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Doctor insights on: Does Spironolactone Lower Testosterone In Men

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Dr. Anita Deswal
422 Doctors shared insights

Spironolactone (Definition)

Treats fluid retention (edema) in patients with congestive heart failure, liver cirrhosis, or nephrotic syndrome. Also treats high blood pressure, heart failure, and low blood potassium (hypokalemia). This medicine is ...Read more


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Does spironolactone for men block testosterone & causes impotence?

Does spironolactone for men block testosterone & causes impotence?

Common side effect: Spironolactone is considered a testosterone-blocker. While it is a blood pressure medication, it has side effects of breast development, decreased erections - particularly morning erections. Many transgender people use spironolactone as they are transitioning from male to female. LGromkoMD ...Read more

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Can spironolactone lower your androgens to low? Dhyi and andro labs below normal, testosterone normal. Is this desired or can it cause problems?

Can spironolactone lower your androgens to low? Dhyi and andro labs below normal, testosterone normal. Is this desired or can it cause problems?

No: Spironolactone blocks androgen effect by blocking Androgen receptors but it does not lower Androgen level. It is commonly used to relief symptoms of Androgen excess like hirsutism (excessive body & facial hair). Be careful it is teratogenic (may cause birth defects) and should be used with a reliable method of contraception. ...Read more

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High bioavailable testosterone. Will spironolactone lower it? How about finasteride? Total Testosterone normal. Can flutamide help and at what dose?

High bioavailable testosterone. Will spironolactone lower it? How about finasteride? Total Testosterone normal. Can flutamide help and at what dose?

Here's some...: Have you been compulsively to perfect your body? Reviewing your profile incites me to raise this question. With so much involvement in your care, you should collect, reserve, & bring all related questions to your treating Dr. For balancing between medical necessity and professional possibilities before further acting upon with medication. Online inquiry will not suffice to address your Q. ...Read more

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Does spironolactone block testosterone?

Does spironolactone block testosterone?

Not really: Spironolactone is an old, commonly used (but not really effective) diuretic that has an interesting side effect: its chemical structure is similar enough to block testosterone receptors in the face and scalp, and helps to decrease acne, oily skin, and facial hair growth. ...Read more

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How spironolactone decreases testosterone production in a pcos woman?

How spironolactone decreases testosterone production in a pcos woman?

It doesn't: Spironolactone is a diuretic that also happens to block testosterone receptors in hair follicles. Since many women with P COS experience some degree of hirsutism as a result of the elevated testosterone common with PCOS the Spironolactone is prescribed to block the receptors to prevent those hair changes. The testosterone production can be decreased by suppressing the ovaries with OCP's. ...Read more

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Since spironolactone is a testosterone blocker, would that be bad for the body or decreases testosterone level.

Since spironolactone is a testosterone blocker, would that be bad for the body or decreases testosterone level.

Does not lower level: Spironolactone is not a "testosterone" blocker per say. It designed to block aldosterone receptors from being activated. It is not perfect and does have some anti-masculine side effects (gynecomastia). If a doctor prescribed your medication for blood pressure control, prior heart attack, heart failure, or liver disease it is more likely to make you live longer and better than not. ...Read more

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Taking 100 mg Spironolactone daily and testosterone is still too high. Are there additional methods for lowering androgens in women?

Taking 100 mg Spironolactone daily and testosterone is still too high. Are there additional methods for lowering androgens in women?

Weight loss: The best way to improve metabolic issues to achieve and maintain ideal body weight. Until weight is managed, no treatment will work well. ...Read more

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Does spironolactone actually increase basal levels of estrogen or does it just block androgens, decreasing testosterone?

Does spironolactone actually increase basal levels of estrogen or does it just block androgens, decreasing testosterone?

Spironolactone: 26F NY asks: Does spironolactone actually increase basal levels of estrogen or does it just block androgens, decreasing testosterone? ANS: complex: decrease T production by testis, increases T conversion to E2 so more estrogen and displaces T from SHBG. Binds with T receptors thus acting like anti T. I specialize in BP and diet and drug RX. Happy to do 2nd opinion. ...Read more

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Can spironolactone help reduce androgenetic alopecia even if my testosterone is normal? If so, what dose do you recommend?

Can spironolactone help reduce androgenetic alopecia even if my testosterone is normal? If so, what dose do you recommend?

Maybe: If your alopecia is truly androgenic, then, by definition, it is driven by androgen (dht). Spironolactone will provide blockade which may help. Your md should give the dose. ...Read more

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I'm a 20 yr old female recently put on spironolactone for acne most likely because of high testosterone. What should I expect?

I'm a 20 yr old female recently put on spironolactone for acne most likely because of high testosterone. What should I expect?

A good result: Don't try to figure out the cause of one's acne. High or normal for a woman, spironolactone suppresses androgens that promote acne. This illness is a serious personal and professional liability. Your physician should be commended for thinking of this medicine, which is often overlooked as an option. ...Read more

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Anything else besides Spironolactone, Finasteride, Metformin & bcps that help acne & block testosterone from PCOS? Do work but can't tolerate them.

Anything else besides Spironolactone, Finasteride, Metformin & bcps that help acne & block testosterone from PCOS? Do work but can't tolerate them.

Many meds: In my opinion there are too many meds on the list.
Please discus this with your primary doctor.
If she/he continues with the number of meds you mention, please see someone with a bit mores sense.

