medicines, go ahead and take Cialis as often as you need to. ...Read more

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Please tell me how long it takes for to fall from stage 3 kidney disease to dialysis?

No single answer: It can range from "never", to "few months" in the worst case scenario. There are red flags that are predictive of a worst outcome like uncontrolled blood pressure or massive amounts of protein in the urine. There are some equations that can help nephrologists make a reasonable prediction, but they are not quite as good as crystal balls! ...Read more

Previous Kidney Disease (Definition)

Polycystic kidney disease is a kidney disorder passed down through families in which multiple cysts form on the kidneys, causing ...Read more


Dr. Tarek Naguib
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