Not surprised you can't tolerate medical items.
Please keep me informed. ...Read more

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Transgender-man2fem-is there a bloodworkless way to tell weakness/fatigue caused by electrolyte imbalance (aldactone) vs muscle loss/low testosterone?

Transgender-man2fem-is there a bloodworkless way to tell weakness/fatigue caused by electrolyte imbalance (aldactone) vs muscle loss/low testosterone?

No: For what you've listed, you need labs eg blood needs to be drawn. However, do know that there are other reasons for weakness & fatigue such as medications, supplements (see http://www. Usatoday. Com/story/news/nation/2014/05/09/tests-find-synthetic-stimulants-iforce-nutrition-dexaprine-xr/8905197/ for example of adulterated stuff), thyroid, depression, etc. Best to discuss your concerns w/your doc. ...Read more

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Can stress or anxiety lower testosterone in men?

Can stress or anxiety lower testosterone in men?

Defitely yes: Testosterone levels can decrease with acute or chronic stress or anxiety. Theory is that the stress or "flight and fright" hormoes, epinephrine, nor-epinephrine and cortisol. This lowers the anabolic (tissue build up) process and inhibits testosterone production. This is reversed after stress and anxiety are relieved. ...Read more

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Could soy raise estrogen and lower testosterone in men?

Could soy raise estrogen and lower testosterone in men?

Partly: Common question and concern. I do not know of any reliable research showing soy increases estrogen levels in men. There are case reports of soy isoflavones lowering free testosterone though. Personally, I avoid soy (including lecithin) as much as possible. ...Read more

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Can taking Abilify (aripiprazole) lower testosterone in men?

Can taking Abilify (aripiprazole) lower testosterone in men?

Yes but. . .: Abilify (aripiprazole), like all antipsychotics, has some effect on the pituitary but possibly less than Risperdal (risperidone), which can decrease testosterone production by increasing prolactin. See answer to this question: https://www. Healthtap. Com/#user_questions/248515-do-respiridone-and-abilify-reduce-testosterone-or-increase-estrogen. Tell your doc about your concerns & ask for options. ...Read more

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Bf born without thyroid. Does it effect men sexually? Lower testosterone

Shouldn't. . .: Thyroid controls metabolism but not sexual development or maturation. Pituitary controls both thyroid & testes but if he's only missing thyroid, then testes should be ok. However, if testosterone is low, need to figure out why. Low t might be due to testicular issue (coincident w/thyroid) or be due to pituitary problem (see above) or perhaps liver (via excess iron - hemochromatosis), etc. Go c doc. ...Read more

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Does it happen that thyroxine replacement therapy lower estradiol in Men? Or does the replacement affect the level of testosterone aromatization?

Does it happen that thyroxine replacement therapy lower estradiol in Men? Or does the replacement affect the level of testosterone aromatization?

Replacement: To my knowledge thyroxine does not lower estradiol, nor does if affect testosterone aromatization. Is your thyroxine replacement helping you? What are the problems you are having with testosterone? Please give me some more information and I will try and resolve some concerns. ...Read more

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How can using drugs decrease testosterone? Will a man be able to have kids if he was using drugs for over 15 yrs?

How can using drugs decrease testosterone? Will a man be able to have kids if he was using drugs for over 15 yrs?

Drugs: It depends entirely on the drugs he has been taking and how often.
Have him see his doctor who can then evaluate his testosterone status.
It could be fine. ...Read more

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Do men need to take testosterone?

Sometimes: Testosterone decreases1.5-1.8% every year after age 40. It's not just about sex and sex drive!
testosterone is important in many areas including bone health, energy level, Insulin resistance and depression among many other areas. There have been studies linking low testosterone with increased risk of all cause mortality. ...Read more

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Can men safely take testosterone in their 70s?

Yes!!!!!!!!!!!!!!!!!: As long as appropriate screening for latent prostate cancer is performed, then older men can safely take it if they need it. Interestingly there are studies that suggest safety in localized cancer. ...Read more

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What happens if men are testosterone driven, what about women?

What happens if men are testosterone driven, what about women?

Confusing question: I'm not sure what you are asking. Men are different than women because they have high testosterone levels which affect muscle strength and development as well as some brain changes. Women have naturally low testosterone but high estrogen levels. "Drive" or motivation is not necessarily related to hormone levels. Don't let anyone give you testosterone to increase your "drive" ...Read more

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Are western men lacking in testosterone moreso than eastern men?

Are western men lacking in testosterone moreso than eastern men?

Both places: Hi. Some men are lacking in testosterone in BOTH places...they're the ones with all the guns and who subjugate women. ...Read more

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What are typical testosterone levels in old men?

Lower than young men: I know, not the answer you wanted, but it's true. When looking at large groups of men, older men tend to have lower t levels than younger men. But there are also some older men w/higher t than some younger men & vice versa. Normal reference ranges also depend upon lab, equipment used & test ordered. Individual results vary w/time of day. More important than typical t level is how you feel. ...Read more

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Does masturbating a lot effect testosterone levels in men?

Does masturbating a lot effect testosterone levels in men?

No: There is no known relationship between frequency of ejaculation and production of testosterone ...Read more

Men (Definition)

Men are adult members of the male sex. The acropnym men also stands for multiple endocrine neoplasia, a hereditary condition that involves benign and malignant tumors of various glands. There are two main types, men ...Read more


Dr. Steven Griggs
239 Doctors shared insights

Aldactone (Definition)

Aldactone is a potassium-sparing agent which is a kind of water pill or diuretic (heart ...Read more